BPS2026 Program Book

1414-Plat 4:15 pm ESPRESSO: SPATIOTEMPORAL OMICS BASED ON ORGANELLE PHENO TYPING REVEALS DYNAMIC CELL STATE TRANSITIONS. Lorenzo Scipioni , Giulia Tedeschi, Mariana Navarro, Yunlong Jia, Songning Zhu, Lila P. Hal bers, Melody Di Bona, Scott Atwood, Jennifer Prescher, Enrico Gratton, Michelle A. Digman 1415-Plat 4:30 pm DIRECT VISUALIZATION OF ER-ASSOCIATED DEGRADATION BY MUL TICOLOR SINGLE MOLECULE TRACKING. Tim Abel , Lilly Castorena, Brandon M. Liu, Sonya E. Neal, Christopher J. Obara 1416-Plat 4:45 pm VDAC ISOFORM-SPECIFIC MODULATION OF MITOCHONDRIA STRUC TURE AND FUNCTION. Nina A. Bautista , Jennifer D. Petersen, Wendy Fitzgerald, Sergey M. Bezrukov, Tatiana K. Rostovtseva, Megha Rajen dran 1417-Plat 5:00 pm ESTROGEN RECEPTOR MODULATORS AFFECT MITOCHONDRIAL PHYSI OLOGY THROUGH THE VOLTAGE-DEPENDENT ANION CHANNEL. Mya S. Wolfe , Sergey M. Bezrukov, Tatiana K. Rostovtseva, Wendy K. Fitzgerald, Megha K. Rajendran, Martha Bosch, Scotty Farley, Per Haberkant, Frank Stein, Carsten Schultz, Martin Kelley 1418-Plat 5:15 pm CRYO-ET OF THE HARPOON-LIKE INVASION APPARATUS FROM MICRO SPORIDIAN PARASITES. Mahrukh Usmani, Nicolas Coudray, Margot Riggi, Rishwanth Raghu, Daija Bobe, Mykhailo Kopylov, Paris Watson, Ellen Zhong, Janet Iwasa, Gira Bhabha, Damian C. Ekiert 1419-Plat 5:30 pm DETERMINING MECHANISMS UNDERLYING NUCLEAR SIZE CONTROL IN FISSION YEAST. Joël Lemiere , Fred Chang 1420-FlashTalk 5:45 pm COMPUTATIONAL INSIGHTS INTO THE MOLECULAR BASIS OF HIGH LIGHT ADAPTATION IN CYANOBACTERIA AND CYANOPHAGES WITHIN PHOTOSYSTEM II. Rulong Ma, Suman Samantray, Mazen Malak, Amity Andersen, Greg Morrison 1421-FlashTalk 5:50 pm PTPIP51 MEDIATES MITOCHONDRIAL-SARCOPLASMIC RETICULUM AP PROXIMATION AFTER MYOCARDIAL INFARCTION. An Xie , Gyeoung-Jin Kang, Eun Ji Kim, Samuel C. Dudley 1422-FlashTalk 5:55 pm INVESTIGATING DNA DAMAGE AS A FUNCTION OF VARYING RADIATION DOSE RATES ON NORMAL AND MALIGNANT MAMMARY EPITHELIAL CELLS. Simruthi Subramanian , Savannah Kidd, Natalia Molchanova, Behzad Rad, Jared de Chant, Aodhan McIlvenny, Anthony Lu, Kei Naka mura, Lieselotte Obst-Huebl, Corie Y. Ralston, Jamie Inman Platform Structure and Dynamics of RNA and DNA 4:00 pm - 6:00 pm, Room 209/210/211 Co-Chairs Pablo D. D. Dans Puiggròs.University of the Republic, Uruguay Amanda Stange, Aarhus University, Denmark 1423-Plat 4:00 pm SINGLE-MOLECULE ROTOR BEAD STUDY OF DNA PLECTONEME PINNING IN THE PRESENCE OF BASE-PAIR MISMATCHES. Adam Fineberg , Michael Lu, Yasuharu Takagi, Yeonee Seol, Keir C. Neuman

1424-Plat 4:15 pm TOWARD A DESIGN FRAMEWORK FOR CHEMICALLY MODIFIED RNA: INTEGRATING CRYO-EM, FUNCTIONAL ASSAYS, AND MOLECULAR DYNAMICS. Emil Laust Kristoffersen, Nikolaj Zwergius, Nestor Sampedro Vallina, Nicolas Glück, Amanda D. Stange , Lasse M. Desdorf, Laia Civit, Cody Geary, Jørgen Kjems, Julian Valero, Ebbe Sloth Andersen 975-Pos 4:30 pm CONSTRUCTING ATOMISTIC RNA ENSEMBLES BY ENHANCED SAMPLING MD SIMULATION. Deng Li , Megan Ken 1426-Plat 4:45 pm MODULATING THE FLUORESCENT LIFETIME OF RIBOGLOW RNA TAGS THROUGH SELEX-DRIVEN MUTATIONS. Zachary Stickelman , Esther Braselmann 1427-Plat 5:00 pm STUDY OF SMALL-MOLECULE BINDERS TO A CONSERVED INFLUENZA A VIRUS RNA STUCTURAL MOTIF BY NMR. Ying Emma Zhu , Madhan Kumar Mohan, Gabriele Varani 1428-Plat 5:15 pm Travel Award Winner DRUG REPURPOSING AND MECHANISTIC DISSECTION OF -1 PRO GRAMMED RIBOSOMAL FRAMESHIFTING IN SARS-COV-2. Ahmed Mohamed Ragab Mohamed Sanad , Sui-Yuan Chang, Jin-Der Wen, Lee-Wei Yang 1429-Plat 5:30 pm GEEMELD: IN SILICO FOLDING OF DNA G-QUADRUPLEX GUIDED BY CIRCULAR DICHROISM AND PAIRING RULES. Pablo D. Dans Puiggròs , Jokent Gaza, Santiago Pintos, Ari Zeida, Victoria Calzada, Gabriela da Rosa, Alberto Perez 1430-FlashTalk 5:45 pm MECHANISMS OF TRANSLATION INITIATION ON THE STRUCTURED HIV-1 5’ UTR. Crystal I. Stackhouse , Carlos Alvarado, Rosslyn Grosely, Israel Fernández, Joseph D. Puglisi, Elisabetta Viani Puglisi 1431-FlashTalk 5:50 pm MECHANISTIC INSIGHTS INTO HUMAN SCANNING DURING TRANSLA TION INITIATION. Ajinkya Dhepe , Carlos Alvarado, Joseph D. Puglisi 1432-FlashTalk 5:55 pm ION PREFERENCES IN RNA STRUCTURE: STABILIZATION OF G:U MIS MATCHES BY POTASSIUM. Hala Ouzon , Anja Henning-Knechtel, Serdal Kirmizialtin, Aleksander Rebane Platform Co-Chairs Briar Bell, University of Texas Health Science Center, USA Rebecca J. Howard, Stockholm University, Sweden 1433-Plat 4:00 pm Travel Award Winner FUNCTIONAL AND STRUCTURAL BASIS OF A TRPC3-MEDIATED CEREBEL LAR ATAXIA. Briar Bell , Angela M. Jaramillo Granada, Luis O. Romero, Irene A. Gutierrez, Venkata K.P.S. Mallampalli, Guizhen Fan, Sameer Varma, Matthew L. Baker, Irina I. Serysheva, Valeria Vásquez, Julio F. Cordero-Morales 1434-Plat 4:15 pm Travel Award Winner DIFFRACTED X-RAY TRACKING REVEALS LIGAND- AND TEMPERATURE DEPENDENT C-TERMINAL DYNAMICS OF TRPM8. Haruto Machida , Tatsunari Ohkubo, Daisuke Sasaki, Hiroshi Sekiguchi, Kazuhiro Mio, Yuji C. Sasaki TRP and Ligand-gated Channels 4:00 pm - 6:00 pm, Room 212/213/214

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