BPS2024 Full Program & Abstracts

1344-Pos Board B297 MECHANOTRANSDUCTION AT A DISTANCE:HOW CELLS CAN SENSE MA TRIX PROPERTIES USING CALCIUM. Benjamin M. Goykadosh , Vasuretha Chandar, Harikrishnan Parameswaran 1345-Pos Board B298 UNVEILING THE IMPACT OF FAK AND P130CAS ON EARLY TRANSCRIP TIONAL REGULATION OF CELLULAR METABOLISM IN RESPONSE TO ECM STIFFNESS. Bat-Ider Tumenbayar, John C. Biber, Vincent M. Tutino, Yongho Bae 1346-Pos Board B299 UNDERSTANDING THE ROLE OF K60 IN STABILIZING THE OPEN STATE OF E COLI MSCS. Phuong T. Nguyen, Hannah R. Malcolm 1347-Pos Board B300 Travel Award Winner PIEZO1-HALOTAG HISPC LINES: A NEW TOOL TO ASSAY PIEZO1 LOCAL IZATION AND ACTIVITY FROM SINGLE CELLS TO TISSUE ORGANOIDS. Ga briella A. Bertaccini , Elizabeth Evans, Jamison L. Nourse, George D. Dickinson, Gaoxiang Liu, Ignasi Casanellas, Sayan Seal, Alan Ly, Jesse Holt, Shijun Yan, Elliot Hui, Mitradas Panicker 10 , Srigokul Upadhyayula 11 , Ian Parker, Medha M. Pathak 12 1348-Pos Board B301 MECHANO-INDUCED ATRIAL CONDUCTION SLOWING IS MEDIATED BY ACTIVATION OF CAVEOLAR I CL,SWELL AND AUGMENTED DURING CHRONIC HYPERTENSION PROMOTING ATRIAL ARRHYTHMOGENESIS. Yuriy V. Egorov, Daniel G.P. Turner, Thomas A. Schrauth, Jake T. Bamlett, Roman Y. Medvedev, Alexey V. Glukhov 1349-Pos Board B302 THE CONTRIBUTION OF PIEZO1 CHANNELS MODIFIES OUR PICTURE OF SKELETAL MUSCLE CONTRACTION. Beatrix Dienes , Peter Szentesi, Laszlo Szabo, Zsuzsanna Édua Magyar, Zsigmond Kovacs, Tamás Bazsó, Mónika Gönczi, László Csernoch 1350-Pos Board B303 SARCOLEMMAL PROTEIN REORGANIZATION MAY UNDERLIE ARRHYTH MIA SUSCEPTIBILITY IN SARCOSPAN-DEFICIENT MICE. Aida Rahimi Kahmini , Michelle S. Parvatiyar, Christopher Solís 1351-Pos Board B304 ELUCIDATING THE SOURCE OF COLLAGEN PERSISTENCE LENGTH FROM ALL-ATOM MOLECULAR DYNAMICS SIMULATION. George A. Pantelopu los , Robert B. Best 1352-Pos Board B305 PIEZO1-TMEM16F COUPLING IN RED BLOOD DISORDERS. Huanghe Yang , Pengfei Liang, Yang Zhang, Yui Chun S. Wan, Shang Ma, Ping Dong, Augustus Lowry, Samuel J. Francis, Sanjay Khandelwal, Martha Dela hunty, Marilyn J. Telen, John J. Strouse, Gowthami Arepally 1353-Pos Board B306 LINOLEIC ACID IMPROVES PIEZO2 DYSFUNCTION IN A MOUSE MODEL OF ANGELMAN SYNDROME. Luis O. Romero , Rebeca C. Caires Mugarra, A. Kaitlyn Victor, Juanma Ramirez, Francisco J. Sierra Valdez, Patrick Walsh, Vincent Truong, Jungsoo Lee, Ugo Mayor, Lawrence T. Reiter, Julio F. Cordero-Morales, Valeria Vásquez 1354-Pos Board B307 CORRELATING SINGLE MOLECULE INTERACTIONS WITH T CELL PERFOR MANCE. Hannah M. Stephens , Aoi Akitsu, Robert J. Mallis, Wonmuk Hwang, Ellis L. Reinherz, Matthew J. Lang 1355-Pos Board B308 MECHANOSENSITIVE TRPV4 RELOCATION TO THE PLASMA MEMBRANE BY CELL CROWDING ACTIVATES A CONTRACTILITY PROGRAM TO EN HANCE INVASION. Xiangning Bu, Teresa Vitali, Sulgi Lee, Kangsun Yun, Sana Tabbara, Patricia Latham, Christine Teal, Inhee Chung

1356-Pos Board B309 ASYMMETRIC INTERFACIAL ANCHORS REVEAL PRINCIPLES OF GATING AND METABOLIC CONTROL OF THE BACTERIAL MECHANOSENSITIVE CHANNEL MSCS. Madolyn Britt, Elissa Moller, Joseph Maramba, Andriy Anishkin, Sergei Sukharev 1357-Pos Board B310 PAN-TISSUE SCALING OF STIFFNESS VERSUS FIBRILLAR COLLAGEN REFLECTS CONTRACTILE-STRAIN DRIVEN COLLAGEN DEGRADA TION. Karanvir Saini , Sangkyun Cho, Manu Tewari, Abdelaziz Jalil, Mai Wang, Alex Kasznel, Kazuhiro Yamamoto, David M. Chenoweth, Dennis Board B311 ELECTRO-OSMOTIC FLOW PROMOTES CELL POLARITY AND TISSUE REPAIR. Md Moin Uddin Talukder, Mark Messerli 1359-Pos Board B312 Travel Award Winner SPATIAL DISTRIBUTION OF ADHESION FORCE GENERATION IN HUMAN CARDIOMYOCYTES. Abigail Nagle , Cherry Leung, Michael Regnier, Jen nifer M. Davis 1360-Pos Board B313 SPATIALLY RESOLVING MEMBRANE TENSION VIA FLUORESCENCE SINGLE CHANNEL FLUX RECORDING IN PIEZO1 CHANNELS. Muye He, Yue Xing, Michael Zucker, Philip A. Gottlieb, Arnd Pralle Excitation-Contraction Coupling (Boards B314 - B325) 1361-Pos Board B314 FUNCTIONAL ANALYSIS OF CA 2+ SIGNALING IN A MOUSE MODEL OF MALIGNANT HYPERTHERMIA. Toshiko Yamazawa , Takashi Murayama, Nagomi Kurebayashi, Kotaro Oyama, Madoka Suzuki 1362-Pos Board B315 CALCIUM-CALMODULIN DEPENDENT PROTEIN KINASE II REGULATION BY METHYLATION. Brian B. Nguyen 1363-Pos Board B316 HYDROGEN SULFIDE INCREASES EXCITATION-CONTRACTION COUPLING EFFICIENCY AND MODULATES LCC AND SERCA2A FUNCTION IN HY PERTENSIVE RATS. Grecia J. Medina Terol , Luis F. Chimal Ávila, Maritza Mayorga Luna, Karla Carvajal, David Centurión, Norma L. Gómez Viquez 1364-Pos Board B317 SEX-DIFFERENCES IN TWO-HIT MURINE MODEL OF HEART FAILURE WITH PRESERVED EJECTION FRACTION. Juliana Mira Hernandez , Erin Y. Shen, Christopher Y. Ko, Emily R. Spencer, Daria J. Smoliarchuk, Julie Bossuyt, Donald M. Bers, Bence Hegyi 1365-Pos Board B318 INTERPLAY OF ELECTRICAL AND MECHANICAL PROPERTIES IN TRANSGENIC RABBIT MODELS OF LONG-QT AND SHORT-QT SYN DROME. Nicolò Alerni , Saranda Nimani, Julien Louradour, Miriam Barbieri, Lucilla Giammarino, Stefanie Perez Feliz, Lluis Matas, Manfred .Zehender, Michael Brunner, Katja Odening 1366-Pos Board B319 ALTERATIONS OF LOCAL CA 2+ SIGNALING BY HIGH PACING FREQUENCY AND SHEAR STRESS IN RIGHT AND LEFT ATRIAL MYOCYTES. Joon-Chul Kim, Tran Nyguet Trinh, Phuong Kim Luong, Sun-Hee Woo 1367-Pos Board B320 EFFECTS OF NANODYSFERLINS ON RECOVERY OF VOLTAGE-INDUCED SR CALCIUM RELEASE AFTER OSMOTIC SHOCK IN MUSCLE FIBERS FROM DYSFERLIN-NULL MICE. Valeriy I. Lukyanenko , Joaquin M. Muriel, Robert J. Bloch E. Discher 1358-Pos

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