BPS2024 Full Program & Abstracts

366-Pos Board B132 COOPERATIVE HETEROTYPIC INTERACTIONS OF PRION-LIKE LOW COMPLEXITY DOMAINS DRIVE CO-CONDENSATION OF FET PROTEINS AND CHROMATIN REMODELER MSWI/SNF COMPLEX. Richoo B. Davis , Anushka Supakar, Priya R. Banerjee 367-Pos Board B133 EFFECTS OF PHOSPHORYLATION ON THE DISORDERED RNA POLY MERASE II CTD DOMAIN LOCAL AND GLOBAL CONFORMATION. William Barr , Raymond B. East, Wei Chen, Scott A. Showalter, K. Aurelia Ball 368-Pos Board B134 STRUCTURE DETERMINATION OF AMYLOID-Β OLIGOMERS (40-, 42-RESI DUES) WITH ALPHAFOLD2. Gideon S. Mitchell , Esmael J. Haddadian 369-Pos Board B135 ESTABLISHING THE ROLE OF PHOSPHORYLATION IN HEPATITIS B VIRUS NUCLEOCAPSID RECOGNITION BY HUMAN IMPORTINS. Juan F. Marin , Santiago Antolinez, Carolina Pérez Segura, Jodi A. Hadden-Perilla 370-Pos Board B136 Travel Award Winner SINGLE-MOLECULE SPECTROSCOPY OF THE SARS-COV-2 NUCLEOCAPSID PROTEIN. Jasmine Cubuk , J. Jeremias Incicco, Melissa D. Stuchell-Brere ton, Kathleen B. Hall, Andrea Soranno 371-Pos Board B137 THE MATERIAL PROPERTIES AND CROSSTALK BETWEEN TAU AND ALPHA-SYNUCLEIN CONDENSATES. Bineet Sharma , Jean Baum, Zheng Shi 372-Pos Board B138 DECIPHERING THE FUZZY INTERACTIONS IN THE NUCLEAR TRANSPORT ER. Arpita Tawani , Shuo Qian, Samuel Sparks, Michael P. Rout, David Board B139 CIRCULAR DICHROISM STUDY OF LATE EMBRYOGENESIS ABUNDANT PEPTIDES: EFFECTS OF DRYING, SALT, AND TRIFLUOROETHANOL. Jorge Carmona , Emma Route, Catherine Fairfield, Michelle R. Bunagan 374-Pos Board B140 QUANTIFYING TAU-MICROTUBULE INTERACTIONS WITH TIRF MICROS COPY AND FCS. Polina Holubovska , Karen Acosta 375-Pos Board B141 PROTEINS IN PHASE: UNVEILING THE ROLE OF IDPS AND STRUCTURED PROTEINS IN BIOMOLECULAR CONDENSATES. Arjun Singh , Gregory Dignon 376-Pos Board B142 CIRCULAR DICHROISM CHARACTERIZATION OF LATE EMBRYOGENESIS ABUNDANT PEPTIDES IN RESPONSE TO SALTS, TEMPERATURE, AND REDUCED HYDRATION. Michelle R. Bunagan , Melvin Paulose, Stephen Schmidt, Kyle Barrie 377-Pos Board B143 TOWARDS EXPERIMENTALLY PARAMETRIZED MOLECULAR DYNAMICS FORCE FIELD FOR INTRINSICALLY DISORDERED PROTEINS. Athul Suresh , Reinhard Schweitzer-Stenner, Brigita Urbanc 378-Pos Board B144 PHOTO-INDUCED ELECTRON TRANSFER EXPERIMENTS PROBING IN TRINSICALLY DISORDERED PROTEIN DYNAMICS: EFFECT OF DANGLING ENDS. Crystal F. Ottoway , Gabor Nagy, Wenwei Zheng, Gerdenis Kodis, Aaron Globisch, Helmut Grubmüller, Sara M. Vaiana 379-Pos Board B145 OLIGOMER FORMATION BY NATURALLY OCCURRING C-TERMINAL ISO FORMS OF AMYLOID Β -PROTEIN. Rachit Pandey , Brigita Urbanc Cowburn 373-Pos

380-Pos Board B146 PRION PROTEIN-DERIVED CELL-PENETRATING PEPTIDE INHIBITS TYPE II DIABETES ASSOCIATED ISLET AMYLOID POLYPEPTIDE AGGREGATION AND CYTOTOXICITY. Yujeong Oh , Madeline Howarth, Palanikumar Loganathan, Debabrata Maity, Morad Mustafa, Sunil Kumar, Mazin M. Magzoub 381-Pos Board B147 DNA BINDING REDISTRIBUTES ACTIVATION DOMAIN ENSEMBLE AND ACCESSIBILITY IN PIONEER FACTOR SOX2. Sveinn Bjarnason, Jordan McIvor, Andreas Prestel, Kinga Demeny, Jakob Bullerjahn, Birthe B. Kragelund, Davide Mercadante, Petur O. Heidarsson 382-Pos Board B148 TDP-43 PROMOTES AMYLOID-BETA TOXICITY BY DELAYING FIBRIL MATU RATION VIA DIRECT MOLECULAR INTERACTION. Adam J. Gatch , Feng Ding 383-Pos Board B149 DECOUPLING SEQUENCE AND CONFORMATIONAL DETERMINANTS OF STRONG IDP BINDERS TO INFORM THERAPEUTIC INTERVENTION. Bryan A. Bogin , Zachary A. Levine 384-Pos Board B150 SEGMENTS OF A DISORDERED PEPTIDE DIFFERENTIALLY INTERACT WITH AN SH3 DOMAIN. M. Adriana Cuibus , Raymond B. East, Elliott J. Stollar, K. Aurelia Ball 385-Pos Board B151 CONCENTRATION DEPENDENCE OF AGGREGATION PATHWAYS DURING AΒETA42 AGGREGATION REVEALED BY SINGLE MOLECULE FRET IMAG ING AND DEEP LEARNING. Sara Sohail , Janghyun Yoo, Hoi Sung Chung 386-Pos Board B152 SYNERGY BETWEEN THE STRUCTURED AND DISORDERED REGIONS OF ΑLPHA-SYNUCLEIN IN MEMBRANE REMODELING. David H. Johnson , Wade F. Zeno 387-Pos Board B153 HIGH-THROUGHPUT QUANTITATIVE CHARACTERIZATION OF CELLU LAR IDR PHASE BEHAVIOR OUT OF EQUILIBRIUM USING A SYNTHETIC REACTION-DIFFUSION PROBE. Chih-Chia Chang , Zhejing Xu, Elliott W.Z. Weix, Scott M. Coyle 388-Pos Board B154 PHASE SEPARATION OF E.COLI SSB IS ACCOMPANIED BY PROTON UP TAKE. Alexander G. Kozlov , Timothy M. Lohman 389-Pos Board B155 CHARACTERIZATION OF ANDROGEN RECEPTOR PROPERTIES IN MEDIAT ING TRANSCRIPTIONAL BIOMOLECULAR CONDENSATES IN PROSTATE CANCER. Nicholas C. Pinette , Shabnam Massah, Tian Hao Huang, Sofia Kochkina, Alex Bembridge, Jane Foo, Maria Guo, Hanadi Ibrahim, Artem Cherkasov, Joerg Gsponer, Nada Lallous 390-Pos Board B156 PROTEOME-WIDE DNAK BINDING-SITES IN E. COLI AND MYCOBACTE RIUM TUBERCULOSIS . Sreemantee Sen , Edgar Manriquez-Sandoval, Sterling Sandler, Tania Lupoli, Stephen D. Fried 391-Pos Board B157 DECIPHERING THE MOLECULAR LANGUAGE OF FUS PHASE SEPARA TION. Shuo-Lin Weng , Jeetain Mittal 392-Pos Board B158 TARDIGRADE CAHS HYDROGELS PROTECT PROTEINS THROUGH CONCENTRATION-DEPENDENT MECHANISM. Marisa A. Barilla , Sydney O. Shuster, Caitlin Davis

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