BPS2024 Full Program & Abstracts

Graduate Student Breakfast 7:30 am - 8:30 am, Room 105AB

No Abstract 9:05 am OSCILLATIONS AND PHASE SEPARATIONS IN DNA REPAIR REGULATION.

Mathias Heltberg 854-SympSelect

M O N D A Y

This breakfast presents an opportunity for graduate student Annual Meeting attendees to meet and discuss the issues they face in their cur rent career stage. Limited to the first 100 attendees. Moderators Peying Fong, Kansas State University, USA Christian Jorgensen, Portsmouth University, United Kingdom Francisco Barrera, University of Tennessee, Knoxville, USA Speakers Jeffrey Schaub, Abbott Laboratories, USA Helene Hodak, Cell Press, USA Registration/Exhibitor Registration 7:30 am - 5:00 pm, Registration Bridge West Poster Viewing 8:00 am - 10:00 pm, Exhibit Hall AB Symposium Structural Mechanisms of GPCR Activation, Regulation, and Signaling 8:15 am - 10:15 am, Ballroom A Chair Jennifer Cash, University of California, Davis, USA No Abstract 8:15 am A NOVEL ALLOSTERIC MECHANISM OF INVERSE AGONISM DISCOVERED IN ORPHAN RECEPTOR GPR61. Joshua Lees 850-Symp 8:40 am STRUCTURAL MECHANISMS OF CLASS B GPCR ACTIVATION AND SIG NALING. Patrick M. Sexton 851-Symp 9:05 am STRUCTURAL BASIS OF ANTIBODY INHIBITION AND CHEMOKINE ACTIVATION OF THE HUMAN CC CHEMOKINE RECEPTOR 8. Matthieu Masureel 853-SympSelect 9:30 am MODULATION OF CLASS B GPCRS BY THEIR LIPID ENVIRONMENT. Kin Chao, Affiong Oqua, Alejandra Tomas, Sarah L. Rouse 852-Symp 9:50 am STRUCTURAL DYNAMICS IN RHOGEF SIGNALING INVESTIGATED USING MODEL CELL MEMBRANES. Sandeep Ravala, Sendi Adame-Garcia, Sheng Li, Chun-Liang Chen, Michael A. Cianfrocco, J. Silvio Gutkind, Jen nifer Cash , John J. Tesmer Symposium The Fluid Versus Gel Nature of the Genome 8:15 am - 10:15 am, Ballroom B Chair Laura Finzi, Emory University, USA No Abstract 8:15 am DECIPHERING THE PHYSICAL AND BIOLOGICAL DRIVERS IMPACTING THE ANOMALOUS MOTION OF CHROMOSOMES IN LIVING CELLS. Andrew Spakowitz No Abstract 8:40 am CHROMOSOME SEGREGATION IN A CROWDED SPACE. Christine Jacobs Wagner

9:30 am “IF YOU’RE NOT IN, YOU’RE OUT”: CONFORMATIONAL ENTROPY OF INTRINSICALLY DISORDERED PROTEINS BARS INTRUDERS FROM BIO MOLECULAR CONDENSATES. Ned S. Wingreen , Yaojun Zhang, Vladimir Grigorev 855-Symp 9:50 am MACROMOLECULAR CROWDERS: INFLUENCERS OF DNA STRUCTURE AND TOPOLOGY. Laura Finzi Platform Optical Microscopy and Superresolution Imaging II 8:15 am - 10:15 am, Room 103AB Co-Chairs Anna-Karin Gustavsson, Rice University, USA Rozhin Penjweini, NHLBI, NIH, USA 856-Plat 8:15 am LOW DOSE TAXOL DAMAGES MITOCHONDRIA. Rozhin Penjweini , Katie A. Link, Shureed Qazi, Adam Zuchowski, Alexandra Vasta, Dan L. Sackett, Jay R. Knutson 857-Plat 8:30 am INTEGRATING MICROFLUIDICS AND A TILTED SINGLE-OBJECTIVE LIGHT SHEET FOR WHOLE-CELL MULTI-TARGET 3D SINGLE-MOLECULE SUPER RESOLUTION IMAGING. Gabriella Gagliano, Nahima Saliba, Anna-Karin Gustavsson 858-Plat 8:45 am SINGLE-MOLECULE LABELING ACHIEVES ENHANCED NANOSCALE IMAG ING OF F-ACTIN IN FRAGILE MEMBRANE STRUCTURES OF DENDRITIC CELLS. Hirushi T. Gunasekara Kalu Arachchige , Thilini Perera, Badeia Saed, Ying Hu 859-Plat 9:00 am COMPARING ABSOLUTE NUMBERS OF GLUA1 AND GLUA2 IN HIP POCAMPAL NEURONS THROUGH QPAINT. Gloria W. Lau , Max Winga, Timothy James Tan, Ruipeng Lei, Hee Jung Chung, Nicholas C. Wu, Paul 9:15 am VISUALIZING PRIMARY CILIA WITH 1 NM LOCALIZATION PRECISION VIA EXPANSION SINGLE MOLECULE LOCALIZATION MICROSCOPY. Jimmy Ching-Cheng Hsu , Ting-Jui Chang, Ariel Yurusova, Tony Yang 861-Plat 9:30 am Travel Award Winner DISTINCT COMPLEXES CONTAINING THE CYTOSOLIC TYPE III SECRETION SYSTEM ATPASE SCTN RESOLVED BY 3D SINGLE-MOLECULE TRACKING IN LIVE YERSINIA ENTEROCOLITICA . Olivia I.C. de Cuba , Joshua R. Prindle, Caroline F. Tyndall, Andreas Gahlmann 862-Plat 9:45 am A PHYSICALLY ACCURATE FRAMEWORK FOR STRUCTURED ILLUMINA TION MICROSCOPY IN THE SPATIAL DOMAIN. Ayush Saurabh , Peter Brown, Shep Bryan IV, Rory Kruithoff, Zachary Fox, Douglas P. Shepherd, Steve Pressé 863-FlashTalk 10:00 am SINGLE-MOLECULE ORIENTATION AND POSITION MEASUREMENT AS SISTED BY DEEP LEARNING AND POINT SPREAD FUNCTION ENGINEER ING. Pierre Jouchet , Anish R. Roy, William E. Moerner R. Selvin 860-Plat

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