BPS2024 Full Program & Abstracts

2661-Pos Board B53 FROM DYNAMICS TO MECHANISMS: INSIGHTS INTO THE PH-DEPEN DENT BEHAVIOR OF NON-ENVELOPED VIRAL CAPSIDS VIA MOLECULAR DYNAMICS SIMULATIONS. Mahmoud Sharawy , Asis K. Jana, Eric R. May 2662-Pos Board B54 PROTEIN-PROTEIN INTERACTIONS OF COMPLEMENT PROTEINS C3 AND CFH. Debora Win , Amanda Streeter, Yakira Jack, Julia R. Koeppe 2663-Pos Board B55 NEURODEGENERATIVE VCP MUTANT AND WILD TYPE CO-ASSEMBLY AND STOICHIOMETRY ASSESSMENT BY SINGLE MOLECULE AS SAYS. Jingxuan Tang , Benjamin Dodd, Andreas Schmidt, Stephanie L. Moon, Nils G. Walter 2664-Pos Board B56 CHARACTERIZING THE EARLY STAGES OF FIBRIN FIBER ASSEMBLY VIA ATOMIC FORCE MICROSCOPY IMAGING. Weijun Gao , John Grubbs, Martin Guthold 2665-Pos Board B57 PRONOUNCED CHANGES IN ETC COMPLEX III ASSEMBLIES IN AN AGED MOUSE MODEL OF ALZHEIMERS DISEASE. Wenzhuo Ma , Clarissa Ca varsan Muller, Scarlett Huck, John Robinson, Richard T. Clements 2666-Pos Board B58 OPTOGENETIC PLATFORM FOR DISSECTING IRE1’S ENZYMATIC MECHA NISM. Swapnil Mukherjee , Vladislav Belyy 2667-Pos Board B59 INVESTIGATING THE AGGREGATION MECHANISM OF HUMAN CALCI TONIN AMYLOID THROUGH ITS LOW AGGREGATION-PRONE DOUBLE MUTATED VARIANT. Ling-Hsien Tu , Yu-Pei Chang 2668-Pos Board B60 INVESTIGATING A PREVIOUSLY UNIDENTIFIED INTERACTION BETWEEN VANS A AND VANZ IN VANCOMYCIN-RESISTANT ENTEROCOCCI. Nadia L. Hyatt , Grace Clark, Alanis Hernandez, Patrick J. Loll 2669-Pos Board B61 THE MINERALOCORTICOID RECEPTOR FORMS HIGHER ORDER OLIGO MERS UPON DNA BINDING. Gregory Fettweis, Thomas A. Johnson, Julián Weller-Pérez, Diego M. Presman, Gordon L. Hager, Diego Alvarez Travel Award Winner PTUA AND PTUB ASSEMBLE INTO AN INFLAMMASOME-LIKE OLIGOMER FOR ANTI-PHAGE DEFENSE. Xiaoyuan Yang 2671-Pos Board B63 FRET SPECTROMETRY AND MD SIMULATIONS-BASED MODELING RESOLVE THE OLIGOMERIC STRUCTURE OF A G PROTEIN-COUPLED RECEPTOR IN LIVE CELLS. Dammar N. Badu, Michael R. Stoneman , Ga briel Biener, Thomas D. Killeen, Kaleeckal G. Harikumar, Laurence Miller, Valerica Raicu 2672-Pos Board B64 ASSEMBLED STRUCTURES AND MECHANICAL IMPACTS OF EXTRACELLU LAR MATRIX PROTEIN COMPLEXES ON BIOMEMBRANES. Minh D. Phan , Sanjana Sureshbabu, Surabhi Singh, Sushil K. Satija, Norman J. Wagner 2673-Pos Board B65 THE NEGATIVE DESIGN PRINCIPLES OF HETERO-OLIGOMERIC FERRITIN ASSEMBLY REVEALED BY CRYO-EM AND GRAPH-THEORY ANALYSIS. Ga briel A. Frank , Daniel Stein, Bruno J. Jartoux, Shiran Dror, Ran Zalk, René Uebe, Raz Zarivach 2674-Pos Board B66 STRUCTURAL CHARACTERIZATION OF A UNIVERSAL SUPPRESSOR de la Rosa 2670-Pos Board B62

MUTATION IN THE HSV-1 NUCLEAR EGRESS COMPLEX OLIGOMERIC LATTICE. Elizabeth B. Draganova , Hui Wang, Melanie Wu, Shiqing Liao, Amber Vu, Gonzalo L. Gonzalez-Del Pino, Hong Zhou, Richard J. Roller, Ekaterina Heldwein 2675-Pos Board B67 Travel Award Winner COOPERATIVITY AND INDUCED OLIGOMERISATION CONTROL THE INTERACTION OF SARS-COV-2 WITH ITS CELLULAR RECEPTOR AND PATIENT-DERIVED ANTIBODIES. Roi Asor , Anna Olerinyova, Sean A. Bur nap, Manish S. Kushwah, Mario Hensen, Snežana Vasiljevic, Liu Chang, Wanwisa Dejnirattisa, Piyada Supasa, David I. Stuart, Gavin R. Screaton, Nicole Zitzmann, Justin L.P. Benesch, Weston B. Struwe, Philipp Kukura 2676-Pos Board B68 MECHANISM OF TEMPLATED ASSEMBLY OF THE MAMMALIAN OR THOREOVIRUS CAPSID. Ed Partlow , Tijana Ivanovic Membrane Protein Structures II (Boards B69 - B83) 2677-Pos Board B69 Travel Award Winner DECIPHERING SIGNAL SELECTIVITY OF GS AND GI IN MELATONIN RECEP TORS. Hiroyuki Okamoto 2678-Pos Board B70 STRUCTURAL BASIS OF ALLOSTERIC MODULATION OF METABOTROPIC GLUTAMATE RECEPTOR ACTIVATION AND DESENSITIZATION. Alexa Strauss , Alberto J. Gonzalez-Hernandez, Joon Lee, Nohely Abreu, Purushotham Selvakumar, Leslie Salas-Estrada, Melanie Kristt, Dagan C. Marx, Kristen Gilliland, Bruce J. Melancon, Marta Filizola, Joel Meyerson, Joshua Levitz 2679-Pos Board B71 SELENOPROTEIN S: DECIPHERING THE FUNCTION IN ENDOPLASMIC RE TICULUM STRESS RESOLUTION. Masha Kapitonova , Fabio A. Gonzalez Arias, Samiran Subedi, Sharon Rozovsky 2680-Pos Board B72 MOLECULAR MECHANISMS OF MEMBRANE-SHAPING PROTEINS ON THE ENDOPLASMIC RETICULUM. Buyan Pan 2681-Pos Board B73 PROBING THE TERTIARY STRUCTURE AND TOPOLOGY OF CAVEOLIN-1 IN BICELLES. Katrina Brandmier , Wonpil Im, Kerney Jebrell Glover 2682-Pos Board B74 NMR STUDIES OF THE COMPLEX BETWEEN THE SMALL GTPASE ARF1 AND SEGMENTALLY LABELED ARFGAP ASAP1 AT THE MEMBRANE SURFACE OF NANODISCS. Rebekah Jackson , Olivier Soubias, Brianna M. Papoutsis, Jess Li, Yue Zhang, Robert A. Byrd 2683-Pos Board B75 EXPLOITATION OF SINGLE-MOLECULE SENSING BY USING A SERIES OF MUTANT AEROLYSIN NANOPORES. Jun-Ge Li , Hongyan Niu, Jie Jiang, Meng-Yin Li, Yi-Tao Long 2684-Pos Board B76 CIRCULARIZED NANODISCS TO CHARACTERIZE MEMBRANE PORE FOR MATION. Huan Bao 2685-Pos Board B77 DEVELOPMENT AND APPLICATION OF NANODISCS FOR EPR STUDIES OF MEMBRANE-BOUND INFLUENZA A M2 PROTEIN. Caleb I. Porter , Kathleen P. Howard 2686-Pos Board B78 HEMAGGLUTININ SURFACE DENSITY IMPOSES FITNESS TRADEOFFS BE TWEEN VIRAL ATTACHMENT AND ANTIBODY NEUTRALIZATION. Ananya Benegal , Yuanyuan He, Zijian Guo, Kaitlyn Ho, Giselle Groff, Michael Vahey

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