BPS2026 Program Book

Platform Mechanosensitive, Anion, and Other Channels 8:15 am - 10:15 am, Room 204/205/206 Co-Chairs Hubert Lee, NIDCD, NIH, USA Mindaugas Snipas, Kaunas University of Technology, Lithuania 1294-Plat 8:15 am ASSEMBLY AND LIPID-GATING OF LRRC8A:D VOLUME-REGULATED ANION CHANNELS. Antony Lurie , Christina A. Stephens, David M. Kern, Katharine Henn, Naomi R. Latorraca, Steve G. Brohawn 1295-Plat 8:30 am Travel Award Winner ARACHIDONIC ACID INHIBITION OF TMEM16A CHANNELS. Crystal J. Lara Santos , Yisheng Zheng, Christina A. Stephens, Kayla M. Komondor, Scott A. Hahn, Adam C. Straub, Michael Grabe, Anne E. Carlson 1296-Plat 8:45 am MATHEMATICAL MODELING OF GAP JUNCTION CHANNEL VOLTAGE GATING: FROM SINGLE CHANNELS TO EXCITABLE TISSUES. Mindaugas Snipas , Tadas Kraujalis, Lukas Gudaitis, Orestas Makniusevicius, Kestutis Maciunas, Lina Kraujaliene, Vytas Verselis 1297-Plat 9:00 am EXTRACELLULAR MATRIX PROTEINS SUPPRESS DEG/ASIC/ENAC CHAN NEL MEC-4 ACTIVITY. Joseph W. Nors , Austin Chan, Tsuyoshi Ozaki, Miriam B. Goodman 1298-Plat 9:15 am TURGOR-DRIVEN RECOVERY OF THE BACTERIAL MECHANOSENSITIVE CHANNEL MSCS LEADS TO ITS COMPACT CLOSED STATE. Andriy Anish kin, Kenjiro Yoshimura, Elissa Moller, Madolyn Britt, Sergei I. Sukharev 1299-Plat 9:30 am TMC1 AND TMC2 ARE CHOLESTEROL-DEPENDENT SCRAMBLASES THAT REGULATE MEMBRANE HOMEOSTASIS IN AUDITORY HAIR CELLS. Hu bert Lee , Yein Christina Park, Jayashree Balaraman, Angela Ballesteros 1300-Plat 9:45 am Travel Award Winner FUNCTIONAL HETEROMERIZATION OF MAMMALIAN PIEZO CHANNELS. Aneesh Chandrasekharan , Tharaka D. Wijerathne, Ipek Midillioglu, Roshiel D. Guzman, Ariga Tahmasian, Louis-Philippe Guinard, Michelle Digman, Jerome J. Lacroix 1301-FlashTalk 10:00 am Travel Award Winner A TRAP-AND-RELEASE MECHANISM DRIVES VOLTAGE-DEPENDENT TRANSPORT IN A LARGE-PORE CHANNEL. Pablo S. Gaete , Cynthia I. Fernandez, Deepak Kumar, Yun Lyna Luo, Jorge E. Contreras 1302-FlashTalk 10:05 am Travel Award Winner THE FLUORESCENT NONCANONICAL AMINO ACID ACRIDONYLALANINE REPORTED CONFORMATIONAL CHANGES IN THE HUMAN VOLTAGE GATED PROTON CHANNEL (H V 1). Emerson M. Carmona , Charlie DeFre est, William N. Zagotta, Sharona E. Gordon 1303-FlashTalk 10:10 am MSCM USES A NOVEL GATING MECHANISM FOR BACTERIAL MECHANO SENSITIVE CHANNELS. Giorgos Hiotis , Thomas Walz

Platform Protein-Nucleic Acid Interaction II 8:15 am - 10:15 am, Room 207/208

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Co-Chairs Jun-tao Guo, University of North Carolina at Charlotte, USA Qilan Wei, Johns Hopkins University, USA 1304-Plat 8:15 am Travel Award Winner METHYLTRANSFERASE RSMB CHAPERONES E. COLI RIBOSOME ASSEM BLY BY ORCHESTRATING THE RECRUITMENT OF RIBOSOMAL PROTEINS. Qilan Wei , Sarah A. Woodson 1305-Plat 8:30 am VISUALIZATION OF DOUBLE-HEXAMERIC MCM IN CELLULO USING MINFLUX NANOSCOPY. Jonas Zaehringer , Oraya J. Zinder, Supriya G. Prasanth, Taekjip Ha 1306-Plat 8:45 am STUDIES OF HUMAN TOPOISOMERASE DYNAMICS USING FLOW MAG NETIC TWEEZERS. Filip Filipovic , James Berger, Karl E. Duderstadt 1307-Plat 9:00 am MULTI-STEP FOLDING OF DNA BY SARS-COV-2 NUCLEOCAPSID PROTEIN. Theint Theint Thu , Jonathan M. Xing, Jimmy Lin, Katherine Martini, Ashley Carter 1308-Plat 9:15 am THERMODYNAMIC INFLUENCE OF CATIONIC CLUSTER SIZE ON PROTEIN ASSISTED NUCLEIC ACID FOLDING. Gabrielle Perkins , Parnian Arafi, Kathryn Lebold, Erik D. Holmstrom 1309-Plat 9:30 am COMPARATIVE ANALYSES OF HYDROGEN BOND ENERGY IN PROTEIN DNA INTERACTIONS. Vedika Jeswani Judyani, Thu Vang, Julian Aileru, Jun-tao Guo 1310-Plat 9:45 am CHROMATIN BUFFERS TORSIONAL STRESS DURING TRANSCRIPTION. Jin Qian , Lucyna Lubkowska, Shuming Zhang, Chuang Tan, Yifeng Hong, Xiaomeng Jia, Robert M. Fulbright, James T. Inman, Taryn M. Kay, Joshua Jeong, Glenn Hauk, Deanna Gotte, James M. Berger, Mikhail Kashlev, Travel Award Winner CORRELATED DYNAMICS AND ACTIVITY MAPPING (C-DAM) REVEALS RAPID DNA POLYMERASE EXCHANGE AND SSB DISPLACEMENT AT THE REPLICATION FORK. Longfu Xu , Zhaowei Liu, Colleen Caldwell, Shyla Singh, Matthew T. Halma, Gijs J. Wuite 1312-FlashTalk 10:05 am Travel Award Winner PARBS CONDENSATES GENERATE FORCE FOR BACTERIAL CHROMO SOME SEGREGATION. Ritika Gupta , Xinyue Song, Suleyman Ucuncuo glu, W. Seth Childers, David Dunlap, Laura Finzi 1313-FlashTalk 10:10 am STRUCTURES OF CAS9-BOUND DOUBLE-STRANDED DNA MIMI-CIRCLE REVEAL IMPACTS OF DNA SHAPE ON CRISPR-CAS9 TARGET INTERROGA TION. Kyu-Yeon Lee, Donggyun Kim, Yukang Liu, Hongjian Chang, Vadim Cherezov, Jiansen Jiang, Peter Z. Qin Michelle D. Wang 1311-FlashTalk 10:00 am

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