BPS2024 Full Program & Abstracts

1801-Plat 5:00 pm DYNAMICS OF CHROMOSOME ORGANIZATION IN A MINIMAL BACTE RIAL CELL. Benjamin R. Gilbert , Zane R. Thornburg, Troy A. Brier, Jan A. Stevens, Fabian Grunewald, John E. Stone, Siewert J. Marrink, Zaida Luthey-Schulten 1802-Plat 5:15 pm LANDSCAPES OF GENOMIC ARCHITECTURE ACROSS EVOLUTION. Mi chele Di Pierro 1803-Plat 5:30 pm MOLECULAR KINETICS OF TRANSCRIPTION AND CHROMATIN MOBILITY DURING EMBRYONIC DEVELOPMENT. Apratim Mukherjee , Kareena Shankta, Raymond D. Carter, Yara Haloush, Puttachai Ratchasanmuang, Mustafa Mir 1804-FlashTalk 5:45 pm ARCHITECTURE OF THE HUMAN KINETOCHORE ON INTACT MITOTIC CHROMOSOMES. Kathryn Kixmoeller , Yi-Wei Chang, Ben E. Black 1805-FlashTalk 5:50 pm CENTROMERE AND TELOMERE DYNAMICS REVEAL HETEROGENEITY OF THE HUMAN CELL NUCLEUS. Alexis Clavijo , Steven Ionov, Alexandra Zidovska 1806-FlashTalk 5:55 pm PROTEIN SEARCH PROCESSES MEDIATED BY CHROMATIN TOPOLOGY. Shuvadip Dutta , Ranjith Padinhateeri, Mithun K. Mitra Platform Co-Chairs Kaori Sugihara, The University of Tokyo, Japan Stephanie Tristram-Nagle, Carnegie Mellon University, USA 1807-Plat 4:00 pm Travel Award Winner MEMBRANE COMPOSITION AFFECTS BINDING AND INSERTION OF THE INFLUENZA VIRUS FUSION PEPTIDE. Melanie A. Brunet , Mary L. Kraft, Taras V. Pogorelov 1808-Plat 4:15 pm CHARACTERISATION OF ANTIMICROBIAL PEPTIDE INTERACTIONS WITH A REALISTICALLY PHASE SEPARATED MODEL OF THE E. COLI OUTER MEMBRANE VIA LARGE-SCALE SIMULATIONS. Dheeraj Prakaash , Alex andre B. González, Fergus Waterhouse, Syma Khalid 1809-Plat 4:30 pm Travel Award Winner CANDIDALYSIN PRE-PORE ASSEMBLY IN SOLUTION IS UNDER KINETIC CONTROL. Charles M. Russell , Katherine G. Schaefer, Robert J. Pyron, Gavin King, Francisco N. Barrera 1810-Plat 4:45 pm BIOPHYSICAL STUDIES OF NOVEL ANTIMICROBIAL PEPTIDES PERTURB ING BACTERIAL AND EUKARYOTIC LIPID MODEL MEMBRANES. Saheli Mitra, Mei-Tung Chen, Yunshu Li, Francisca Stedman, Rachel Koenig, Ian Daugherty, Grace Tang, Frank Heinrich, Stephen Hall, Berthony Des louches, Stephanie Tristram-Nagle 1811-Plat 5:00 pm INSERTION AND ANCHORING OF HIV-1 FUSION PEPTIDE INTO COMPLEX MEMBRANE MIMICKING THE HUMAN T-CELL. Mingfei Zhao , Chris Meale, Harshita Sahni, Anju Yadav, Tyler J.E. Reddy, Cesar A. Lopez, Sandrasegaram Gnanakaran 1812-Plat 5:15 pm DOUBLE COOPERATIVE EFFECT BETWEEN ANTIMICROBIAL PEPTIDES. Kaori Sugihara Membrane Active Peptides 4:00 pm - 6:00 pm, Room 204AB

1813-Plat 5:30 pm THE FUSION PEPTIDE OF THE INFLUENZA VIRUS SPIKE MEDIATES AG GREGATION, PORATION, AND MEMBRANE FUSION IN MEMBRANES WITH DIFFERENT COMPOSITIONS. Joshua Zimmerberg , amy Rice, Paul S. Blank, Glen Humphrey, Richard W. Pastor 1814-FlashTalk 5:45 pm INVESTIGATION OF THE SYNERGISTIC ANTIMICROBIAL EFFECT OF WINTER FLOUNDER PEPTIDES USING MOLECULAR DYNAMICS SIMULA TIONS. Miruna Serian , A. James Mason, Chris D. Lorenz 1815-FlashTalk 5:50 pm MECHANISM BY WHICH WATER INTERACTIONS STABILIZE A PH-DEPEN DENT MEMBRANE PORE. Ana-Nicoleta Bondar , Kalina Hristova, William C. Wimley 1816-FlashTalk 5:55 pm AMPHIPATHIC HELICES—SENSORS OF NEGATIVE MEMBRANE CURVA TURE? Peter Pajtinka , Robert Vacha Platform Ligand-Gated, Anion, and Other Channels II 4:00 pm - 6:00 pm, Room 201C Co-Chairs Toshimitsu Kawate, Cornell University, USA Megan Skains, Texas Tech Health Science Center, USA 1817-Plat 4:00 pm MECHANISM OF PANNEXIN 1 ACTIVATION BY C-TERMINAL CLEAV AGE. Erik K. Henze, Jacqueline Ehrlich, Janice L. Robertson, Toshimitsu Kawate 1818-Plat 4:15 pm Travel Award Winner FUNCTIONAL INSIGHTS INTO THE ACTIVITY OF CA 2+ CHANNELS RESPON SIBLE FOR THE GENERATION OF ACTION POTENTIALS IN THE MACRO PHYTE NITELLOPSIS OBTUSA . Vilmantas Pupkis , Indre Lapeikaite, Vilma 4:30 pm STRUCTURAL BASIS OF CLOSED GROOVE SCRAMBLING BY A TMEM16 PROTEIN. Zhang Feng , Omar E. Alvarenga-Cruz, Alessio Accardi 1820-Plat 4:45 pm Travel Award Winner INNATE PHOSPHOLIPID SCRAMBLASE CAPABILITY IN THE TMEM16 AND OSCA/TMEM63 FAMILIES. Augustus J. Lowry , Pengfei Liang, Yang Zhang, Yui Chun Serena Wan, Huanghe Yang 1821-Plat 5:00 pm STRUCTURAL DETERMINANTS OF LIGAND EFFICACY IN THE CALCIUM ACTIVATED CHLORIDE CHANNEL TMEM16A. Andy K.M. Lam , Raimund Dutzler 1822-Plat 5:15 pm FLUORIDE SELECTIVITY AND TRANSPORT MECHANISM IN NOVEL MI CROBIAL FLUORIDE CHANNELS AND ANTIPORTERS. Hedieh Torabifard 1823-Plat 5:30 pm QUESTIONING THE ROLE OF LRRC8A IN THE REGULATED VOLUME DECREASE (RVD) OF HUMAN KERATINOCYTES. Oliver Rauh , Magdalena Jahn, Claudia Bürger, Brigitte Hertel, Gerhard Thiel, Torsten Fauth 1824-FlashTalk 5:45 pm FROM HEAD TO TAIL - ATOMISTIC MECHANISM OF LONG-RANGE COUPLING FROM THE CYTOSOLIC SENSOR DOMAIN TO THE SELECTIVITY FILTER IN TREK K 2P CHANNELS. Marcus Schewe , Berke Türkaydin, Elena B. Riel, Friederike Schulz, Johann Biedermann, Thomas Baukrowitz, Han Sun Kisnieriene 1819-Plat

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