BPS2024 Full Program & Abstracts

1518-Pos Board B471 OPTIMIZATION OF A MACHINE-LEARNING-BASED APPROACH TO QUAN TIFY AND CHARACTERIZE MICROTUBULE DYNAMIC INSTABILITY. Sayan deepa Raha 1519-Pos Board B472 SELF-ORGANIZATION OF MICROTUBULES WITH CROSSLINKERS AND MOTORS. Prashali Chauhan , Jennifer M. Schwarz, Jennifer L. Ross 1520-Pos Board B473 Travel Award Winner MICROTUBULE POLYMERIZATION IS CONTROLLED BY INTERFACE-ACT ING NUCLEOTIDE. Lauren A. McCormick , Joseph M. Cleary, William O. Hancock, Luke M. Rice 1521-Pos Board B474 MECHANISM OF MICROTUBULE ASSEMBLY BY CKAP2. Susanne Bechst edt , Tanya Lyalina, Lia Paim Myosins (Boards B475 - B491) 1522-Pos Board B475 COOPERATIVITY OF WEAK INTERACTION OF SKELETAL MYOSIN AND UNREGULATED F ACTIN. Aarushi Naskar , Alexis Johnson, Yuri Nesmelov 1523-Pos Board B476 CHARACTERIZING THE CONCENTRATION AND LOAD-DEPENDENCE OF PHOSPHATE REBINDING TO FAST SKELETAL MYOSIN. Christopher P. Marang , Brent Scott, Edward P. Debold 1524-Pos Board B477 MYH3 MUTATIONS ASSOCIATED WITH DISTAL ARTHROGRYPOSIS ALTER THE CONTRACTILITY AND MYOSIN ISOFORM SWITCHING OF HIPSC DERIVED SKELETAL MUSCLE. Christian Mandrycky , Saffie Mohran, Mat thew C. Childers, Shawn M. Luttrell, Elizabeth Choi, Kati Buckingham, Michael J. Bamshad, David L. Mack, Michael Regnier 1525-Pos Board B478 MECHANSIMS OF TENSION FORMATION MEDIATED BY NONMUSCLE MYOSIN 2 PARALOGS IN BIOMIMETIC ACTIN ARRAYS. Philip Bleicher , Neil Billington, Ryan G. Hart, Christian A. Combs, Shureed Qazi, Indra Chandrasekar, Jay R. Knutson, James R. Sellers 1526-Pos Board B479 MECHANORESPONSIVE ADAPTABILITY IN PANCREATIC CANCER CELLS AND TISSUE. Eleana Parajon , Douglas N. Robinson 1527-Pos Board B480 CENTRIN 2 PROMOTES CATION DEPENDENT ASSEMBLY OF MYO15A BIOMOLECULAR CONDENSATES. James B. Heidings , Zane Moreland, Elli Hartig, Basile Tarchini, Jonathan Bird 1528-Pos Board B481 PHASE SEPARATION OF MYOSIN-15 AND CENTRIN-2 CONTRIBUTES TO STEREOCILIA TIP DENSITY FORMATION. Zane G. Moreland , James B. Heidings, Elli Hartig, Juan Guan, Basile Tarchini, Jonathan Bird 1529-Pos Board B482 MYOSIN 16A IS A SLOW ATPASE MOTOR. Susheel Pangieni , Takeshi Board B483 QUANTIFICATION OF EQUILIBRIUM OF MYOSIN ATP HYDROLYSIS BY LUCIFERASE ASSAY. Alexis Johnson , Aarushi Naskar, Yuri Nesmelov 1531-Pos Board B484 HUMAN MYOSIN-7A HAS MULTIPLE DISTINCT REGULATORY MECHA NISMS THAT MAKES IT AN EXCELLENT CANDIDATE AS TENSION ADAPTA TION MOTOR. Alexandra Hollo , Neil Billington, Yasuharu Takagi, Andras M. Kengyel, James R. Sellers, Rong Liu Sakamoto 1530-Pos

1532-Pos Board B485 MYOSIN WITH HYPERTROPHIC CARDIOMYOPATHY MUTATION M493I DEMONSTRATES ALTERED CROSSBRIDGE KINETICS AND FORCE SENSI TIVITY DESPITE NORMAL WORKING STROKE. Robert C. Cail , Bipasha Barua, Donald A. Winkelmann, Yale E. Goldman, E. Michael Ostap 1533-Pos Board B486 HIGHLIGHTING THE EFFECT OF MAVACAMTEN ON THE CHEMICAL STEP OF THE HUMAN CARDIAC BETA MYOSIN USING RARE-EVENT METH OD. Ananya Chakraborti , Jil C. Tardiff, Steven D. Schwartz 1534-Pos Board B487 INVESTIGATION OF POWER STROKE OF HUMAN CARDIAC MYOSIN WITH METADYNAMICS. Bai Hei , Jil C. Tardiff, Steven D. Schwartz 1535-Pos Board B488 MACHINE LEARNING-ENHANCED REAL-TIME & HIGH-THROUGHPUT TRACKING FOR THE IN VITRO MOTILITY ASSAY. Sebastian Duno-Miran da , David M. Warshaw, Shane R. Nelson 1536-Pos Board B489 EXPLORING MOLECULAR INTERACTIONS IN THE DROSOPHILA FLIGHT MUSCLE THICK FILAMENT: INSIGHTS INTO FLIGHTIN-MYOSIN BIND ING. Jiawei Li , Fatemeh Abbasi Yeganeh, Hosna Rastegarpouyani, Ken neth A. Taylor 1537-Pos Board B490 MYOSIN-1C COMPETES WITH TROPOMYOSIN 3.1 FOR BINDING TO ACTIN FILAMENTS. Luther W. Pollard , Malgorzata Boczkowska, Roberto Dominguez, E. Michael Ostap 1538-Pos Board B491 WNK1 ACTIVITY MODULATES BIOPHYSICAL PROPERTIES OF GLOMERU LAR PODOCYTES THROUGH REGULATION OF NON-MUSCLE MYOSIN II ACTIVATION. Zhenan Liu, Fouzia Ahmed, Joonho Yoon, R. Tyler Miller, Audrey N. Chang Multicellular, Consortium, and Tissue Modeling (Boards B492 - B505) 1539-Pos Board B492 Travel Award Winner REVEALING KEY MECHANISMS OF ATRIAL FIBRILLATION-ASSOCIATED FIBROSIS THROUGH COMPUTATIONAL MODELING OF CARDIAC FIBRO BLAST. Najme Khorasani , Haibo Ni, Dobromir Dobrev, Eleonora Grandi 1540-Pos Board B493 META-ANALYSIS OF STATIC MAGNETIC FIELDS EFFECTS ON BLOOD AND BONE TISSUE: A COMPREHENSIVE REVIEW. Savanna E.M. Murdock , Atif B. Malik, Joe P. D’Entremont 1541-Pos Board B494 MULTI-CELL MODELING OF THE SKELETAL MUSCLE MICROENVIRON MENT TO EXPLORE AGE-RELATED CHANGES IN SATELLITE CELL DYNAM ICS. Stephanie Khuu , Andrew D. McCulloch 1542-Pos Board B495 DYNAMIC COLLAGEN MATRIX MODEL FOR TISSUE SIMULATIONS ON DISTRIBUTED MEMORY SYSTEMS. Paul Brinkmeier , Julian M. Herold, Eric Behle, Alexander H. Schug 1543-Pos Board B496 IN SILICO DESIGN OF A MICROBIAL CONSORTIUM FOR CARBON-NEU TRAL BUTANOL PRODUCTION. Siqi Liao , Ting Lu 1544-Pos Board B497 HOW MUSCLE SOLVED THE GIBBS PARADOX. Josh E. Baker

M O N D A Y

96