BPS2024 Full Program & Abstracts

Board S67 CONTROLLED BY DISORDER: PROBING HOW THE PROTEIN SRSF1 IS ALTERED BY MODIFICATION OF ITS UNSTRUCTURED C-TERMINUS. Talia Fargason (1992 Pos / B141) Board S68 COUPLED TR-FRET AND MOLECULAR DYNAMICS PREDICT NOVEL TROPOMYOSIN INTERACTIONS AND DISEASE MECHANISMS IN C TERMINAL TAIL OF CARDIAC TROPONIN T. Garrett Crosby (2249 Pos / B398) Board S69 DECIPHERING THE MOLECULAR LANGUAGE OF FUS PHASE SEPARATION. Shuo-Lin Weng (391 Pos / B157) Board S70 DIRECT PREDICTION OF INTRINSICALLY DISORDERED PROTEIN CONFOR MATIONAL PROPERTIES FROM SEQUENCE. Jeffrey M. Lotthammer (278 Pos / B44) Board S71 ELUCIDATING PRINCIPLES GOVERNING THE MULTICOMPONENT PHASE SEPARATION OF DISORDERED PROTEINS. Kandarp A. Sojitra (2758 Pos / B150) Board S72 MEMBRANE-ASSISTED AGGREGATION OF AΒ40. Fidha Nazreen Kunnath Muhammedkutty (1185 Pos / B138) Board S73 NACL MEDIATES THE PHASE SEPARATION OF THE HNRNPA1 LOW-COM PLEXITY DOMAIN BY NEUTRALIZING CHARGES AND BRIDGING INTER MOLECULAR INTERACTION NETWORKS. Matthew MacAinsh (2761 Pos / B153) Board S74 POLYPHENOL BASED MODULATION OF STRUCTURE AND TOXICITY OF HUNTINGTIN PROTEIN AGGREGATES. Greeshama Jain (2728 Pos / B120) Board S75 REVERSING ABERRANT PHASE TRANSITIONS OF ALS-LINKED DISEASE PROTEIN FUS WITH RNA. Jenny L. Carey (1180 Pos / B133) Macromolecular Machines and Assemblies (Boards S76 – S85) Board S76 AUGMENTING THE BACTERIAL RIBOSOME ASSEMBLY STRUCTUROME USING ANTI-SENSE OLIGONUCLEOTIDE ANALOGS. Kai Sheng (2002 Pos / B151) Board S77 DIRECT STACKING OF PERIPHERAL DUPLEXES SIGNIFICANTLY STABILIZES RNA TRIPLE HELICES. Mary N. Mwangi (2023 Pos / B172) Board S78 DIRECTED EVOLUTION OF A BIFUNCTIONAL PC2 DEHYDROGENASE/SHC FERROCHELATASE. Yashika Garg (1072 Pos / B25) Board S80 HOW DO CHAPERONINS RECOGNIZE SUBSTRATE PROTEINS? Junlang Liu (1107 Pos / B60)

Board S81 MOLECULAR INSIGHT INTO THE MAMMALIAN SLFN14 RIBONUCLEASE. Justin M. Van Riper (1945 Pos / B94) Board S82 MOLECULAR MECHANISMS AND ENERGETICS UNDERLYING THE DYNEIN PRIMING STROKE. Mert Gölcük (674 Pos / B440) Board S83 SOLID-STATE NMR REVEALS SIGNALING-RELATED CHANGES IN FUNC TIONAL CHEMOTAXIS RECEPTOR COMPLEXES. Jessica Allen (538 Pos / B304) Board S84 STRUCTURAL BASIS OF CLOSTRIDIUM PERFRINGENS ENTEROTOXIN ACTIVATION AND OLIGOMERIZATION BY TRYPSIN. Chinemerem P. Ogbu (1908 Pos / B57) Board S85 STRUCTURE-GUIDED MUTATIONS OF THE UBIQUITIN CONJUGATING ENZYME UBCH5B IN ORDER TO STUDY A DOWNSTREAM COMPLEX. Maleesha D. Marakkala Manage (1906 Pos / B55) Mechanobiology (Boards S86 – S91) Board S86 FORCE-INDUCED SALT BRIDGE FORMATION ENHANCES HP1 HOMODI MER INTERACTION, IMPLYING AUGMENTED CHROMATIN CROSSLINK ING AND PHASE SEPARATION. Shingo Tsukamoto (2041 Pos / B190) Board S87 OPEN-SOURCE ALGORITHM FOR HIGH-THROUGHPUT, NON-CONTACT ELASTICITY MEASUREMENTS OF IPSC-DERIVED CARDIOMYOCYTES. Adithan Kandasamy (2255 Pos / B404) Board S88 PHOTOSWITCHABLE LIPID DYNAMICS IN PHASE-SEPARATED MEM BRANES. Tsu-Wang Sun (2877 Pos / B269) Board S89 PIEZO1-HALOTAG HISPC LINES: A NEW TOOL TO ASSAY PIEZO1 LOCAL IZATION AND ACTIVITY FROM SINGLE CELLS TO TISSUE ORGANOIDS. Gabriella A. Bertaccini (1347 Pos / B300) Board S90 QUANTIFICATION OF COLLECTIVE PODOSOME WAVE DYNAMICS USING SPATIO-TEMPORAL IMAGE CORRELATION SPECTROSCOPY (STICS). Rodrigo A. Migueles-Ramirez (3022 Pos / B414) Board S91 SELF-ORGANIZATION OF OVARIAN CANCER ORGANOIDS REVEALED BY 3D IMAGE SEGMENTATION AND PHASE-FIELD MODEL. Toshikaze Chiba (2276 Pos / B425)

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