BPS2024 Full Program & Abstracts

Natalia Santos, Trinity University MOLECULAR DYNAMICS SIMULATIONS TO INVESTIGATE PROTEIN FOLDING OF CROSS-SEEDED TAU AND AMYLIN IN ALZHEIMER’S DISEASE 1162-Pos, B115 Nadia Sarfraz, Georgetown University ADVANCING RNA VISUALIZATION: RIBOGLOW-FLIM UNVEILS INSIGHTS FOR MULTICELLULAR SYSTEMS 2031-Pos, B180 Andrew Savinov, Massachusetts Institute of Technology HIGH-THROUGHPUT DISCOVERY OF INHIBITORY PROTEIN FRAGMENTS WITH ALPHAFOLD 264-Pos, B30 Mariya Savinov, New York University FRICTION, NOT MYOSIN, DIRECTS ACTIN NETWORK CONTRACTION 2598-FlashTalk 3023-Pos, B415 Silvia Scalisi, University of Catania, Italy ORIGIN AND EVOLUTION OF ONCOGENE-RELATED DNA DAMAGE: A CONFOCAL IMAGING STUDY 1621-Pos, B574 Elizabeth H Schneider, University of Tennessee Health Science Center CHOLESTEROL BINDING TO THE ALPHA SUBUNIT OF LARGE CONDUCTANCE, CALCIUM- AND VOLTAGE-GATED POTASSIUM CHANNELS 1749-FlashTalk 2945-Pos, B337 Abigail Schroeter, University of Chicago USING HDX-MS TO PROBE THE DYNAMICS AND FREE ENERGY SURFACE OF GLPG, A HELICAL MEMBRANE PROTEIN 941-Plat 356-Pos, B122 Samantha R Schwarz, State University of New York at Buffalo ELUCIDATING THE GATING MECHANISMS OF DISEASE-RELATED GLUN1 TARGETING ANTI-AGGREGATION AND ANTI-OXIDATION OF AMYLOID DEPOSITS FOR THERAPEUTIC INTERVENTION OF ALZHEIMER’S USING MACHINE LEARNING ENHANCED MOLECULAR DOCKING 2327-Pos, B476 Karly B Serrano, Fisk University THE THERMODYNAMIC STABILITY AND MISFOLDING OF S100A12 2729-Pos, B121 Luke K Shafik, Georgetown University FLUORESCENCE LIFETIME IMAGING MICROSCOPY (FLIM) FOR DETECTION OF RNA ALTERNATIVE SPLICING IN LIVE CELLS 2025-Pos, B174 Ummay Mahfuza Shapla, University of Wisconsin-Madison SENSITIVITY ENHANCEMENT IN BIOMOLECULAR NMR:CHARACTERIZATION AND OPTIMIZATION OF LC-PHOTO-CIDNP FOR THE STRUCTURAL ANALYSIS OF PROTEINS IN SOLUTION 2336-Pos, B485 Y647 VARIANTS 2954-Pos, B346 Luthary Segura, Trinity University, Ireland

Tej K Sharma, Florida International University INVESTIGATING THE EFFECTS OF CTD MUTATIONS AS PLASMA MEMBRANE ASSOCIATION OF THE MARBURG VIRUS PROTEIN VP40 2508-FlashTalk 2610-Pos, B2 Kai R Sheng, The Scripps Research Institute AUGMENTING THE BACTERIAL RIBOSOME ASSEMBLY STRUCTUROME USING ANTI-SENSE OLIGONUCLEOTIDE ANALOGS 2002-Pos, B151 Tong Shu, New York University MESOSCALE MOLECULAR ASSEMBLY IS FAVORED BY THE ACTIVE, CROWDED CYTOPLASM 2756-Pos, B148 Sydney O Shuster, Yale University MULTISPECTRAL VIBRATIONAL IMAGING FOR HIGH RESOLUTION TRACKING OF LIVE CELL METABOLIC PROCESSES 2513-Plat 798-Pos, B564 Shannon Sim, McGill University, Canada γ-TUBULIN ORCHESTRATES EARLY EVENTS IN MITOSIS THAT STABILIZE NASCENT BIPOLAR SPINDLES 1501-Pos, B454 Macarena Siri, Max Planck Institute of Colloids and Interfaces, Germany AMYLOID FIBERS IN BIOFILMS: STRUCTURE AND ADAPTATION TO ENVIRONMENTAL CUES 185-Plat 2739-Pos, B131 Tomasz Skóra, University of Utah BOTTOM-UP COARSE-GRAINED MODEL OF MICROTUBULE DYNAMICS: A BRIDGE BETWEEN LENGTH- AND TIMESCALES 1503-Pos, B456 Ally K Smith, University of Maryland, Baltimore GENERATING IN SILICO PROTEIN STRUCTURAL ENSEMBLES THAT AGREE WITH SOLUTION-BASED EXPERIMENTS: AN HDX-MS-STEERED ADAPTIVE SAMPLING APPROACH FOR MOLECULAR DYNAMICS 2383-Pos, B532 Quentin M Smith, Imperial College London STRUCTURAL BASIS OF NEGATIVE SUPERCOILING INDUCED CAS9 OFF TARGETING 1767-Plat 2811-Pos, B203 Ben Sorum, University of California, Berkeley QUANTIFYING TENSION GENERATED BY MECHANICAL FORCE IN TWO PORE-DOMAIN K+ (K2P) CHANNELS 2599-Plat Kerri Spontarelli, Texas Tech University Health Sciences Center FUNCTIONAL EVALUATION OF A CMT2DD-CAUSING ATP1A1 VARIANT 2231-Pos, B380

XXI