BPS2026 Program Book

Protein Structure and Conformation II (Boards B1 - B17)

839-Pos Board B13 DETECTION OF PROTEIN-PROTEIN RECOGNITION SITES USING PERTUR BATION RESPONSE SCANNING. Diksha Parwana , Ivet Bahar 840-Pos Board B14 SOLUTION- AND SOLID-STATE NMR OF BIOMIMETIC AND ENZYMATIC SYSTEMS. Bethany G. Caulkins 841-Pos Board B15 INTERFAMILY CROSSTALK BETWEEN ERK2, RSK2, AND MTORC2 ACROSS FOUR KINASE FAMILIES. Hoang P.M. Nguyen , Evan K. Kobori, Jian Wu, Roland Dunbrack, Mariusz Matyszewski, Rodeon Malinovski, Katherine Chen, Mark A. Herzik, Susan S. Taylor 842-Pos Board B16 Travel Award Winner STRUCTURAL AND MECHANISTIC INSIGHTS INTO EFFECTOR ENGAGE MENT AND TRANSLOCATION BY THE LEGIONELLA DOT/ICM SECRETION SYSTEM. Radha P. Somarathne , Riti Shrestha, Mishghan Zehra, Cole Brodeur, Wing-Cheung Lai, Clarissa L. Durie 843-Pos Board B17 HIGH-THROUGHPUT FABRICATION OF GRAPHENE-SUPPORTED GRIDS FOR CRYO-EM SAMPLE PREPARATION. Gongpu Zhao , Xing Meng Protein Assemblies (Boards B18 - B44) 844-Pos Board B18 EXPLORING ESCRT III POLYMERIZATION SEQUENCE THROUGH 3D ANI MATION . Margot Riggi , Javier Espadas, Joshua Tran, Aurelien Roux 845-Pos Board B19 MOLECULAR MODELING AND MOLECULAR DYNAMICS SIMULATION OF A PACKED AND INTACT BACTERIAL MICROCOMPARTMENT. Saad Raza, Neetu S. Yadav, Alexander Jussupow, Cheryl Kerfeld, Michael Feig, Josh V. Vermaas 846-Pos Board B20 VISUAL EXOPROTEOMICS OF CLOSTRIDIUM THERMOCELLUM ENGAGED IN BIOMASS DEGRADATION. Matthew P. Agdanowski , Matthew J. Kensil, Robert Gunsalus, Tracy al-Set, Ethan Humm, Rachel Loo, Joseph Loo, Jose A. Rodriguez 847-Pos Board B21 Travel Award Winner REVEALING THE COMPLEX ARCHITECTURE OF AN ARCHAEAL CELL END BY IN SITU CRYOET AND FIB MILLING. Angela Agnew , Hui Wang, Ethan Humm, Nagaa Joseph, Hong Zhou, Robert Gunsalus 848-Pos Board B22 CRYO-EM INVESTIGATIONS OF THE STRUCTURE AND MECHANISM OF THE R-BODY, A PH-SENSITIVE PROTEIN MACHINE. Natalie Stone , Guang yang Cai, Justin M. Kollman 849-Pos Board B23 DISSECTING THE MOLECULAR MACHINERY OF CRYPTOSPORIDIUM PARVUM FERTILIZATION USING CRYO-ET. Fenglin Li 850-Pos Board B24 MECHANISMS AND KINETICS OF HIV-1 CAPSID SELF-ASSEMBLY FROM A MOMENT OF INERTIA-BASED COARSE-GRAINING METHOD. Akarsh Kumar Dash , Dustin Hoang, Elizabeth M.Y. Lee, Alvin Yu 851-Pos Board B25 HIV MATURATION FROM MOLECULAR SIMULATIONS OF A COMPLETE VIRION. Sinai Lee , Ethan Wang, Alvin Yu 852-Pos Board B26 MECHANISTIC INSIGHTS INTO LENACAPAVIR-INDUCED OFF-PATHWAY HIV CAPSID ASSEMBLY. Manish Gupta , Curt Waltmann, Nadine Renner, Yihang Wang, Leo James, David Jacques, Till Böcking, Gregory A. Voth

M O N D A Y

827-Pos Board B1 STRUCTURAL AND FUNCTIONAL ANALYSIS OF NSP15-T112I FROM SARS COV-2 USING X-RAY CRYSTALLOGRAPHY. Nirmali Sandunika Siriward hana Kulathunga Kankanamalage , Manashi Sonowal, Petra Fromme 828-Pos Board B2 Travel Award Winner AN EYE LENS PROTEIN FORMS A TRANSPARENT HYDROGEL VIA TRAN SIENT INTERMOLECULAR INTERACTIONS. Jaewon Suk , Ravi S. Palani, Hao-wei Shih, Marc Sprague-Piercy, Robert G. Griffin, Jin K. Montclare, Rachel W. Martin 829-Pos Board B3 INVESTIGATING MOLECULAR CROWDING EFFECTS ON THE MULTI DOMAIN ESCHERICHIA COLI PROLYL-TRNA SYNTHETASE USING ATOMIC FORCE MICROSCOPY. Oscar R. Vlcek , Aaron Botsch, Dylan R. Weaver, Sanchita Hati 830-Pos Board B4 BRIDGING THE CONFORMATIONAL LANDSCAPES OF THE ACTIVE AND INACTIVE FORMS OF ARF6 USING HIGH PRESSURE. Noam Hantman , Tejaswi Naidu Koduru, Scott A. McCallum, Catherine A. Royer 831-Pos Board B5 PHYSIOLOGICAL TEMPERATURE DRIVES TRPM4 LIGAND RECOGNITION AND GATING. Jinhong Hu 832-Pos Board B6 STRUCTURAL AND MECHANISTIC INSIGHTS INTO RNA UNWINDING BY THE HUMAN SUV3 HELICASE IN MITOCHONDRIAL RNA DECAY. Malay Patra, Woei-Chyn Chu, Hanna S. Yuan 833-Pos Board B7 OPTIMIZING CRYO-EM SAMPLE PREPARATION FOR HCMV GB-ANTIBODY COMPLEXES. Mohammad Karimian Shamsabadi , Yu-Hsin Wan, Nicholas Aldridge, Andrew McGuire, Ekaterina Heldwein 834-Pos Board B8 MAPPING THE STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CRYPTIC SEQUENCE VARIATION IN PATHOGENIC NEW WORLD HEMOR RHAGIC FEVER MAMMARENAVIRUSES. Lily J. Taylor , Jose A. Rodriguez 835-Pos Board B9 INTERROGATING METAL IDENTITY AND ACTIVE SITE DETAILS IN METAL LOPROTEINS USING COMBINED STRUCTURAL AND SPECTROSCOPIC AP PROACHES. Gabrielle R. Budziszewski, Samantha Arnone, M. Elizabeth Snell, Miranda L. Lynch, Sarah E.J. Bowman 836-Pos Board B10 DISCOVERING THE STRUCTURAL BASIS OF ACTIVATION IN THE TAM RECEPTOR SUBFAMILY. Nicole Fournier , Maria Camila Arango, Lesley Canseco, Skylar Grimsley, Chrystal Starbird 837-Pos Board B11 IDENTIFYING KEY INTERACTIONS OF MONOCLONAL ANTIBODIES THAT TARGET THE HUCOV-HKU1 SPIKE USING CRYOEM. Sheena Vasquez , Lingshu Wang, Jeswin Joseph, Daniel Wrapp, Michael R. Eso, Wing-Pui Kong, Kizzmekia S. Corbett-Helaire, Christopher O. Barnes 838-Pos Board B12 THE CLINICAL MISSENSE VARIANT E282K IN PPP3CA/CALCINEURIN SHIFTS SUBSTRATE DEPHOSPHORYLATION PROFILES BY ALTERING ACTIVE SITE RECRUITMENT. Karina T. Shirakawa , Tvesha Parikh, Hieu Nguyen, Arminja Kettenbach, Wolfgang Peti, Rebecca Page

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