BPS2024 Full Program & Abstracts

1075-Pos Board B28 BIOPHYSICAL STUDIES OF THE PROMISCUOUS TRANSCRIPTION FACTOR ENGRAILED: PROPOSED MECHANISM FOR THE CONFORMATIONAL RESPONSE BY ELECTROSTATICS AND DNA RECOGNITION. Benjamin Tanielian , Mourad Sadqi, Victor Munoz 1076-Pos Board B29 THERMODYNAMICS OF FLUORIDE BINDING VERSUS THE OXIDATION REDUCTION OF HEME-FLUORIDE COMPLEXES OF HEMOGLOBIN AND MYOGLOBIN: REDOX IMPLICATIONS OF OXYGEN BINDING. Jose F. Cerda , Kayla G. Flanders, Annie Mathew 1077-Pos Board B30 CHARACTERIZATION OF HETEROMERIC STATE OF NOVEL FUNCTIONAL CATECHOL 1,2-DIOXYGENASE USING SMALL-ANGLE X-RAY SCATTER ING. Shirish N.C. Chodankar , Arisbeth Guadalupe Almeida-Juarez 1078-Pos Board B31 EXTRACELLULAR ADHERENCE PROTEINS, MEMBERS OF A STAPHYLO COCCAL IMMUNE EVASIONPROTEIN FAMILY, ENGAGE MULTIPLE NEU TROPHIL SERINE PROTEASES SIMULTANEOUSLY. Carson D. Gido 1079-Pos Board B32 DISSECTION OF HIV-1 IMMATURE PARTICLE ASSEMBLY. Siddhartha A. Datta , Peter Schuck, Alan Rein Protein Structure, Prediction, and Design II (Boards B33 - B47) 1080-Pos Board B33 CONSTRUCTING A DE NOVO CHARGE SEPARATING TRIAD. Paul M. Mo linaro , Marlene McKinney, Ronald Koder 1081-Pos Board B34 ENHANCED SAMPLING SIMULATIONS OF BIOMOLECULAR SYSTEMS. Edi na Rosta 1082-Pos Board B35 UNDERSTANDING HIV BNAB INTERACTIONS THROUGH STRUCTURE PRE DICTION AND MD SIMULATIONS. Shahlo Solieva , Rumi Habib, Gregory R. Bowman, Daniel Kulp 1083-Pos Board B36 UNRAVELING BET PROTEINS: A MULTI-MODAL APPROACH TO NOVEL BINDERS DISCOVERY AND INHIBITORS DESIGN. Arup Mondal , Monica J. Roth, Gaetano T. Montelione, Alberto Perez 1084-Pos Board B37 ENHANCING PHOTOSYNTHESIS IN CYANOBACTERIA: MOLECULAR DOCK ING OF PROCAINE HYDROCHLORIDE WITH ATP SYNTHASE PROTEIN. Mst Sayadujjhara 1085-Pos Board B38 DE NOVO DESIGN OF ROBUST AND MUTATION-TOLERANT “RECEPTOR BODIES” TO NEUTRALIZE ACE2-DEPENDENT SARBECOVIRUSES. Santanu Sasidharan , Shawn C.C. Hsueh, Pranav Garg, Nobuhiko Tokuriki, Steven Board B39 WAVELENGTH-DEPENDENT FLUORESCENCE FLUCTUATION ANALYSIS OF AN MCERULEAN3-LINKER-MCITRINE CONSTRUCT FOR ENVIRONMEN TAL IONIC STRENGTH SENSING AT THE SINGLE-MOLECULE LEVEL. Clint McCue , Sarah Mersch, Taryn M. Kay, Arnold J. Boersma, Erin D. Sheets, Ahmed A. Heikal 1087-Pos Board B40 COMPUTING A BAYESIAN MULTI-STATE MODEL OF A PROTEIN STRUC TURE FROM AN X-RAY DIFFRACTION PATTERN. Matthew P. Hancock , James S. Fraser, Andrej Sali S. Plotkin 1086-Pos

1088-Pos Board B41 FINDING THE FREQUENCY OF OCCURRENCE OF AMINO ACIDS IN DIF FERENT TYPES OF PROTEIN Β-STRUCTURES. Natalia Osorio , Paulo F. Almeida, Jaime Cardenas, Alex Elms 1089-Pos Board B42 COMBINING ALPHAFOLD AND MOLECULAR DYNAMICS SIMULATIONS TO DETERMINE THE COMPLETE STRUCTURES OF ISOFORMS OF HU MAN BRAIN-DERIVED NEUROTROPHIC FACTOR AND HUMAN NERVE GROWTH FACTOR. Sukhvershjit Aulakh , Margaret Fahnestock, Maikel C. Rheinstadter 1090-Pos Board B43 IN SILICO MECHANICS OF MINI-PCDH15 PROTEINS RATIONALLY DESIGNED FOR INNER-EAR GENE THERAPY. Haosheng Wen , Pedro De la-Torre, Karina Martínez-Pérez, Joseph Brower, Yoshie Narui, Maryna Ivanchenko, David P. Corey, Marcos M. Sotomayor, Artur A. Indzhykulian 1091-Pos Board B44 DESIGNING PROTEINS TO FOLD WITHOUT COTRANSLATIONAL CHAPER ONE ASSISTANCE. Kibum Park , Eugene Shakhnovich 1092-Pos Board B45 EVOLUTIONARY INSIGHTS AND STRUCTURAL ANALYSIS OF ENZYME THERMAL ADAPTATION: A DEEP LEARNING APPROACH. Divyanshu Shukla 1093-Pos Board B46 COMPARATIVE ANALYSIS OF PSYCHROPHILIC SERINE PROTEASES. Eliza beth M. Diessner, Gemma R. Takahashi, Carter T. Butts, Rachel W. Martin 1094-Pos Board B47 PREDICTING RELATIVE POPULATIONS OF PROTEIN CONFORMATIONS WITHOUT A PHYSICS ENGINE USING ALPHAFOLD2. Gabriel M. da Silva , Jennifer Y. Cui, David C. Dalgarno, George P. Lisi, Brenda M. Rubenstein Protein Stability, Folding, and Chaperones II (Boards B48 - B65) 1095-Pos Board B48 EFFECTS OF CONFINEMENT AND INTERFACIAL INTERACTIONS ON FLA VADOXIN STABILITY. Nakoa K. Webber , Lauren Savage, Ayaz Mahmood, Lauren Staman, Nathaniel V. Nucci 1096-Pos Board B49 INVESTIGATION OF THE STABILITY OF MYOGLOBIN IN THE PRESENCE OF AMINO ACID IONIC LIQUIDS. Kristen N. Rass , Dimitra Kossis, Eustratios Kossis, Taha Shahbaz, CHUN WU, Timothy Vaden, Gregory A. Caputo 1097-Pos Board B50 ELUCIDATING THE CONFORMATIONAL DYNAMICS OF HUMAN HSP90 USING SMFRET. Ecenaz Bilgen , Stefan Riedl, Ganesh N. Agam, Johannes Buchner, Don C. Lamb 1098-Pos Board B51 STUDIES OF BASIC AND ACIDIC FIBROBLAST GROWTH FACTOR INTERAC TIONS WITH CARBOHYDRATES. Robert J. Allsopp, Jeffery B. Klauda 1099-Pos Board B52 EXAMINATION OF AGING-RELATED LOSS OF PROTEOSTASIS IN YEAST WITH LIMITED PROTEOLYSIS MASS SPECTROMETRY. Neil B. Wood , Haley E. Tarbox, Stephen D. Fried 1100-Pos Board B53 IDENTIFYING AND VALIDATING ENHANCED VARIANTS IN NBD2 OF HSP104. Alondra N. Betancourt , Zarin Tabassum, James Shorter

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