BPS2024 Full Program & Abstracts

Protein-Nucleic Acid Interactions I (Boards B188 - B219)

1248-Pos Travel Award Winner MOLECULAR GRAMMAR UNDERLYING THE DNA BINDING PROTEIN CREN7 IN CRENARCHAEOTA. Soumit Sankar Mandal 1249-Pos Board B202 E. COLI RECBCD NUCLEASE DOMAIN REGULATES HELICASE ACTIVITY BUT NOT SINGLE STRANDED DNA TRANSLOCATION ACTIVITY. Kacey N. Mersch , Nicole T. Fazio, Linxuan Hao, Timothy M. Lohman 1250-Pos Board B203 DNA FOLDING BY SARS-COV-2 NUCLEOCAPSID PROTEIN. Jonathan Xing , Youna J. Choi, Ashley Carter 1251-Pos Board B204 INTERACTIONS OF SARS COV-2 NSP7 OR NSP8 WITH NSP12 CAUSES SEVERE CONSTRICTION OF RNA ENTRY CHANNEL: IMPLICATIONS FOR NOVEL RDRP INHIBITOR DRUG DISCOVERY. Deepa Singh, Tushar Kushwaha, Rajkumar Kulandaisamy, Vikas Kumar, Kamal Baswal, Saras H. Tiwari, Arkadyuti Ghorai, Mohan B. Appaiahgari, Krishna K. Inampudi 1252-Pos Board B205 BASIC RESIDUES OF HIV-1 NUCLEOCAPSID PROTEIN MODULATE DNA CONDENSATION FUNCTION AND VIRAL REPLICATION. Helena Gien , Michael Morse, Micah J. McCauley, Robert Gorelick, Ioulia F. Rouzina, Mark C. Williams 1253-Pos Board B206 DOWN THE CHAIN OF PROTEIN-DNA BINDING INTERACTIONS. Taylor Board B207 A DNA UNWINDING EQUILIBRIUM SERVES AS A CHECKPOINT FOR CRISPR-CAS12A TARGET DISCRIMINATION. Jaideep Singh, Kevin Liu, Aleique Allen, Wei Jiang, Peter Z. Qin 1255-Pos Board B208 DISENTANGLING THE EFFECTS OF THE N-TERMINAL TAILS OF HISTONE H3 AND CENP-A FROM THE HISTONE CORE ON NUCLEOSOME STABIL ITY. Joshua J. Lee , Jeffery M. Wereszczynski 1256-Pos Board B209 HYDROPATHY OF DNA-PROTEIN INTERFACE IN NUCLEOSOMES. Rat nakshi Mandal 1257-Pos Board B210 MECHANISM OF MISMATCH RECOGNITION BY MUTS IN LINEAR AND CIRCULAR DNA. Saroj Baral , Viktoriya Zvoda, Ying Z. Pigli, Phoebe A. Rice, Edwin Antony, Anjum Ansari 1258-Pos Board B211 MICRORNAS CONTROL THE TRANSCRIPTIONAL PROFILING IN MUMPS VIRUS INFECTION: A COMPUTATIONAL ANALYSIS. Saba Shahzadi , Mubasher Hassan, Zainab Yaseen, Muhammad Iqbal, Andrzej Klocz kowski 1259-Pos Board B212 Travel Award Winner ELUCIDATION OF SACCHAROMYCES CEREVISIAE MSH2-MSH6 AND HOL LIDAY JUNCTION BINDING INTERACTIONS VIA UV PHOTOCROSSLINK ING. Tai Lon Tan , Zane Lombardo, Ishita Mukerji 1260-Pos Board B213 PROTECTION OF DNA FROM MECHANICAL STRESSES AT THE NUCLEAR ENVELOPE. Ramesh Adakkattil 1261-Pos Board B214 STRUCTURE AND DNA BRIDGING ACTIVITY OF THE ESSENTIAL REC114 MEI4 TRIMER INTERFACE. Kaixian Liu , Emily M. Grasso, Stephen Pu, Mengyang Zou, Shixin Liu, David Eliezer, Scott Keeney Board B201 Kranbuhl 1254-Pos

M O N D A Y

1235-Pos Board B188 VISUALISING THE SELF-ASSEMBLY DYNAMICS OF ICOSAHEDRAL VIRUSES THROUGH FLUORESCENCE MICROSCOPY AT THE SINGLE PARTICLE LEVEL. Thomas Bugea , Laetitia Gargowitsch, Charles Truong, Karen Per ronet, Guillaume Tresset 1236-Pos Board B189 MEASURING SITE SPECIFIC DNA CLEAVAGE AT THE SINGLE MOLECULE LEVEL. Krysten Rafferty, Katie Polanco, Harold Sartiah, Allen C. Price 1237-Pos Board B190 RECOGNITION OF RECOMBINATION INTERMEDIATES BY THE MISMATCH REPAIR PROTEIN MSH2-MSH6. Zane Lombardo , Tai Lon Tan, Ishita Mukerji 1238-Pos Board B191 SINGLE MOLECULE FRET INVESTIGATION OF BINDING AND THE COM PARATIVE EFFECT OF DNA ARCHITECTURAL PROTEINS ON HOLLIDAY JUNCTION CONFORMATIONAL DYNAMICS. Farhana Islam 1239-Pos Board B192 OPTICAL TWEEZERS REVEAL NANOMOLAR DNA BINDING AFFINITY OF DOXORUBICIN. Jason Martin , Zachary Ells, Brian Dolle, Ioulia F. Rouzina, Mark C. Williams, Thayaparan Paramanathan 1240-Pos Board B193 EXPLORING THE INTERACTION OF NETROPSIN AND DNA THROUGH CONSTANT FORCE EXPERIMENTS AND SLOW STRETCHING EXPERI MENTS USING OPTICAL TWEEZERS. Jacob McNally , Youri K. Nabhan, Irbazhusain Shaikh, Thayaparan Paramanathan 1241-Pos Board B194 EXPLORING THE BINDING KINETICS OF CHEMOTHERAPEUTIC MITOXAN TRONE TO DNA USING OPTICAL TWEEZERS. Aaron J. Ferreira , Helena K. Beeloo, Thayaparan Paramanathan 1242-Pos Board B195 EXPRESSION OF SOLUBLE METHANE MONOOXYGENASE WITH EN HANCER BINDING PROTEIN AND SIGMA54 THROUGH INTERACTIONS TO PROMOTERS. Yunha Hwang , Seung Jae Lee 1243-Pos Board B196 DIFFERENTIAL DYNAMICS SPECIFY MECP2 FUNCTION AT NUCLEOSOMES AND METHYLATED DNA. Gabriella N.L. Chua , Shixin Liu 1244-Pos Board B197 EXPLORING MIRNAS AS TRANSCRIPTIONAL PROFILERS IN RESPIRATORY SYNCYTIAL VIRUS INFECTION THROUGH BIOINFORMATICS STUD IES. Mubasher Hassan, Saba Shahzadi, Andrzej Kloczkowski 1245-Pos Board B198 UNCOATING OF HIV-1 CAPSID IS REGULATED BY LONG DOUBLE-STRAND ED DNA PRODUCTS OF REVERSE TRANSCRIPTION AND NUCLEOCAPSID PROTEIN-MEDIATED DNA CONDENSATION. Michael Morse , Ryan C. Burdick, Ioulia Rouzina, Vinay K. Pathak, Mark C. Williams 1246-Pos Board B199 Travel Award Winner WHY NUCLEOSOME BREATHING DYNAMICS IS ASYMMETRIC? Anupam Mondal , Anatoly B. Kolomeisky 1247-Pos Board B200 LEDGF AND HDGF2 DESTABILIZE NUCLEOSOMES AND FACILITATE REAS SEMBLY. Joha Joshi , Micah J. McCauley, Michael Morse, Zelin Shan, Tao Jing, Nicole A. Becker, Ioulia F. Rouzina, Louis J. Maher, Dmitry Lyumkis, Mark C. Williams

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