BPS2024 Full Program & Abstracts

Platform Intracellular Organelles and Bioenergetics 8:15 am - 10:15 am, Room 204C

Career Development Center Workshop Demystifying the Academic Job Search I:

M O N D A Y

Understanding the Search 9:00 am - 10:00 am, Room 108B

Co-Chairs Tatiana Rostovtseva, NIH, USA Lei Shen, Yale University, USA 906-Plat 8:15 am

What goes on inside search committees; the “black box” of the academic job search process? How are they constituted, what are their processes, and what do they look for when assessing applicants? Answers to these and other questions presented by Andrew Green, PhD a veteran of the academic job search and numerous search committees.

VISUALIZING THE DYNAMICS OF CELL DIVISION THROUGH 3D MODELS CONSTRUCTED FROM ELECTRON MICROSCOPY. Jin Kousaka , Atsuko H. Iwane, Yuichi Togashi 907-Plat 8:30 am Travel Award Winner SELF-ORGANIZATION OF GLYCOLYTIC ACTIVITY INTO CORTICAL WAVES FUELS CELL MIGRATION AND CANCER PROGRESSION. Huiwang D. Zhan , Dhiman S. Pal, Jane Borleis, Chris Janetopoulos, Bear Huang, Peter N. Devreotes 908 -Plat 8:45 am MITOCHONDRIAL ROS SIGNALING DURING SYNAPTIC POTENTIATION. Irina Stavrovskaya, Bethany Kristi Morin, Pablo M. Peixoto 909 -Plat 9:00 am CHANNEL CONFORMATIONAL PLASTICITY OF MITOCHONDRIAL VDAC2 CONTROLS ITS INTERACTION KINETICS WITH CYTOSOLIC PROTEINS. Wil liam M. Rosencrans, Tsyr-Yan Yu, Motahareh Ghahari Larimi, Radhakrish nan Mahalakshmi, Sergey M. Bezrukov, Tatiana K.R. Rostovtseva 910-Plat 9:15 am CRYO-ELECTRON MICROSCOPY STUDIES REVEAL THE INACTIVATION MECHANISM OF ATP SYNTHASE LEAK CHANNEL AND ITS CONTRIBU TION TO MITOCHONDRIAL PERMEABILITY TRANSITION. amrendra Kumar , Juliana da Fonseca Rezende e Mello, Yangyu Wu, Daniel Morris, Nelli Mnatsakanyan 911-Plat 9:30 am SPATIO-TEMPORAL HETEROGENEITY OF MITOCHONDRIA DURING DIF FERENTIATION OF HIPSC-DERIVED NEURONS. Karin B. Busch , Jimmy Villalta Villalobus 912-Plat 9:45 am A NOVEL MITOCHONDRIAL TARGET AS A THERAPEUTIC APPROACH TO BIPOLAR DISORDER. Lei Shen , Jonghun Kim, In-Hyun Park, Hilary Blum berg, Elizabeth A. Jonas 913-FlashTalk 10:00 am ENERGY TRANSFER PATHWAYS IN IN THE PHOTOSYSTEM SUPERCOM PLEXES OF FRAGILARIOPSIS SP AND P. TRICORNUTUM . Constantinos A. Varotsis , Charalampos Andreou, Charalampos Tselios, Panagiotis Loukakos, Nikos Kountourakis, Giorgos Gouridis 914-FlashTalk 10:05 am SELF-SUPERVISED DEEP LEARNING UNCOVERS THE SEMANTIC LAND SCAPE OF DRUG-INDUCED LATENT MITOCHONDRIAL PHENOTYPES. Zichen Wang 915-FlashTalk 10:10 am FMRP GRANULES DRIVE MITOCHONDRIAL FISSION VIA LOCAL TRANSLA TION IN NEURONS. Adam Fenton , Ruchao Peng, Charles Bond, Siewert Hugelier, Melike Lakadamyali, Yi-Wei Chang, Erika Holzbaur, Thomas Jongens CID Committee Meeting 8:30 am - 10:30 am, Room 106AB

Exhibitor Presentation Sophion Bioscience A/S 9:30 am - 11:00 am, Room 103C

Recent Advances in Automated Patch Clamp Assays Using Primary and iPSC-Derived Cells; and Virtual Screening for Modulators of KCa, Nav1.7, and GABA-A Channels: Does it Work? Successful ion channel drug discovery requires the integration of multiple technologies and workflows. Sophion Bioscience is a leader in automated patch clamp technology, providing low, medium and high throughput patch clamp systems to the drug discovery industry and aca demia. The QPatch and Qube are fully automated patch clamp systems, executing simultaneous 16, 48 or 384 parallel patch clamp recordings in conjunction with computer controlled liquid handling and on-board cell handling. The QPatch Compact is a manual patch clamp system that can execute individual or simultaneous 8 patch clamp recordings. Sophion provides customers with robust, ion channel and electrophysiological workflows for the drug development of ion channel targets. During this workshop, speakers will provide insight into the use of these systems with primary and iPSC cells, and the use of virtual screening in comparison to automated patch clamp in the drug discovery process. Speakers Daniel Sauter, Scientific Sales Manager, Sophion Bioscience A/S Heike Wulff, Professor, University of California, Davis Meet the Editors Biophysical Journal , Biophysical Reports , and The Biophysicist 10:00 am - 11:15 am, Grand Hall Take this opportunity to meet editors of all three of the Society's pres tigious journals! The Editors-in Chief, members of the Editorial Boards, and BPS staff will be available to answer your questions about what areas of research the journals cover, how to give your paper the best chance of being accepted, the submission process, special issues, and anything else related to BPS journals. Exhibits 10:00 am - 5:00 pm, Exhibit Hall AB Coffee Break

10:15 am - 11:00 am, Exhibit Hall AB New Member Welcome Coffee 10:15 am - 11:15 am, Room 105AB

Calling all new BPS members! Come and mingle with BPS Staff, Society Council, and program members as you learn about the Society’s activi ties. Current members are welcome to attend and meet with new members.

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