BPS2024 Full Program & Abstracts

1573-Pos Board B526 CHEMSPACEAL: AN EFFICIENT ACTIVE LEARNING METHODOLOGY AP PLIED TO PROTEIN-SPECIFIC MOLECULAR GENERATION. Gregory W. Kyro , Anton Morgunov, Rafael I. Brent, Victor S. Batista 1574-Pos Board B527 Travel Award Winner AN AUTOMATED CHAIN TRACING ALGORITHM TO DETERMINE PERSIS TENCE LENGTH AND CATEGORIZE POLYMERS BY SHAPE. Elizabeth A. Conley 1575-Pos Board B528 ACCURATE PROTEIN FITTING INTO CRYO-EM MAPS USING MULTIPLE CONFORMERS GENERATED BY ALPHAFOLD2. Tatiana Shugaeva , nandan haloi, Rebecca J. Howard, Erik R. Lindahl 1576-Pos Board B529 QUANTIFYING BIOLOGICAL VARIABILITY USING APPROPRIATE DATA REPRESENTATIONS OF MICROSCOPY IMAGES. Ritvik Vasan , . Allen Institute for Cell Science, Julie Theriot, Matheus Palhares Viana, Susanne M. Rafelski 1577-Pos Board B530 FROM STATIC TO DYNAMIC: RAPID MAPPING OF PROTEIN CONFORMA TIONAL TRANSITIONS USING DEEPPATH. Yui Tik Pang , Lixinhao Yang, James C. Gumbart 1578-Pos Board B531 3D BARCODED RNA FISH WITH BAYESIAN UNCERTAINTY QUANTIFICA TION. Max Schweiger , Sina Jazani, Rory Kruithoff, Alexis Coullomb, Douglas P. Shepherd, Steve Pressé 1579-Pos Board B532 A NEAR-CONTINUUM MODEL OF MORPHODYNAMIC SINGLE-CELL STATES QUANTIFYING GENE EXPRESSION DURING EPITHELIAL-MESEN CHYMALTRANSITIONS. Jalim Singh , Jeremy T. Copperman, Ian McLean, Laura M. Heiser, Daniel M. Zuckerman 1580-Pos Board B533 DOCKING FOR MOLECULES THAT BIND IN A SYMMETRIC STACK TO ALZHEIMER’S DISEASE TAU FIBRILS WITH SYMDOCK. Matthew S. Smith , Peter Kunach, Ian S. Knight, Rian Kormos, Joseph G. Pepe, Isabella Glenn, John J. Irwin, William F. DeGrado, Marc I. Diamond, Sarah H. Shahmoradian, Brian K. Shoichet Single-Molecule Spectroscopy (Boards B534 - B559) 1581-Pos Board B534 PROCESSIVE DEGRADATION OF CELLULOSE BY THE BACTERIAL CEL LULASE TF CEL6B. Madeline M. Johnson , Antonio De Chellis, Bhargava Nemmaru, Shishir P.S. Chundawat, Matthew J. Lang 1582-Pos Board B535 ULTRAFAST, HIGH-ACCURACY DISEASE BIOMARKER DETECTION THROUGH FLUOROGENIC SINGLE MOLECULE RECOGNITION. Liu han Dai , Pavel Banerjee, Sujay Ray, Aaron T. Blanchard, Zi Li, Tewari Muneesh, Nils G. Walter 1583-Pos Board B536 ESTIMATE SINGLE-MOLECULE DIPOLE ORIENTATIONS WITH LOW-NU MERICAL APERTURE OPTICS IN A DUAL-VIEW GEOMETRY. Yonglei Sun , Quan Wang 1584-Pos Board B537 EXTENDING THE FORCE RANGE MEASURED BY AXIAL OPTICAL TWEE ZERS TO MEASURE THE BINDING STRENGTH OF G-PROTEIN COUPLED RECEPTORS. Zheng Zhang , Joshua Milstein 1585-Pos Board B538 EXPLORING THE RESOLUTION LIMITS OF SINGLE-MOLECULE FRET: COM PARING SURFACE-IMMOBILIZED AND FREE-SOLUTION APPROACHES IN AN ABEL TRAP. Lukas Whaley-Mayda , Yonglei Sun, Quan Wang

1586-Pos Board B539 SINGLE-MOLECULE QUANTIFICATION OF HUMAN ΑΒ-TUBULIN BIND ING KINETICS AT MICROTUBULE PLUS- AND MINUS-ENDS. Saradamoni Mondal 1587-Pos Board B540 RNA POLYMERASE ALONE SENSES DNA DOUBLE-STRAND BREAKS AND GENERATES R-LOOPS DURING TRANSCRIPTION. Gun Hyoung Lim , Seungha Hwang, Kilwon Yu, Jin Young Kang, Changwon Kang, Sungchul Hohng 1588-Pos Board B541 DEEP-LEARNING ASSISTED SINGLE-MOLECULE FRET ANALYSES ESTAB LISHED USING DNA ORIGAMI STRUCTURES. Pooyeh Asadiatouei , Simon Wanninger, Johann Bohlen, Clemens-Bässem Salem, Philip Tinnefeld, Evelyn Ploetz, Don C. Lamb 1589-Pos Board B542 AN EASY AND RELIABLE WAY TO PERFORM SINGLE MOLECULE FRET MEASUREMENTS. Evangelos Sisamakis, Isabel Groß, Marcelle Koenig , Maria Loidolt-Krueger, Fabio Barachati, Matthias Patting, Marcus Sack row, Kamil Bobowski, Mathias Bayer, Uwe Ortmann, Valentin Reiter Scherer, Felix Koberling, Rainer Erdmann 1590-Pos Board B543 STOCHASTIC LANGEVIN SIMULATIONSFOR TIME-RESOLVED CONFOCAL SMFRET EXPERIMENTS. David L. Frost, Keisha J. Cook, Hugo Sanabria 1591-Pos Board B544 OPTICAL TRAPPING ASSAYS TO STUDY FORCE-DEPENDENT MOBILITY OF THE DIFFUSING MICROTUBULE ASSOCIATED PROTEINS. Fedor Balabin , Vladimir Demidov, Fazly I. Ataullakhanov, Ekaterina L. Grishchuk 1592-Pos Board B545 A HIGH-THROUGHPUT CORRELATIVE MAGNETIC TWEEZERS - TIRF ASSAY TO INVESTIGATE PROTEIN-NUCLEIC ACIDS INTERACTIONS. M.Sadegh Feiz , Yibulayin Wubulikasimu, Jelmer Cnossen, Flavia Stal Papini, Subhas C. Bera, Salina Quack, David Dulin 1593-Pos Board B546 ABEL-PIE: PULSED INTERLEAVED EXCITATION FOR HIGH-PRECISION MEASUREMENTS OF SINGLE-MOLECULE PROTEIN-PROTEIN INTERAC TIONS. Ayesha Ejaz, Kavya Vaidya , Kyle Lin, Diangen (Dana) Lin, Jiachong Chu, David A. Drummond, Allison Squires 1594-Pos Board B547 RECENT ADVANCES IN TETHER-FREE SINGLE-MOLECULE SENSING WITH ANTI-BROWNIAN TRAPPING. Quan Wang 1595-Pos Board B548 SINGLE-PARTICLE TRACKING FROM SINGLE-PHOTON BINARY FRAMES. Weiqing Xu , Nathan Ronceray, Aleksandra Radenovic, Steve Pressé 1596-Pos Board B549 STABLE PARTIAL-CLOGGING IN SOLID-STATE NANOPORES AND ITS EF FECT ON RESISTIVE PULSES. Matthew J. O’Donohue 1597-Pos Board B550 DISENTANGLING CONFORMATIONAL AND PHOTOPHYSICAL DYNAMICS IN SINGLE-MOLECULE FRET AND PIFE EXPERIMENTS WITH MULTIPA RAMETER PHOTON-BY-PHOTON HIDDEN MARKOV MODELING. Paul D. Harris , Eitan Lerner, Alessandra Narducci, Christian Gebhardt, Shimon Weiss, Thorben Cordes 1598-Pos Board B551 SINGLE-MOLECULE ANALYSIS OF FERRITIN CONFORMATIONAL DYNAM ICS AND KINETICS. Arman Yousefi , Saaman Zargarbashi, Graham J. Hick man, Mahya Assadipapari, Ze Zheng, Gabriel Sanderson, Christopher D.J. Parmenter, Lei Xu, Mohsen Rahmani, Cuifeng Ying

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