BPS2024 Full Program & Abstracts

716-Pos Board B482 NON-OPTIMAL GROWTH PHYSIOLOGY PROMOTES BACTERIAL SURVIVAL IN TIME-VARYING ANTIBIOTIC STRESS. Josiah Kratz , Shiladitya Banerjee 717-Pos Board B483 COMPARING SPATIAL BIOPHYSICAL SIMULATIONS ACROSS SCALES AND METHODS. Karthik R. Vegesna , Saurabh S. Mogre, Jessica Yu, Blair Lyons, . Allen Institute for Cell Science, Aadarsh Raghunathan, Eran Agmon, Matthew Akamatsu, Graham T. Johnson 718-Pos Board B484 BIOPHYSICAL PRINCIPLES PREDICT FITNESS OF SARS-COV-2 VARI ANTS. Dianzhuo Wang , Marian Huot, Vaibhav Mohanty, Eugene Shakh novich 719-Pos Board B485 MODELING ORGANELLAR AND SUBCELLULAR MEMBRANE BENDING USING MEM3DG. Christopher T. Lee , Padmini Rangamani 720-Pos Board B486 IMPROVING DIFFICULT INFERENCE TASKS AND LIKELIHOOD EVALUA TIONS WITH NEURAL NETWORKS. Pedro Pessoa , Steve Pressé 721-Pos Board B487 STRUCTURE OF THE HIV IMMATURE LATTICE ALLOWS FOR ESSENTIAL LATTICE REMODELING WITHIN BUDDED VIRIONS. Sikao Guo , Ipsita Saha, Saveez Saffarian, Margaret E. Johnson 722-Pos Board B488 THE ACTOMYOSIN CORTEX REQUIRES FRICTION TO AVOID CONSTRIC TIONAL SHAPE INSTABILITY. Hongkang Zhu , Roberto Alonso-Matilla, Ben O'Shaughnessy 723-Pos Board B489 Travel Award Winner MODELING SHEAR BANDING LIPID MONOLAYER COLLAPSE WITH FINITE ELEMENT ANALYSIS. Anna D. Gaffney , Dongxu Liu, Angelo R. Carotenu to, Kathleen D. Cao, Luca Deseri, Ka Yee C. Lee, Luka Pocivavsek, Nhung Board B490 MEMBRANELESS ORGANIZATION IN A MOLECULARLY CROWDED ENVIRONMENT: INTERPLAY BETWEEN ASSOCIATIVE AND SEGREGATIVE LLPS SYSTEMS. Caroline M. Love , Chang Chen, Christopher F. Carnahan, Siddharth Deshpande, Atul N. Parikh 725-Pos Board B491 ILLUMINATING DYNAMIC CELLULAR STATES IN HIPSCS THROUGH EN DOGENOUS GENE TAGGING. Brock Roberts In Vitro Cryo-EM: Methods and Applications (Boards B492 - B510) 726-Pos Board B492 A RAPID AUTOMATED SYSTEM FOR NEGATIVE STAINING EM. Vu Nguyen , Arun Kumar Somavarapu, Ruchi Gautam Sharma, Debabrata Dutta, Roger Craig, Raul Padron 727-Pos Board B493 STREAMLINED PRODUCTION OF GRAPHENE-SUPPORTED GRIDS EN HANCES CRYO-EM SAMPLE PREPARATION. Rachel Smith, Xing Meng, Ishara Ratnayake, Gongpu Zhao 728-Pos Board B494 Travel Award Winner DEEPMAINMAST AND CRYOREAD: PROTEIN AND DNA/RNA STRUCTURE MODELING FOR CRYO-EM USING DEEP LEARNING. Genki Terashi , Xiao Wang, Tsukasa Nakamura, Daisuke Kihara 729-Pos Board B495 ANALYZING THE STATE OF CRYOEM STRUCTURAL BIOLOGY USING HIER ARCHICAL ATOMIC RESOLUTION PERCEPTION. Korak Kumar Ray, Colin D. Kinz-Thompson Nguyen 724-Pos

730-Pos Travel Award Winner DAQ-SCORE DATABASE AND DAQ-REFINE: DEEP-LEARNING BASED QUALITY ESTIMATION AND REFINEMENT OF CRYO-EM DERIVED PRO TEIN MODELS. Tsukasa Nakamura , Xiao Wang, Genki Terashi, Daisuke Kihara 731-Pos Board B497 PREDICTING PROBLEMS CAUSED BY THE AIR-WATER INTERFACE IN CRYO-ELECTRON MICROSCOPY: INSIGHTS FROM MOLECULAR DYNAM ICS SIMULATIONS. Abhilash Sahoo , Sonya M. Hanson 732-Pos Board B498 MONTE CARLO SIMULATION OF ELECTRON INTERACTIONS IN AN MEV STEM FOR THICK FROZEN BIOLOGICAL SAMPLE IMAGING. Liguo Wang , Xi Yang 733-Pos Board B499 PROBING HETEROGENEITY OF TRPV1: A COMPARISON OF STATE-OF THE-ART METHODS IN CRYO-EM. Miro A. Astore , Robert Blackwell, Pilar Cossio, Sonya M. Hanson 734-Pos Board B500 WHERE CRYO-ELECTRON AND COMPUTATIONAL MICROSCOPY CON VERGE: THE STORY OF THE ELUSIVE FLIPBACK CONFORMATION OF PRO TEIN KINASE A AND ITS CRITICAL ROLE IN PHOSPHODIESTERASE CYCLIC AMP CHANNELING. Sophia P. Hirakis , Varun Venkatakrishnan, Zacharias Faidon Brotzakis, Jian Wu, Gary Huber, Susan S. Taylor, Ganesh S. Anand 735-Pos Board B501 UNDERSTANDING CYSTATHIONINE BETA SYNTHASE MECHANISM OF ACTION AND INTERACTION WITH SUBSTRATES, PRODUCT, INHIBITORS, ALLOSTERIC MODULATORS. Sainath Polepalli , Anupam Roy, Ishika Pra manick, Amit Singh, Somnath Dutta 736-Pos Board B502 SEM IMAGE OF DNA STAINED BY PROTEIN AND POLYMER WITHOUT METALS. Chanyoung Noh 737-Pos Board B503 DEVELOPING A STANDARDIZED PROTOCOL FOR DETERMINING FIBRIN FIBER DIAMETER FROM ANALYSIS OF SCANNING ELECTRON MICROSCO PY IMAGES. Can Cai , Marlien Pieters, Zelda de Lange, Stephen R. Baker, Albe Swanepoel, Rustem I. Litvinov, Chandrasekaran Nagaswami, John W. Weisel, Martin Guthold 738-Pos Board B504 CRYO-EM STRUCTURE OF A 55 KDA NUCLEOPLASMIN PROTEIN. Nikhil Bharambe , Ketul Saharan, Dileep Vasudevan, Sandip Basak 739-Pos Board B505 SPOT-RASTR - A CRYO-EM SPECIMEN PREPARATION TECHNIQUE THAT OVERCOMES PROBLEMS WITH PREFERRED ORIENTATION AND THE AIR/ WATER INTERFACE. Behrouz Ghazi Esfahani , Peter S. Randolph, Ruizhi Peng, Elizabeth Stroupe, Tim Grant, Scott M. Stagg 740-Pos Board B506 COMPUTATIONAL ANALYSIS OF LIGANDS ENABLES NEAR-ATOMIC CRYO EM STRUCTURE-BASED DRUG DESIGN (CRYO-EM SBDD). Qiu-Xing Jiang , Ceng Gao, Gaya P. Yadav, Zhuoya Wang, Shuai Yang 741-Pos Board B507 A HIGH RESOLUTION LOOK AT FRESH HUMAN BRAIN VITRIFIED DI RECTLY FROM AUTOPSY USING CRYO-ELECTRON TOMOGRAPHY WITH CRYO-PLASMA FOCUSED ION BEAM MILLING. Benjamin C. Creekmore , Kathryn Kixmoeller, Ben E. Black, Edward B. Lee, Yi-Wei Chang 742-Pos Board B508 CRYO-EM STRUCTURES OF NANODISC RECONSTITUTED PROKARYOTIC LIGAND-GATED ION CHANNEL GLIC IN VARIOUS CONFORMATIONS REVEAL STATE-DEPENDENT PROTEIN-LIPID INTERACTIONS AND GATING MECHANISM. Nikhil Bharambe, Zhuowen Li, David Seiferth, Asha Manik koth Balakrishna, Philip C. Biggin, Sandip Basak Board B496

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