BPS2024 Full Program & Abstracts

1905-Pos Board B54 3D ANIMATION FOR INTEGRATIVE MODELING OF DYNAMIC MOLECU LAR MECHANISMS. Margot Riggi , Janet Iwasa 1906-Pos Board B55 Travel Award Winner STRUCTURE-GUIDED MUTATIONS OF THE UBIQUITIN CONJUGAT ING ENZYME UBCH5B IN ORDER TO STUDY A DOWNSTREAM COM PLEX. Maleesha D. Marakkala Manage 1907-Pos Board B56 CHOLESTEROL BLOCKS ONCOGENIC EPHA2 ACTIVITY & SELF-ASSEMBLY AS REVEALED BY SIMPULL-POP. Ryan J. Schuck , Alyssa Ward, Robert J. Pyron, Nick Trybala, Amita R. Sahoo, Matthias Buck, Joshua A. Baccile, Ioannis Sgouralis, Rajan Lamichhane, Francisco N. Barrera 1908-Pos Board B57 Travel Award Winner STRUCTURAL BASIS OF CLOSTRIDIUM PERFRINGENS ENTEROTOXIN AC TIVATION AND OLIGOMERIZATION BY TRYPSIN. Chinemerem P. Ogbu , Srajan Kapoor, Alex J. Vecchio 1909-Pos Board B58 OSMOLYTE INFLUENCE ON STABILITY AND OLIGOMERIZATION DYNAM ICS OF THE SACCHAROMYCES CEREVISIAE PCNA SLIDING CLAMP. Kaitlyn J. Parrott , Linda B. Bloom, Marcia Levitus 1910-Pos Board B59 ARCHITECTURAL BASIS FOR CYLINDRICAL SELF ASSEMBLY GOVERNING PLK4 MEDIATED CENTRIOLE DUPLICATION IN HUMAN CELLS. Harsha Ravi Shankar 1911-Pos Board B60 WEAK INTERACTIONS OF A PROTEIN HUB WITH TWO TRANSCRIPTION AL REGULATORS. Wallace Borden 1912-Pos Board B61 Travel Award Winner QUANTIFICATION OF MEMBRANE PROTEIN OLIGOMERIZATION IN NATIVE-LIKE MEMBRANE ENVIROMENTS BY SIMPULL-POP (SINGLE MOLECULE PULLDOWN -POLYMERIC-NANODISC OLIGOMER PHOTO BLEACHING). Alyssa Ward , Ryan J. Schuck, Rajan Lamichhane, Ioannis Sgouralis, Francisco N. Barrera 1913-Pos Board B62 Travel Award Winner LIPID MEMBRANE DAMAGE BY AMYLOID PEPTIDES: EFFECT OF THE POLAR/NON-POLAR SEQUENCE PATTERN. Warin Rangubpit , Jirasak Wong-Ekkabut, Cristiano L. Dias 1914-Pos Board B63 STRUCTURAL INSIGHTS INTO AN ACTINOBACTERIOPHAGE CAPSID: UN VEILING THE PROLATE HEAD STRUCTURE AND C-TERMINAL EXTENSION DOMAIN DYNAMICS THROUGH CRYO-EM AND MOLECULAR DYNAMICS SIMULATIONS. Andong Li , Eric R. May, Simon J. White 1915-Pos Board B64 PROGRESS TOWARD PROTEOME-WIDE PHOTO-CROSSLINKING MASS SPECTROMETRY TO INTERROGATE PROTEIN NETWORKS IN VIVO . An neliese M. Faustino , Stephen D. Fried 1916-Pos Board B65 A MULTISCALE COARSE-GRAINED MODEL OF HIV-1 CAPSID SELF-ASSEM BLY. Lorenzo Foglia , Alvin Yu 1917-Pos Board B66 Travel Award Winner A NANOSCOPIC MUCIN ASSEMBLY INHIBITION MODEL FOR IDENTIFI CATION AND DESIGN OF NOVEL MUCOLYTICS USING MASS PHOTOM ETRY. Nico Boback , Robyn Diehn, Cosmin Butnarasu, Daniel Lauster 1918-Pos Board B67 IMAGING NANOSCALE-SPATIAL OLIGOMERIC ORGANIZATION OF MEM BRANE PROTEINS DIRECTLY FROM NATIVE MEMBRANES AT SINGLE

MOLECULE RESOLUTION. Gerard Walker, Caroline Brown, Xiangyu Ge, Shailesh Kumar, Mandar Muzumdar, Kallol Gupta, Moitrayee Bhattacha ryya 1919-Pos Board B68 HOMOMERIC INTERACTIONS BETWEEN IG DOMAINS OF THE MPZ (P0) MYELIN ADHESION PROTEIN PROVIDE STRUCTURAL CONTEXT FOR MUL TIPLE DISEASE MECHANISMS. Christopher P. Ptak , Tabitha A. Peterson, Jesse B. Hopkins, Christopher A. Ahern, Michael E. Shy, Robert C. Piper Protein Dynamics and Allostery III (Boards B69 - B91) 1920-Pos Board B69 SYNTHESIS AND CHARACTERIZATION OF SARS-COV-2 MEMBRANE PROTEIN. Sara Anbir , Yuanzhong Zhang, Thomas E. Kuhlman, Pratyasha Mishra, Michael E. Colvin, Ajay Gopinathan, Umar Mohideen, Roya Zandi, Joseph McTiernan, Michael Worcester, Siyu Li 1921-Pos Board B70 COMPUTER-AIDED BIOSYNTHETIC PATHWAY ENGINEERING. Terra Sztain-Pedone 1922-Pos Board B71 IMPACT OF ENVIRONMENTAL FACTORS ON A METAMORPHIC PRO TEIN. Marie Pearce , Vincent J. Hilser 1923-Pos Board B72 Travel Award Winner GIRK CAHNNEL AS A REPORTER SYSTEM TO STUDY ALLOSTERY IN M2 MUSCARINIC ACETYLCHOLINE RECEPTOR. Pradeepti Kampani , Tapan K. Nayak 1924-Pos Board B73 INVESTIGATING THE DYNAMICS OF INTERLEUKIN-2 TOWARDS NOVEL TREG-BIASING IMMUNOTHERAPY DESIGN. Claire H. Woodward 1925-Pos Board B74 DO DIFFERENCES IN CRYPTIC POCKET OPENING CONTROL FUNCTIONAL TRADEOFFS IN FILOVIRUS IMMUNE EVASION? Upasana L. Malli madugula , Matthew A. Cruz, Maxwell I. Zimmerman, Kathleen B. Hall, Gregory R. Bowman 1926-Pos Board B75 BIOPHYSICAL APPROACHES TO UNDERSTAND METAL RETENTION IN QUED2 IN METAL STARVED ACINETOBACTER BAUMANNII. Emma McRae , David P. Giedroc 1927-Pos Board B76 FUNCTIONAL DISSECTION OF LIGHT- AND TEMPERATURE-SENSING OF BCLOV4 ENABLES GENERATION OF NOVEL PROBES FOR REMOTE CEL LULAR CONTROL. Zikang (Dennis) Huang , Lukasz Bugaj 1928-Pos Board B77 PARB PROMOTES DNA SLIDING AT THE C-TERMINAL DOMAIN THROUGH FLEXIBLE DNA BINDING LYSINE MOTIF. Aleksey Aleshintsev , HyeongJun Kim 1929-Pos Board B78 REAL-TIME OBSERVATION OF CAPSAICIN-INDUCED DOMAIN DYNAMICS OF TRPV1 USING THE DIFFRACTED X-RAY TRACKING METHOD. Kazuhiro Mio , Tatsunari Ohkubo, Hiroshi Sekiguchi, Yuji C. Sasaki 1930-Pos Board B79 A PARP2-SPECIFIC ACTIVE SITE ALPHA-HELIX MELTS UPON DNA DAM AGE-INDUCED ENZYMATIC ACTIVATION. Emily S. Smith , Ramya Billur, Marie-France Langelier, John Pascal, Ben E. Black

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