BPS2024 Full Program & Abstracts

864-FlashTalk 10:05 am EXPLOTING THE DETECTOR DISTANCE INFORMATION IN IMAGE SCAN NING MICROSCOPY BY SPLIT-ISM. Elisabetta Di Franco , Paolo Bianchini, Giuseppe Vicidomini, Alberto Diaspro, Giulia Tedeschi, Lorenzo Scipioni, Enrico Gratton, Michelle A. Digman, Luca Lanzanò 865-FlashTalk 10:10 am A STATISTICAL RESOLUTION MEASURE OF FLUORESCENCE MICROSCOPE WITH FINITE PHOTONS. Yilun Li Platform Protein-Lipid Interactions 8:15 am - 10:15 am, Room 113AB Co-Chairs Navid Bavi, University of California, Los Angeles, USA Xiaobing Chen, University of Texas at Austin, USA 866-Plat 8:15 am STRUCTURAL ENSEMBLE OF PEPTIDE-INDUCED MEMBRANE PORATION BY MAGAININ PEPTIDES. Bing Zan 867-Plat 8:30 am STRUCTURAL BASIS OF MCR-1-MEDIATED POLYMYXIN RESISTANCE. Al len P. Zinkle , Rie Nygaard, Carmen Herrera, Satchal K. Erramilli, Khuram U. Ashraf, Mariana Batista, Melanie Odenkirk, Guozhi Zhang, Brian Kloss, Michael T. Marty, Anthony A. Kossiakoff, Phillip J. Stansfeld, Stephen Trent, Filippo Mancia 868-Plat 8:45 am BINDING-INDUCED LIPID DOMAINS: PEPTIDE-MEMBRANE INTERAC TIONS WITH PIP 2 AND PS. Xiaobing Chen , Ziareena Al-Mualem, Azam Shafieenezhad, Eric N. Senning, Carlos R. Baiz 869-Plat 9:00 am PROTECTIVE EFFECT OF MELATONIN AGAINST amYLOID-BETA-INDUCED DAMAGE IN MODEL LIPID MEMBRANES. Nanqin Mei , Carina T. Filice, Julia I. Lumini, Jingwen Liang, Danielle M. McRae, Weilin Wei, Ayumi Sumino, Takeshi Fukuma, Zoya Leonenko 870-Plat 9:15 am EFFECTS OF LIPID COMPOSITION ON THE CURVATURE SENSING OF HUNTINGTIN'S N17 DOMAIN. Neha Nanajkar , Abhilash Sahoo, Silvina 9:30 am LIPIDS INFLUENCE THE OLIGOMERIC ORGANIZATION OF VDAC1. Elodie Lafargue, Jean-Pierre Duneau, Nicolas Buzhinsky, James N. Sturgis, Igna cio I. Casuso, Lucie Bergdoll 872-Plat 9:45 am THE KIRBAC1.1 INWARD-RECTIFIER K + CHANNEL IS OPENED COOPERA TIVELY BY ANIONIC LIPIDS. Benjamin J. Wylie , Collin G. Borcik, Reza amani, Evan J. van Aalst, Maryam Yekefallah, Isaac R. Eason, Carver Rasberry, Roy A.M. van Beekvelld, Markus Weingarth, Chad M. Rienstra, 10:00 am EXPLORING LIPID BINDING SITES ON TRPVS USING COARSE-GRAINED MOLECULAR DYNAMICS SIMULATIONS. Mario López-Martín , Eric Catalina-Hernandez, Alex Peralvarez-Marin, Mohsen Habibnia 874-FlashTalk 10:05 am STRUCTURAL IMPLICATIONS OF LIPID PROTEIN INTERACTIONS IN PRES TIN MEDIATED ELECTROMOTILITY. Navid Bavi , Patrick R. Haller, Eduardo Perozo Matysiak 871-Plat Eefjan Breukink 873-FlashTalk

875-FlashTalk Travel Award Winner THE DRUG-STIMULATED ATPASE ACTIVITY OF P-GLYCOPROTEIN: THE INFLUENCE OF LIPID ENVIRONMENT. Nghi Tran , Anthony A. Bui, Valeria Jaramillo-Martinez, Joachim Weber, Qinghai Zhang, Ina Urbatsch Platform Protein Structure and Conformation II 8:15 am - 10:15 am, Room 201AB Co-Chairs Reginald McNulty, University of California, Irvine, USA Shawn Rumrill, Rutgers University, USA 876-Plat 8:15 am CRYSTAL STRUCTURES OF AN HIV-1 REVERSE TRANSCRIPTASE SECOND STRAND INITIATION COMPLEX WITH AND WITHOUT NON-NUCLEOSIDE INHIBITORS MAY EXPLAIN SLOW NUCLEOTIDE INCORPORATION AND HIGH SENSITIVITY TO INHIBITION. Shawn Rumrill , Francesc X. Ruiz, Eddy Arnold 877-Plat 8:30 am THE ROLE OF HEPARIN IN SPIKE SARS-COV-2 INFECTION: FROM A MOD EL FOR HEPARAN SULFATES TO A STARTING STRUCTURE FOR ANTIVI RALS. Giulia Paiardi , Maria Milanesi, Matheus Ferraz, Liv Zimmermann, Chiara Urbinati, Pasqua Oreste, Francesca Caccuri, Petr Chlanda, Marco Rusnati, Rebecca C. Wade 878-Plat 8:45 am FUSION PEPTIDE DYNAMICS DURING RECEPTOR-INDUCED CONFORMA TIONAL CHANGES IN THE HIV-1 ENVELOPE. Bhishem Thakur , Katarzyna Janowska, Priyamvada Acharya 879-Plat 9:00 am Travel Award Winner FLIPPED OVER U: STRUCTURAL BASIS FOR DSRNA CLEAVAGE BY THE SARS-COV-2 ENDORIBONUCLEASE. Meredith N. Frazier , Monica Pillon, Lucas Dillard, Juno Krahn, Isha Wilson, Jason Williams, Lalith Perera, Kevin John Butay, Leesa Deterding, Mario J. Borgnia, Robin Stanley 880 -Plat 9:15 am Travel Award Winner CONFORMATIONAL DYNAMICS OF HENIPAVIRUS FUSION PROTEINS. Aaron J. May , Priyanka Devkota, Xiao Huang, Salam Sammour, Katar zyna Janowska, Kijun Song, Priyamvada Acharya 881-Plat 9:30 am Travel Award Winner INVESTIGATING THE STRUCTURE AND FUNCTION OF THE NOVEL CAULOBACTER CRESCENTUS TRANSCRIPTION ACTIVATOR, DRID. Emily Cannistraci , Maria Schumacher 882 -Plat 9:45 am Travel Award Winner ELUCIDATING THE MECHANISM OF NLRP3 INFLAMMASOME INTER ACTION WITH MITOCHONDRIAL DNA. Angela Cabral, Julia E. Cabral, Reginald McNulty 883 -FlashTalk 10:00 am CHARTING THE CONFORMATIONAL DYNAMICS OF HUMAN FATTY ACID SYNTHASE USING CRYO-EM. Naimul Hasan , Alexander Keszei, Moham mad Mazhab-Jafari 884 -FlashTalk 10:05 am Travel Award Winner STRUCTURAL INSIGHTS INTO CROSS-REACTIVE ANTIBODIES RECOGNIZ ING THE N-TERMINAL AND RECEPTOR BINDING DOMAINS OF THE SARS COV-2 SPIKE GLYCOPROTEIN. Adonis Rubio , Morgan Abernathy, Yu Erica Lee, Teresia Chen, Christopher O. Barnes 885-FlashTalk 10:10 am Travel Award Winner MOLECULAR MECHANISM OF HOLLIDAY JUNCTION BRANCH MIGRA TION. Anthony Rish , Zhangfei Shen, Zhenhang Chen, Tianmin Fu 10:10 am

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