BPS2026 Program Book

1542-Pos Board B79 MORE THAN A SHIELD: GLYCANS MODULATE TILTING DYNAMICS OF THE HIV-1 ENV GLYCOPROTEIN. Mohamed Shehata , Lorenzo Casalino, Madeleine C. Duquette, Siyu Chen, Alex Flaherty, Elizabeth Villa, Rom mie E. Amaro 1543-Pos Board B80 PROTEIN DRIFT-DIFFUSION IN BIOLOGICALLY ACTIVE MEMBRANES WITH NON-EQUILIBRIUM FLUCTUATIONS. Paul J. Atzberger 1544-Pos Board B81 SPATIOTEMPORAL ORGANIZATION OF MEMBRANE PROTEIN FOR BAC TERIAL EXTRACELLULAR ELECTRON TRANSFER. Youngchan Park 1545-Pos Board B82 MODELING-INFORMED EXPERIMENTS CAPTURE ARC-LIPID INTERAC TIONS CRITICAL TO INTERCELLULAR COMMUNICATION. Bryan Gworek , Kritika Mehta, Henry Yentsch, Taras V. Pogorelov, Kai Zhang 1546-Pos Board B83 PROBING MYOMAKER’S MECHANISM OF ACTION THROUGH MOLECU LAR DYNAMICS SIMULATIONS. Laura J.S. Lopes , Tanner J. Wherley, Douglas P. Millay, Alexander J. Sodt 1547-Pos Board B84 GATING PRINCIPLES OF PROTON TRANSPORT IN DISSECTED MODULES OF RESPIRATORY COMPLEX I. Sofia Badolato 1548-Pos Board B85 INTEGRATIVE INVESTIGATION OF THE LONG-RANGE COUPLING IN E. COLI COMPLEX I. Adel Beghiah 1549-Pos Board B86 RECONSTITUTION OF RAS-PI3KΓ MEMBRANE COMMUNICATION AND FEEDBACK USING LIGHT-INDUCED SIGNALING INPUTS. Scott D. Hansen , Sophia Doerr, Andres Olavarrieta-Colasurdo Intrinsically Disordered Proteins III (Boards B87 - B107) 1550-Pos Board B87 EARLY-STAGE INTERACTIONS AND CO-ASSEMBLY MECHANISMS OF HU MAN AMYLOID-Β AND AMYLIN. Akshay N. Sarangi , Utkarsh Sinha, Amar Nath Gupta 1551-Pos Board B88 INHIBITION OF Α-SYNUCLEIN AGGREGATION BY NANO-FORMULATION OF POLYPHENOLS IN NANO 2 -INDUCED PARKINSON’S DISEASE. Abhinav Prasad , Shashank Deep 1552-Pos Board B89 CHARACTERIZATION OF THE TAU-SOCS4 INTERACTION. Manasi Movva , Avi Samelson 1553-Pos Board B90 AHEAD OF THE MEMBRANE CURVE: IN SILICO INSIGHTS INTO AMYLOID ΒETA AGGREGATION. Pedro Maximiano Santos , Mohtadin Hashemi 1554-Pos Board B91 ATOMIC STUDY OF BINDING MECHANISM OFPARAMAGNETIC AMYLOID LIGAND TO Α-SYNUCLEIN. Hung-Yu Wan 1555-Pos Board B92 CONFORMATIONAL STRUCTURE AND INTERFACIAL MECHANISMS PROVIDE A MOLECULAR RATIONALE FOR THE PHENOTYPIC DIVERGENCE OF THE FAMILIAL ALZHEIMER’S DISEASE A2V MUTATION. Lucy J. Hayes , Zhenzhen Zhang, Feng Ding

1556-Pos Board B93 NEUROTRANSMITTER CHEMICAL STRUCTURE DICTATES BETA-SYNU CLEIN AGGREGATION PROPENSITY: FROM POLYMORPHIC FIBRILS TO AGGREGATION ARREST. MD Wamique Hossain , Rajiv Bhat 1557-Pos Board B94 CATALYTIC ACTIVITY OF Α-SYNUCLEIN AMYLOIDS DEPENDS ON STRUC TURAL MOTIFS AND METAL IONS. Fiamma Ayelen Buratti , Pernilla Wittung-Stafshede 1558-Pos Board B95 COMPENSATORY EFFECTS OF THE DISORDERED REGION OF HUMAN PARATHYROID HORMONE ON AMYLOID AGGREGATION IN CROWDED ENVIRONMENT. Twinkle Bhatia , Shubhra Sachan, Jochen Balbach, Board B96 MOLECULAR DYNAMICS SIMULATIONS OF METABOLITES AND PEPTIDE FIBRILS. Pavel Rehak , Lela Vukovic, Petr Kral 1560-Pos Board B97 MALVIDIN MODULATES FIBRILLATION KINETICS AND FIBRIL MORPHOL OGY OF THE E46K ALPHA SYNUCLEIN MUTANT: IMPLICATIONS FOR PARKINSON’S DISEASE THERAPEUTICS. Mani Gupta , Rajiv Bhat 1561-Pos Board B98 INVESTIGATING THE EFFECT OF CHOLESTEROL ON AMYLOID-Β PEPTIDE INTERACTION WITH MEMBRANE USING MOLECULAR DYNAMICS SIMU LATIONS. Yiru Qian , Esmael J. Haddadian 1562-Pos Board B99 COMPUTATIONAL INVESTIGATION OF THE ROLE OF THE ANTI-DIA BETIC DRUG METFORMIN AND ITS ANALOGUES IN MODULATING Α-SYNUCLEIN AGGREGATION. Debasis Saha , Xue Wang, Jinghui Luo, Wenwei Zheng 1563-Pos Board B100 Travel Award Winner DISSECTING THE INTERPLAY OF TDP-43 AND TAU IN HETEROTYPIC PHASE SEPARATION AND AGGREGATION. Anuja Walimbe , Snehasis Sarkar, Roopali Khanna, Arpita Singh, Deepti D. Ramteke, Ashish Joshi, Mahak Sharma, Samrat Mukhopadhyay 1564-Pos Board B101 LIQUID-LIQUID PHASE SEPARATION MODULATES PROTEIN PATHOLOGI CAL AGGREGATION. Yi Shen , Tuomas P. Knowles, David A. Weitz, Daniele Vigolo, Tianchen Li, Dea Ilhamsyah 1565-Pos Board B102 Α-SYNUCLEIN INTERACTIONS WITH LIPID MEMBRANES: COOPERATIVE BINDING AND MEMBRANE REMODELLING. Noemi Ferrante Carrante , Marija Dubackic, Katarzyna Makasewicz, Stefan Wennmalm, Nicole Galenkamp, Tova Hermodsson, Katja Bernfur, Sara Linse, Emma Sparr 1566-Pos Board B103 ARE SHORT PEPTIDES OR COIL LIBRARIES OF PROTEINS SUITABLE MODEL SYSTEMS FOR DETERMINING THE COIL STATE OF INTRINSICALLY DISORDERED PROTEINS (IDPS)? Reinhard Schweitzer-Stenner 1567-Pos Board B104 IMPACT OF MEMBRANE PHASE AND CHARGE ON ALPHA SYNUCLEIN BINDING. Orianna Kou , Cailyn Sakurai, Christopher T. Lee, Wade F. Zeno 1568-Pos Board B105 THE POLY-E MOTIF OF TITIN EXHIBITS GREATER MECHANICAL COMPLI ANCE AT ACIDIC PH. Prasan M. Wijayaweera , Chris Tiessen, Walter Herzog, Matthew J. Gage Maria Ott 1559-Pos

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