BPS2024 Full Program & Abstracts

Membrane Pumps, Transporters, and Exchangers I (Boards B382 - B406) 616-Pos Board B382 THE SPECTRE OF CHLOROQUINE; EVOLUTIONARY CONFLICT AT THE MOLECULAR LEVEL IN A PLASMODIUM FALCIPARUM MULTIDRUG RESIS TANCE PROTEIN. John D. Tanner , Ben Corry 617-Pos Board B383 USING MONTE CARLO MICROSTATES TO FOLLOW PROTON TRANSPORT IN COMPLEX I. MD Raihan Uddin , Umesh Khaniya, Abhishek Singharoy, Chitrak Gupta, Marilyn Gunner 618-Pos Board B384 CA 2+ EFFLUX FACILITATED BY CO-TRANSPORT OF PHOSPHATE ANION IN H + /CA 2+ ANTIPORTER. Lei Zheng , Wei Niu, Vasanthi Jayaraman, José D. Faraldo-Gómez, Wenchang Zhou, SHUO LU, Trung Vu 619-Pos Board B385 Travel Award Winner DECIPHERING CONNEXIN 26 (CX26) HEMICHANNELS: BEYOND ION CONDUCTION, INTO MOLECULE TRANSPORT. Deepak Kumar , Pablo S. Gaete, Jorge E. Contreras, Yun Lyna Luo 620-Pos Board B386 Travel Award Winner A PROTON-TRANSFER MECHANISM IN THE MALARIA PARASITE LAC TATE/H + SYMPORTER SUGGESTS A TRANSPORTER WITHOUT CONFOR MATIONAL CHANGES. Ciara J.F. Wallis , Kasimir P. Gregory, Ruitao Jin, Sitong He, Adele M. Lehane, Ben A. Corry 621-Pos Board B387 TRANSPORT MECHANISMS OF DGOT, A BACTERIAL HOMOLOG OF ORGANIC ANION TRANSPORTERS. Nataliia Dmitrieva , Samira Gholami, Claudia Alleva, Mercedes Alfonso Prieto, Paolo Carloni, Christoph M. Fahlke 622-Pos Board B388 EXPLORING THE LINK BETWEEN DISEASE-CAUSING CLC-7 MUTATIONS AND LYSOSOMAL PH. Vedrana Mikusevic , Jacob K. Hilton, Reena Jethva, Andreas Janecke, Richard Steet, Joseph A. Mindell 623-Pos Board B389 EVOLUTION OF ENERGETIC BARRIERS IN THE SMR FAMILY. Trevor J. Yeh , Randy B. Stockbridge 624-Pos Board B390 FERROPORTIN INHIBITION BY PI(4,5)P2 AND CHOLESTEROL. Ce Liang , Yaping Pan, Arthur Laganowsky, Ming Zhou 625-Pos Board B391 STRUCTURAL MECHANISMS FOR VMAT2 INHIBITION BY TETRABENA ZINE. Michael P. Dalton , Mary H. Cheng, Ivet Bahar, Jonathan Coleman 626-Pos Board B392 ALCHEMICAL FREE ENERGY SIMULATIONS SUPPORT THE FORMATION OF THE SARCO-ENDOPLASMIC RETICULUM CALCIUM PUMP (SERCA) IN HIBITORY COMPLEX FROM THE PHOSPHOLAMBAN PENTAMER. Nishadh Rathod, Christophe J. Chipot, Benoit Roux, Howard S. Young 627-Pos Board B393 ASSEMBLY MECHANISM OF THE TWIN ARGININE TRANSPORTER. Mari ana R.B. Batista , Phillip J. Stansfeld 628-Pos Board B394 TRANSITION RATE ESTIMATION FROM ALONG-THE-PATH, UNBIASED, MOLECULAR DYNAMICS SIMULATIONS OF A MAJOR FACILITATOR SU PERFAMILY TRANSPORTER. Ashkan Ghaan , James Losey, Curtis Goolsby, Emad Tajkhorshid, Mahmoud Moradi

629-Pos Board B395 MOLECULAR DETERMINANTS OF INHIBITION OF UCP1-MEDIATED RESPIRATORY UNCOUPLING. Bruno Miroux , Antoine Gagelin, Corentin Largeau, Mathilde Piel, Sandrine Masscheleyn, Daniel Calderon-Mora, Frederic Bouillaud, Jérôme Hénin 630-Pos Board B396 NOVEL BACTERIAL MATE FAMILY TRANSPORTER IS INVOLVED IN METAL RESISTANCE. Achala Chittor , Sabrina Kolb, Randy Stockbridge 631-Pos Board B397 Travel Award Winner AUTOMATING COLLECTIVE VARIABLE DISCOVERY FROM MOLECULAR DYNAMICS SIMULATIONS USING MACHINE LEARNING. Maria Margarida Gil dos Santos Silva Rosa , Myongin Oh, George Khelashvili 632-Pos Board B398 HYPONATREMIC CONDUCTION SLOWING DURING CHANNEL LOSS OF FUNCTION IS MEDIATED BY HERG CURRENTS AND EPHAPTIC COU PLING. William P. Adams , Steven Poelzing, Gregory Hoeker, Biwar Z. Marof 633-Pos Board B399 REVEALING THE UNRESOLVED BINDING SITES AND OUTWARD-FACING STATE OF NACT. Noah Trebesch , Emad Tajkhorshid 634-Pos Board B400 SPELUNKING WITH POTASSIUM: FUNCTIONAL ANALYSIS OF THE WATER TUNNEL IN THE POTASSIUM PUMP KDPFABC. Adel K. Hussein , Xihui Zhang, Audri Wong, David L. Stokes 635-Pos Board B401 THE PHYSIOLOGY OF SEMINAL ZINC. Jennifer M. Miller , Rachel E. Bain bridge, Joel C. Rosenbaum, Anne E. Carlson 636-Pos Board B402 NEWLY SYNTHESIZED PHOSPHOLEMMAN PROTEIN SORTS THROUGH NUCLEAR ENVELOPE PUNCTA ALIGNED WITH T-TUBULES IN CARDIO MYOCYTES. Jin Guo, Steven E. Cala, Zhenhui Chen 637-Pos Board B403 WHAT MECHANISTIC INFORMATION IS CONTAINED IN SOLID-SUPPORT ED MEMBRANE ELECTROPHYSIOLOGY MEASUREMENTS OF AVERAGE TRANSPORTER CURRENTS? A BAYESIAN ANALYSIS. August George, Daniel M. Zuckerman 638-Pos Board B404 STRUCTURAL AND FUNCTIONAL DIVERSITY IN VERTEBRATE PRESTIN (SLC26A5) ORTHOLOGS. Patrick R. Haller , Navid Bavi, Eduardo Perozo 639-Pos Board B405 ACTIVATION MECHANISM OF THE CARDIAC CALCIUM PUMP BY A SMALL-MOLECULE ALLOSTERIC MODULATOR. Jaroslava Seflova , Carlos Cruz Cortes, Guadalupe Guerrero-Serna, Seth L. Robia, L. Michel Espinoza-Fonseca 640-Pos Board B406 LOCKED IN PLACE: DECIPHERING THE CONFORMATIONAL IMPAIR MENT CAUSED BY TUMOR-ACQUIRED SOMATIC MUTATION Q393K IN ABCG2. Ali Rasouli , Tomoka Gose, Sepehr Dehghani-Ghahnaviyeh, Po-Chao Wen, Yao Wang, John Lynch, Yu Fukuda, Talha Shafi, Robert C. Ford, John D. Schuetz, Emad Tajkhorshid

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