BPS2026 Program Book

Structure and Dynamics of RNA and DNA I (Boards B131 - B158)

971-Pos Board B145 ASSOCIATION OF TETRAPENTYLAMMONIUM WITH THE C-MYG G QUADRUPLEX: A COMBINED NMR AND VOLUMETRIC STUDY. Xuan Li, Mirko Cevec, David Dubins, Janez Plavec, Tigran V. Chalikian 972-Pos Board B146 Travel Award Winner FROM STRUCTURE TO ION ATMOSPHERE TO CONDENSATES: DIVER GENT BEHAVIOR OF POLY(ADP-RIBOSE) VERSUS RNA. Lipika Baidya , Hung T. Nguyen 973-Pos Board B147 NANOPORE AS A LABEL-FREE MOLECULAR RULER FOR RNA PLASTICITY AND SMALL MOLECULE RECOGNITION. Yin-Tzu Chen , Li-Qun Gu 974-Pos Board B148 COARSE-GRAINED INSIGHTS INTO DNA MELTING FROM SECONDARY STRUCTURE-BASED CLUSTERING. Swapnil Baral , Michael Zwolak 975-Pos Board B149 CONSTRUCTING ATOMISTIC RNA ENSEMBLES BY ENHANCED SAMPLING MD SIMULATION. Deng Li , Megan Ken 976-Pos Board B150 SINGLE-MOLECULE ROTOR BEAD STUDY OF DNA PLECTONEME PINNING IN THE PRESENCE OF BASE-PAIR MISMATCHES. Adam Fineberg , Michael Lu, Yasuharu Takagi, Yeonee Seol, Keir C. Neuman 977-Pos Board B151 TOWARD A DESIGN FRAMEWORK FOR CHEMICALLY MODIFIED RNA: INTEGRATING CRYO-EM, FUNCTIONAL ASSAYS, AND MOLECULAR DYNAMICS. Emil Laust Kristoffersen, Nikolaj Zwergius, Nestor Sampedro Vallina, Nicolas Glück, Amanda D. Stange , Lasse M. Desdorf, Laia Civit, Cody Geary, Jørgen Kjems, Julian Valero, Ebbe Sloth Andersen 978-Pos Board B152 CANCELED Travel Award Winner DECODING THE SELF-ASSEMBLY OF MEMBRANE SPANNING DNA CHAN NELS USING MOLECULAR SIMULATIONS. Saanya Yadav , Himanshu Joshi 979-Pos Board B153 MODULATING THE FLUORESCENT LIFETIME OF RIBOGLOW RNA TAGS THROUGH SELEX-DRIVEN MUTATIONS. Zachary Stickelman , Esther Braselmann 980-Pos Board B154 ION PREFERENCES IN RNA STRUCTURE: STABILIZATION OF G:U MIS MATCHES BY POTASSIUM. Hala Ouzon , Anja Henning-Knechtel, Serdal Kirmizialtin, Aleksander Rebane 981-Pos Board B155 STUDY OF SMALL-MOLECULE BINDERS TO A CONSERVED INFLUENZA A VIRUS RNA STUCTURAL MOTIF BY NMR. Ying Emma Zhu , Madhan Kumar Mohan, Gabriele Varani 982-Pos Board B156 Travel Award Winner DRUG REPURPOSING AND MECHANISTIC DISSECTION OF -1 PRO GRAMMED RIBOSOMAL FRAMESHIFTING IN SARS-COV-2. Ahmed Mohamed Ragab Mohamed Sanad , Sui-Yuan Chang, Jin-Der Wen, Lee-Wei Yang 983-Pos Board B157 MECHANISMS OF TRANSLATION INITIATION ON THE STRUCTURED HIV-1 5’ UTR. Crystal I. Stackhouse , Carlos Alvarado, Rosslyn Grosely, Israel Fernández, Joseph D. Puglisi, Elisabetta Viani Puglisi 984-Pos Board B158 MECHANISTIC INSIGHTS INTO HUMAN SCANNING DURING TRANSLA TION INITIATION. Ajinkya Dhepe , Carlos Alvarado, Joseph D. Puglisi

M O N D A Y

957-Pos Travel Award Winner STACKING THE ODDS: INFLUENCE OF SEQUENCE CONTEXT ON DNA BASE STACKING. Ayushi Gupta, Abhinav Banerjee , Mahipal Ganji 958-Pos Board B132 TOWARDS ACCURATE COARSE-GRAINED SIMULATIONS OF PROTEIN/ RNA PHASE SEPARATION. Jianhan Chen 959-Pos Board B133 RNA-BASED SENSING OF METAL IONS AND P H IN GENE EXPRESSION REGULATION. Danea Palmer, Adrien Chauvier, Avery Ontiveros, Christine N. Stephen, Nils G. Walter, Tatiana V. Mishanina 960-Pos Board B134 ENDOGENOUS RNA VISUALIZATION IN LIVE MAMMALIAN CELLS WITH RIBOGLOW-FLIM. Bindu Modi , Esther Braselmann 961-Pos Board B135 ELUCIDATING THE FOLDING AND UNFOLDING DYNAMICS OF ALS AND FTD ASSOCIATED G4C2 MICROSATELLITE REPEAT RNA USING MOLECU LAR SIMULATIONS. Priyanka Yadav , Indranil Malik, Himanshu Joshi 962-Pos Board B136 BIOCHEMICAL AND STRUCTURAL INVESTIGATION OF THE U6 SNRNP AND ITS INTERACTIONS WITH U4 SNRNA. Takuma Kume , Yuichiro No mura, Kaitlyn Abe, Joshua Paulson, Ci Ji Lim, Aaron A. Hoskins, Samuel E. Butcher 963-Pos Board B137 LINKING RNA SEQUENCE TO STRUCTURE AND DYNAMICS THROUGH HIGH-THROUGHPUT SINGLE-MOLECULE FRET AND SEQUENCING (SMFAS). Satya P. Yadav , Julia R. Widom 964-Pos Board B138 CONFIGURATIONAL TEMPERATURE AND ENTROPY CHANGES OF RNA UNFOLDING FROM BROWNIAN DYNAMICS SIMULATIONS. Mario Villada-Balbuena, Mauricio D. Carbajal-Tinoco 965-Pos Board B139 MECHANISM OF HCV 3’X RNA DIMERIZATION. Erik D. Holmstrom , Parker Sperstad 966-Pos Board B140 TRACKING POLYADENYLATION OF SINGLE PRE-MRNA MOLECULES USING FLUORESCENT PROBES. Brielle Lauber , Ethan Aubuchon, Holly Fagarasan, Lori Passmore, Aaron A. Hoskins 967-Pos Board B141 LINKING CONFORMATIONAL DYNAMICS OF KRAS G-QUADRUPLEXES TO LIGAND IDENTIFICATION. Rakshitha Hosahalli , Azaan Dawson, Haley Michel, Justin A. Lemkul 968-Pos Board B142 INTRAGENOMIC RNA-RNA CONTACTS WITHIN THE HEPATITIS C VIRUS MODULATE THE CONFORMATIONS OF 3′X RNA. Ethan P. Rogers , Parker Sperstad, Erik D. Holmstrom 969-Pos Board B143 UNRAVELING THE STRUCTURAL COMPLEXITIES OF NON-CANONICAL DNA CONFORMATIONS USING FLUORESCENT BASE ANALOGS. Mack lin Jugan, Samantha Lecrone, Noureen Qureshi, Matthew Finkelstein, Daniel Flynn, Davis Jose 970-Pos Board B144 A THEORY OF L: SINGLE-MOLECULE FRAGMENTATION OF DNA. Michael Zwolak , Joseph W. Robertson Board B131

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