BPS2024 Full Program & Abstracts

Postdoctoral Breakfast Securing Fellowships: Pathway to Independence 7:30 am - 8:30 am, Room 111AB Being a postdoc is not easy and there can be many challenges along the way. This breakfast presents an opportunity for postdoctoral Annual Meeting attendees to meet and discuss the issues they face in their cur rent career stage. Attendees will have the opportunity to hear and learn from speakers who will share their journeys, experiences, and success stories. Limited to the first 100 attendees. Moderators Harpreet Singh, The Ohio State University, USA Christian Jorgensen, Portsmouth University, United Kingdom Trushar Patel, University of Lethbridge, Canada Registration/Exhibitor Registration 7:30 am - 5:00 pm, Registration Bridge West Poster Viewing 8:00 am - 10:00 pm, Exhibit Hall AB Symposium Phase Separation in Membrane and Lipids 8:15 am - 10:15 am, Ballroom A Chair Abdou Rachid Thiam, École Normale Supérieure (ENS), France 41-Symp 8:15 am KINETIC FRUSTRATION CONTROLS MEMBRANE-BOUND PROTEIN CON DENSATES. Simou Sun, Trevor GrandPre , David Limmer, Jay Groves 42-Symp 8:40 am THE MEMBRANE PHASE TRANSITION SHAPES B CELL RECEPTOR SIGNAL ING DOMAINS. Sarah Shelby , Sarah L. Veatch 43-Symp 9:05 am PHASE SEPARATION REGULATES INTEGRIN RECEPTOR CLUSTERING AND DOWNSTREAM SIGNALING. Lindsay Case 44-SympSelect 9:30 am HIGH INTERFACIAL TENSION OF LIPID DROPLETS DISRUPTS THE NU CLEUS, CYTOSKELETON, AND MOTILE FUNCTIONS. Irena L. Ivanovska, Michael P. Tobin, Dennis E. Discher No Abstract 9:50 am CHOLESTEROL PACKAGING INTO LIPID DROPLETS. Abdou Rachid Thiam Symposium New Approaches to Capture the Central Dogma in Eukaryotes 8:15 am - 10:15 am, Ballroom B Chair Xiaowei Zhuang, Harvard University, USA 45-Symp 8:15 am SINGLE MOLECULE IMAGING OF ENDOGENOUS TRANSCRIPTION AND TRANSLATION. Timothy J. Stasevich , O'Neil Wiggan, Tatsuya Morisaki, Matthew N. Saxton 46-Symp 8:40 am EXPANDING TAGGING TOOLBOX FOR VISUALIZING TRANSLATION LIVE. Ning Zhao , Timothy J. Stasevich

No Abstract 9:05 am UNCOVERING HOMOLOGOUS CHROMOSOME COMMUNICATION. Jumana AlHaj Abed 47-SympSelect 9:30 am LANTHANIDE CATHODOPHORES FOR MULTICOLOR ELECTRON MICROS COPY. Maxim B. Prigozhin , Sohaib Abdul Rehman, Jeremy Conway No Abstract 9:50 am SPATIALLY RESOLVED SINGLE-CELL GENOMICS AND CELL ATLAS OF THE BRAIN. Xiaowen Zhuang Platform Molecular Dynamics I 8:15 am - 10:15 am, Room 103AB Co-Chairs Gianmarco Lazzeri, Frankfurt Institute for Advanced Studies, Germany Justin Lemkul, Virginia Tech, USA 48-Plat 8:15 am MORE WITH LESS: HARVESTING TRANSITION MECHANISM, FREE ENERGY, AND RATES FROM SHORT PARALLEL MOLECULAR DYNAM ICS SIMULATIONS. Gianmarco Lazzeri , Hendrik Jung, Peter G. Bolhuis, Roberto Covino 49-Plat 8:30 am UTILITY OF A TIME-LAGGED AUTOENCODER FOR CALCULATING FREE ENERGY BY GENERATING A LARGE NUMBER OF SYNTHETIC TRAJECTO RIES BASED ON MOLECULAR DYNAMICS. Soheil Jamali , Fauzia Haque, Mahmoud Moradi 50-Plat 8:45 am HOW TO GET YOUR ACT TOGETHER: A SEQUENCE AGNOSTIC METHOD FOR TRANSITION PATH SAMPLING WHEN TARGET STATES ARE NOT KNOWN. Yoo Jin C. Sheen , Michael Grabe, John M. Rosenberg 51-Plat 9:00 am SYNERGISTIC APPROACHES TO ELUCIDATION OF ENZYME MECHA NISMS/DYNAMICS. Mikaela Farrugia , Olaf Wiest, Paul Helquist 52-Plat 9:15 am COMPARATIVE STUDY OF IM7 DYNAMICS: CHARMM36M VS DRUDE2019 FORCE FIELDS WITH NMR VALIDATION. Sangram Prusty , Rafael Brüschweiler, Qiang Cui 53-Plat 9:30 am SIMULATIONS OF LIQUID JET EXPLOSIONS AND SHOCK WAVES INDUCED BY X-RAY FREE-ELECTRON LASERS. Leonie Chatzimagas , Jochen S. Hub 54-Plat 9:45 am ELECTRIC FIELDS AND INDUCED POLARIZATION EFFECTS IN RNA: IMPLI CATIONS FOR FOLDING AND FUNCTION. Justin A. Lemkul 55-FlashTalk 10:00 am GRAND CANONICAL SIMULATIONS OF DISORDERED PROTEINS. Rodrigo Travel Award Winner IN SILICO ANALYSES OF MOLECULAR FORCE SENSORS FOR MECHANICAL CHARACTERIZATION OF BIOLOGICAL SYSTEMS. Diana L. Lopez , Marcos M. Sotomayor, Carlos E. Castro 57-FlashTalk 10:10 am K-MEANS CLUSTERING COARSE-GRAINING (KMC-CG): A NEXT GENERA TION METHODOLOGY FOR DETERMINING OPTIMAL COARSE-GRAINED MAPPINGS OF LARGE BIOMOLECULES. Jiangbo Wu , Weizhi Xue, Gregory A. Voth F. Dillenburg 56-FlashTalk 10:05 am

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