BPS2024 Full Program & Abstracts

Membership Committee Meeting 3:30 pm - 5:30 pm, Room 106AB Career Development Center Workshop Negotiation for Biophysicists: Negotiation Strategies and Tactics and Evaluating a Job Offer 4:00 pm - 5:00 pm, Room 108B We will address strategies and tactics to evaluate a job offer and to negotiate for what you are worth in the employment marketplace, including postdoc and faculty roles. Symposium Gating Modalities of Mechanically-Activated Ion Channels 4:00 pm - 6:00 pm, Ballroom A Chair Swetha Murthy, Oregon Health and Science University, USA 980 -Symp 4:00 pm MOLECULAR CHOREOGRAPHY OF PIEZO1 IN DEVELOPMENT AND REPAIR. Medha Pathak 981-Symp 4:25 pm EVOLUTIONARY APPROACHES TO CELLULAR AND MOLECULAR MECHA NOTRANSDUCTION. Eduardo Perozo 982 -Symp 4:50 pm CENTRAL PORE-OPENING STRUCTURE AND GATING OF THE MECHANO SENSITIVE PIEZO1 CHANNEL. Bailong Xiao 983 -SympSelect 5:15 pm DYNAMICAL MECHANISM OF ELECTROMECHANICALLY DISCORDANT ALTERNANS DUE TO MECHANO-CHEMO-ELECTRO-TRANSDUCTION FEEDBACK. Asuka Hatano , Leighton T. Izu, Ye Chen-Izu, Daisuke Sato 984 -Symp 5:35 pm THE ROLE OF LIPIDS IN GATING OSCA/TMEM63A FAMILY. Swetha Murthy Symposium Climate Change: Adaptation to Temperature Changes 4:00 pm - 6:00 pm, Ballroom B Chair Kavita Rangan, University of California, San Diego, USA No Abstract 4:00 pm BIOPHYSICS IN THE CHEMISTRY OF CO2 CONVERSION AND CAPTURE. Peter Agbo 985-Symp 4:30 pm RECONSTITUTION OF THE BACTERIAL CO 2 CONCENTRATING MECHA NISM. David F. Savage 986-Symp 5:00 pm DEVELOPMENT OF INTRINSICALLY DISORDERED REGIONS-BASED BIO SENSORS FOR STUDYING SENSING AND ACCLIMATION TO STRESS. Cesar L. Cuevas-Velazquez , Constanza Enriquez-Toledo, Cesar A. Ponce-Diego, Gala R. Lopez-Herrera, Esau E. Rodriguez, Samantha Barron-Huerta

• We will describe how FLIM is streamlined. It’s rapidFLIM hardware can record several frame per second with high photon count rates, which the software handles with a novel dynamic binning format. In combination with GPU-accelerated algorithms, this enables high-speed automated analysis of FLIM images with minimal user interactions. As an outlook we will demonstrate how Luminosa can combine FLIM with super-resolution imaging modalities. Speakers Marcelle Koenig, Senior Scientist R&D, PicoQuant GmbH Evangelos Sisamakis, Product Manager Microscopy, PicoQuant GmbH Self-Advocacy for Career Success 2:30 pm - 4:00 pm, Room 111AB Achieve success and minimize obstacles by being an advocate for your self and others. At this workshop we will discuss identifying productive workplace conditions and career expectations, and recognizing and addressing challenges effectively. JUST-B (Justice for Underrepresented Scholars Train ing in Biophysics) Poster Session 3:00 pm - 5:00 pm, Grand Hall The JUST-B (Justice for Underrepresented Scholars Training in Biophys ics) Poster Session will celebrate the achievements of underrepresented and underserved students, postdocs, and early career researchers in the field of biophysics. The poster session will promote the endeavors of trainees, offer support through networking opportunities, and serve as a recruitment venue for those seeking to diversify their pool of future graduate students, postdocs, faculty, staff scientists, journal editors, or any other career within biophysics. All are welcome to attend. Exhibitor Presentation LUMICKS 3:30 pm - 5:00 pm, Room 103C Accelerating Biological Discovery: An Automated, End-to-End Solution in Single-Molecule Research Dynamic single-molecule research has revolutionized our understanding of biology by providing crucial insights into key molecular and cellular mechanisms, such as DNA repair and phase separation processes, among others. However, this field of science has traditionally been accessible only to experts capable of building and operating complex home-built instru ments, able to produce specific DNA or protein samples, and developing sophisticated algorithms for correct single-molecule data analysis and interpretation. To democratize access to single-molecule technolo gies, LUMICKS C-Trap was introduced as the first instrument of its kind. LUMICKS C-Trap uniquely combines optical tweezers, single-molecule fluorescence, and automated microfluidics, allowing the correlation of single-molecule force and fluorescence measurements in real time to enable the investigation of dynamic molecular mechanisms with a ready-to-go instrument. Here, we will unveil our latest advancements in creating a comprehen sive end-to-end solution designed to transform the field of dynamic single-molecule research: from a vast range of DNA and protein samples to the full automation for instrument set-up and experiment execution, all the way to a seamless data analysis and interpretation. Speaker Trey Simpson, Senior Application Scientist, LUMICKS

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