BPS2024 Full Program & Abstracts

Symposium Best of Biophysical Journal: From Molecules to Systems 10:45 am - 12:45 pm, Room 103AB

1728-Plat 12:15 pm SHORT, DISORDERED N-TERMINI AND THE PROLINE-RICH REGION ARE MAJOR REGULATORS OF UBQLN1, UBQLN2 AND UBQLN4 PHASE TRAN SITIONS. Thuy P. Dao, Anitha Rajendran, Sarasi Galagedera, William Haws, Carlos A. Castaneda 1729-FlashTalk 12:30 pm DIMERIZATION-DEPENDENT GEL-LIKE CONDENSATION UNDERPINS ACTIVATION OF HUMAN CGAS. Jacob Lueck , Jungsan Sohn 1730-FlashTalk 12:35 pm CONTROLLED BY DISORDER: PROBING HOW THE PROTEIN SRSF1 IS ALTERED BY MODIFICATION OF ITS UNSTRUCTURED C-TERMINUS. Talia Fargason , Naiduwadura Ivon U. De Silva, Zihan Zhang, Trenton M. Paul, Jun Zhang 1731-FlashTalk 12:40 pm CHARACTERIZATION OF U1-70K’S LIQUID-LIQUID PHASE SEPARATION IN VITRO. Trenton M. Paul , Talia Fargason, Jun Zhang Platform Protein Assemblies 10:45 am - 12:44 pm, Room 201AB Co-Chairs Elizabeth Draganova, Emory University, USA Ed Partlow, NIH, USA 1732-Plat 10:45 am MODIFICATION AND RECOGNITION OF CHROMATIN BY DNA DAMAGE RESPONSE PROTEINS. Georges Mer , Maria Victoria Botuyan 1733-Plat 11:00 am A SMALL ADAPTOR PROTEIN CONTROLS PACKAGING AND MECHANI CAL PROPERTIES OF MUCIN GRANULES. Emilios K. Dimitriadis , Liping Zhang, Kayla J. Muirhead, Zulfeqhar Ali Syed, Kelly Ten Hagen 1734-Plat 11:15 am STRUCTURAL CHARACTERIZATION OF A UNIVERSAL SUPPRESSOR MUTA TION IN THE HSV-1 NUCLEAR EGRESS COMPLEX OLIGOMERIC LATTICE. Elizabeth B. Draganova , Hui Wang, Melanie Wu, Shiqing Liao, amber Vu, Gonzalo L. Gonzalez-Del Pino, Hong Zhou, Richard J. Roller, Ekaterina Travel Award Winner PROBING THE DISSOCIATION AND REASSEMBLY PATHWAY OF AN am Y LOIDOGENIC HOMOTETRAMER. Xun Sun , James A. Ferguson, Benjamin I. Leach, Robyn L. Stanfield, Jane Dyson, Peter E. Wright 1736-Plat 11:45 am MECHANISM OF TEMPLATED ASSEMBLY OF THE MAMMALIAN OR THOREOVIRUS CAPSID. Ed Partlow , Tijana Ivanovic 1737-Plat 12:00 pm THE NEGATIVE DESIGN PRINCIPLES OF HETERO-OLIGOMERIC FERRITIN ASSEMBLY REVEALED BY CRYO-EM AND GRAPH-THEORY ANALYSIS. Gabriel A. Frank , Daniel Stein, Bruno J. Jartoux, Shiran Dror, Ran Zalk, René Uebe, Raz Zarivach 1738-Plat 12:15 pm Travel Award Winner COOPERATIVITY AND INDUCED OLIGOMERISATION CONTROL THE INTERACTION OF SARS-COV-2 WITH ITS CELLULAR RECEPTOR AND PATIENT-DERIVED ANTIBODIES. Roi Asor , Anna Olerinyova, Sean A. Bur nap, Manish S. Kushwah, Mario Hensen, Snežana Vasiljevic, Liu Chang, Wanwisa Dejnirattisa, Piyada Supasa, David I. Stuart, Gavin R. Screaton, Nicole Zitzmann, Justin L.P. Benesch, Weston B. Struwe, Philipp Kukura Heldwein 1735-Plat 11:30 am

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Chair Vasanthi Jayaraman, University of Texas Health Science Center at Hous ton, USA No Abstract 10:45 am INTEGRIN Α IIB Β 3 INTERMEDIATES: FROM MOLECULAR DYNAMICS TO ADHESION ASSEMBLY. Tamara Bidone No Abstract 11:05 am MRNA LIPID NANOPARTICLE PHASE TRANSITION. Rainer A. Böckmann No Abstract 11:25 am VAST HETEROGENEITY IN CYTOPLASMIC DIFFUSION RATES REVEALED BY NANORHEOLOGY AND DOPPELGÄNGER SIMULATIONS. Rikki M. Garner No Abstract 11:45 am ★ TRACK: INFERRED COUNTING AND TRACKING OF REPLICATING DNA LOCI. Seán M. Murray No Abstract 12:05 pm A LABEL-FREE LIGHT-SCATTERING METHOD TO RESOLVE ASSEMBLY AND DISASSEMBLY OF DNA NANOSTRUCTURES. Gregor Posnjak No Abstract 12:25 pm Paper of the Year-Early Career Investigator Award INFLUENCE OF THE EXTRACELLULAR DOMAIN SIZE ON THE DYNAMIC BEHAVIOR OF MEMBRANE PROTEINS. Erdinc Sezgin Platform Condensates: Physical Properties and Modeling I 10:45 am - 12:45 pm, Room 113AB Co-Chairs Carlos Castaneda, Syracuse University, USA Yohan Lee, The University of Texas at Austin, USA 1722-Plat 10:45 am EX VIVO PHASESCAN: MAPPING HIGH RESOLUTION, MULTIDIMEN SIONAL PHASE DIAGRAMS OF PHYSIOLOGICAL PROTEIN CONDENSATES. Tanushree Agarwal 1723-Plat 11:00 am Travel Award Winner BIOMOLECULAR CONDENSATES INTERACTING WITH MEMBRANES: WETTING, REMODELING, AND DAMAGE STABILIZATION. Agustín Man giarotti , Claudio Bussi, Macarena Siri, Nicky W. Tam, Leonel S. Malacrida, Maximiliano G. Gutierrez, Rumiana Dimova 1724-Plat 11:15 am LIGHTNING THE CONDENSATES: THE ELECTROCHEMICAL FUNCTIONS OF BIOMOLECULAR CONDENSATES. Yifan Dai 1725-Plat 11:30 am TRANSMEMBRANE COUPLING OF LIQUID-LIKE PROTEIN CONDENSATES. Yohan Lee , Sujin Park, Feng Yuan, Carl C. Hayden, Liping Wang, Eileen M. Lafer, Siyoung Choi, Jeanne C. Stachowiak 1726-Plat 11:45 am Travel Award Winner UNDERSTANDING THE IMPACT OF ISOELECTRIC amINO ACIDS ON BIO MOLECULAR CONDENSATE BEHAVIOR. Aaron K. Kidane 1727-Plat 12:00 pm CONTROLLED RECRUITMENT OF PARTICLES INTO BIOMOLECULAR CON DENSATES . Fleurie Kelley , Anas Ani, Yuchen Ma, Bridget Linders, Bruna Favetta, Yuwei Gu, Benjamin S. Schuster

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