BPS2024 Full Program & Abstracts

Membrane Receptors and Signal Transduction (Boards B287 - B318) 521-Pos Board B287 DISTINCT SPATIOTEMPORAL DYNAMICS OF CALMODULIN GENES IN CARDIAC MYOCYTES UNDER BETA-ADRENERGIC STIMULATION. Vladimir Bogdanov , Benjamin Hernandez Orengo, Juan Ignacio Elio Mariangelo, Casey Beard, Anastasiia Pokrass, Galina Sakuta, Andrew M. Soltisz, Svet lana Tikunova, Rengasayee Veeraraghavan, Jonathan P. Davis, Sandor Gyorke 522-Pos Board B288 CHEMOSENSORY SYSTEM REPROGRAMMING VIA QUATERNARY STRUC TURE REGULATION. Katherine Leon Hernandez , Colin D. Kinz-Thompson 523-Pos Board B289 COMPUTATIONAL MODELING UNVEILS NOVEL REGULATORY MECHA NISMS IN GQSIGNALING. Joshua Richard , Miguel Hernandez-Lara, Sushrut D. Shah, Deepak A. Deshpande 524-Pos Board B290 STRUCTURAL ELUCIDATION OF RXFP2 ALLOSTERIC AGONIST (COM POUND-6641) BINDING: A COMPUTATIONAL AND EXPERIMENTAL APPROACH. Abhijeet Kapoor , Maria Esteban-Lopez, Kenneth J. Wilson, Alexander I. Agoulnik, Mark J. Henderson, Juan J. Marugan 525-Pos Board B291 MITOCHONDRIA-ASSOCIATED RESTRICTED SPACES REGULATE COM PARTMENTALIZED CAMP SIGNALING IN ADULT VENTRICULAR MYO CYTES. Andrea B. Agarwal, Nisha Chouhan, Shailesh R. Agarwal 526-Pos Board B292 GPCR-MEDIATED Β-ARRESTIN ACTIVATION AND PLASMA MEMBRANE RECRUITMENT DECONVOLUTED WITH SINGLE-MOLECULE PRECI SION. Wesley B. Asher 527-Pos Board B293 EPITHELIAL PERMEABILITY IN THE EMBRYONIC MOUSE LUNG. Sonia Hasko , Samhita P. Banavar, Eric W. Fowler, Celeste M. Nelson 528-Pos Board B294 INVESTIGATION OF THE NEUROKININ RECEPTOR 1 STRUCTURES AND ITS REGULATION BY ITS ENDOGENOUS ACTIVATOR SUBSTANCE P AND THE ANTAGONIST APREPITANT. Eva-Maria Plessl , Theres Friesacher 529-Pos Board B295 EXPLORING CROSS-FAMILY ACTIVATION OF GROWTH FACTOR RECEP TORS WITH MOLECULAR DYNAMICS SIMULATIONS. Aaron Chan , Yingye Fang, Princess Imoukhuede, Emad Tajkhorshid 530-Pos Board B296 ATLAZ AS A HIGH-THROUGHPUT SYSTEM FOR ADVANCED FUNCTIONAL CELL ANALYSIS TO DEVELOP IMMUNOTHERAPIES. Ronald Knox , Marta Lemme, Martin Ziller, Max Engelstädter, Matthias Gossmann, Peter Linder, Bettina Lickiss, Elena Dragicevic, Johannes Stepper, Michael George, Niels Fertig, Sonja Stoelzle-Feix 531-Pos Board B297 EPITOPE ACCESSIBILITY AFFECTS B CELL RECOGNITION OF INFLUENZA VIRUS PROTEINS. Yuanyuan He 532-Pos Board B298 STOCHASTIC MODEL OF EXTRACELLULAR VESICLE-MEDIATED IMMUNO SUPPRESSION IMPLICATES IMPORTANCE OF BIOPHYSICAL PARAMETERS IN T-CELL SIGNALING. Seung-Hyun B. Ko , Ramakrishnan Natesan, Jina Ko, Ravi Radhakrishnan

533-Pos Board B299 STED MICROSCOPY AND SINGLE MOLECULE FRET TO UNCOVER MEMBRANE RECEPTOR - LIGAND INTERACTIONS IN APOPTOSIS SIGNAL INITIATION. Xiaoyue Shang , Cornelia Monzel 534-Pos Board B300 ALLOSTERIC COMMUNICATION ACROSS THE MU-OPIOID RECEPTOR-G I1 PROTEIN COMPLEX INDUCED BY LIGANDS OF VARYING EFFICACY. Bianca Fiorillo , Rikhia Ghosh, Kirill Konovalov, Davide Provasi, Marta Filizola 535-Pos Board B301 DRUG-RESISTANT EGFR LUNG CANCER MUTATIONS PROMOTE TUMOR GROWTH BY STABILIZING INTERFACES IN LIGAND-FREE SIGNALING COMPETENT EGFR OLIGOMERS. Sarah R. Needham , Sumanth Iyer, Benjamin M. Davis, Ioannis Galdadas, Selene K. Roberts, Laura C. Zanetti Domingues, David T. Clarke, Francesco L. Gervasio, Daniel J. Rolfe, Marisa Martin-Fernandez 536-Pos Board B302 UNIQUE ROLES OF FXYD3-HIGH CANCER STEM CELLS IN RADIO-RESIS TANCE. Masahiro Yamazaki , Mengjiao Li, Tatsunori Nishimura, Tsunaki Hongu, Shigeyuki Takamatsu, Toshifumi Gabata, Masaya Ueno, Atsushi Hirao, Susumu Kohno, Takahashi Chiaki, Kuniko Horie, Kazuhiro Ikeda, Satoshi Inoue, Noriko Gotoh 537-Pos Board B303 DISSECTING ER STRESS SIGNALING WITH LIVE-CELL SINGLE-MOLECULE IMAGING AND OPTOGENETICS. Swapnil Mukherjee, Jacob Smith, Vladislav Belyy 538-Pos Board B304 SOLID-STATE NMR REVEALS SIGNALING-RELATED CHANGES IN FUNC TIONAL CHEMOTAXIS RECEPTOR COMPLEXES. Jessica Allen , Songlin Wang, Riqiang Fu, Chad M. Rienstra, Lynmarie K. Thompson 539-Pos Board B305 STRUCTURAL BASIS OF DISTINCT SIGNALING KINETICS OF CALCITONIN LIKE RECEPTOR PEPTIDE LIGANDS. Katie Babin , Jordan Karim, Peyton Gordan, James Lennon, Alex Dickson, Augen A. Pioszak 540-Pos Board B306 SYNTHETIC T CELL RECEPTOR LIGANDS THAT MIMIC NATIVE PMHC LIGAND BINDING KINETICS. Brittany Stinger , Anand Vissa, Kiera B. Wilhelm, Jay T. Groves 541-Pos Board B307 ELUCIDATION OF A DYNAMIC INTERPLAY BETWEEN BETA-ADRENERGIC RECEPTORS, ITS AGONISTS AND STIMULATORY G PROTEIN. Yanxiao Han , John R.D. Dawson, Kevin DeMarco, Kyle Rouen, Khoa Ngo, Borislava Bekker, Vladimir Yarov-Yarovoy, Colleen E. Clancy, Yang K. Xiang, Surl-Hee Ahn, Igor V. Vorobyov 542-Pos Board B308 LINKING INSULIN RECEPTOR ACTIVATION TO HYDROPHOBIC MISMATCH USING TRANSMEMBRANE MUTATIONS. Antonio Torlentino , Pavana Suresh, Erwin London, W. Todd Miller 543-Pos Board B309 Travel Award Winner DECIPHERING THE MOLECULAR MECHANISMS OF STRA6-MEDIATED RETINOL TRANSPORT. Myongin Oh , Ekaterina D. Kots, Brianna Costabile, Aysenur T. Yazici, Filippo Mancia, George Khelashvili 544-Pos Board B310 CALCIUM IONS MODULATE THE ACTIVATION OF METABOTROPIC GLUTA MATE RECEPTOR BY GLUTAMATE. Sadaf Dadashkhan , Christian Sattler, Thomas Zimmer, Klaus Benndorf, Ralf Schmauder

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