BPS2026 Program Book

1592-Pos Travel Award Winner PROBING SEQUENCE - SPECIFIC DNA HYBRIDIZATION DYNAMICS US ING THERMO-SPARXS. Naveen Kumar , Carolien Bastiaanssen, Patrick Irmisch, Archana Sivaraman, Patrick Engelmann, Nicole Weizenmann, Henri G. Franquelim, Chirlmin Joo, Ralf Seidel 1593-Pos Board B130 EXPANDING THE APPLICABLE FORCE RANGE IN OPTICAL TWEEZERS BY COVALENT COUPLING TO PROBE THE ONCOGENE PROMOTER C KIT1. Carina Wrobel , Daniel Bublitz, Luis Guillermo Moreno Alcantar, Angela Casini, Matthias Rief 1594-Pos Board B131 CHARACTERIZATION OF G-QUADRUPLEX STRUCTURES IN THE SHMT1 5’UTR: IMPLICATIONS FOR REGULATING METHYLATION IN MULTIPLE SCLEROSIS. Rosalia Palumbo , Manju Kasaju, Sophia Hershey, Morgan McCann, David Heisler, Mihaela-Rita Mihailescu 1595-Pos Board B132 GENERAL MECHANISMS OF R-LOOP FORMATION AT DNA DOUBLE STRAND BREAKS. Gunhyoung Lim , Dongwon Joo, Sungchul Hohng 1596-Pos Board B133 EXPRESSING MEMBRANE-LESS RNA ORGANELLES IN LIPID-BASED SYNTHETIC CELLS. Akthar Hussain Mougamadou Soultane , Roger Rubio-Sánchez, Nada Farag, Maya Mueller, Giacomo Fabrini, Marina K. Kuimova, Lorenzo Di Michele 1597-Pos Board B134 ELUCIDATING THE ROLE OF THE HNRNP K MRNA 3’-UTR G-QUADRU PLEX STRUCTURE IN MEDIATING ITS INTERACTIONS WITH MIR-1249 3P. Manju Kasaju , Rosalia Palumbo, Bryan Kelleher, Carlan Gray, Jacob Shoulders, David B. Heisler, Mihaela-Rita Mihailescu 1598-Pos Board B135 CHARACTERIZING LOW-ABUNDANCE RNA “EXCITED” STATES IN THE HIV 1 5’-UNTRANSLATED REGION. Linshu Li , Jessica Vance, Deng Li, Megan Ken 1599-Pos Board B136 BIOPHYSICAL CHARACTERIZATION OF A G-QUADRUPLEX STRUCTURE IN PRE-MIR-615: IMPLICATIONS FOR MIR-615 MATURATION. Gabriela Garza , Petru Mihailescu, George Calin, Mihaela-Rita Mihailescu 1600-Pos Board B137 MODELING ELUCIDATES VARIABLE IMPACT OF SMALL MOLECULE PROBES ON A SPLICEOSOMAL U4/U6 SMALL NUCLEAR RNA STRUCTURE IN YEAST. Wojciech K. Kasprzak , Mo Yang, Shaifaly Parmar, Sumirtha Balaratnam, Desta D. Bume, John S. Schneekloth, Jr. 1601-Pos Board B138 SYNTHESIZING SUPERCOILED CIRCULAR DNA MOLECULES IN VI TRO . Fenfei Leng , Sepideh Rezaei, Monica Moncada-Restrepo, Sophia Leng, Jeremy W. Chambers 1602-Pos Board B139 CHARACTERIZATION OF AN IMMUNE GENE PRIMING LNCRNA AND ITS INTERACTION WITH WDR5. Amy Crawford , Alisha Jones Protein-Nucleic Acid Interaction I (Boards B140 - B168) 1603-Pos Board B140 RNA BINDING SITES IN CANONICAL AND MOONLIGHTING RNA BIND ING PROTEINS. Trang Tu, Geordie Emberling, Tina Harati, Nicole Curtis, Alquama Lokhandwala, Ganesan Murugan, Kyle Zhang, Thomas Wayles, Mary Jo Ondrechen, Constance Jeffery Board B129

1604-Pos Board B141 LEDGF AND HDGF2 DIFFERENTIALLY REMODEL HISTONE-DNA INTERAC TIONS IN H3K36 METHYLATION-MIMETIC NUCLEOSOMES. Joha Joshi , Micah J. McCauley, Michael Morse, Zelin Shan, Tao Jing, Gennavieve Gray, Nicole A. Becker, Ioulia F. Rouzina, Louis J. Maher, Dmitry Lyumkis, Mark C. Williams 1605-Pos Board B142 NUCLEOSOME STABILITY IS CONTROLLED BY HISTONE COMPOSITION AND FINE TUNED BY DNA SEQUENCE. Jose Ignacio Perez-Lopez , Maria Julia Maristany, Jan Huertas Martin, Rosana Collepardo-Guevara 1606-Pos Board B143 DNA CONDENSATION STABILIZES THE BINDING OF HIV-1 NUCLEOCAPSID PROTEIN TO PROMOTE PHASE SEPARATION AND INHIBIT DECONDENSA TION. Michael Morse , Helena Hall, Micah J. McCauley, Ioulia Rouzina, Mark C. Williams 1607-Pos Board B144 SINGLE-MOLECULE STUDIES REVEAL THAT THE DNA SENSOR IFI16Β INHIBITS AIM2 INFLAMMASOME VIA DNA COMPETITION. Sneha Bhat , Joshua Thomas, Eva de Alba 1608-Pos Board B145 A CONSERVED DIMERIZATION INTERFACE OF SUPERFAMILY 1A HELICAS ES. Binh Nguyen , Ankita Chadda, Eric A. Galburt, Timothy M. Lohman 1609-Pos Board B146 SULFOLOBUS SOLFATARICUS SEGC REGULATES SEGROSOME FORMA TION AND PARTICIPATES IN ARCHAEAL CHROMOSOME SEGREGA TION. Chwan-Deng Hsiao , Min-Guan Lin, Yuh-Ju Sun 1610-Pos Board B147 DECIPHERING THE TRANSLOCATION AND UNWINDING MECHANISM OF THE CHL1 DNA HELICASE. Hajnalka Harami-Papp , Gabor Harami, Peter Burkovics, Dana Branzei, Keir C. Neuman 1611-Pos Board B148 INVESTIGATING THE HISTONE-TO-PROTAMINE REPLACEMENT PATH WAY. Andrea Yan , Stan D. Craig, Ashley R. Carter 1612-Pos Board B149 USING HISTONE REPLACEMENT-INDUCED DNA FOLDING TO DECODE MALE INFERTILITY. Stan D. Craig , Andrea Yan, Ashley R. Carter 1613-Pos Board B150 CROSS-LINKED E.COLI UVRD DIMERS ARE CONSTITUTIVELY ACTIVATED HELICASES AND SHOW INCREASED SSDNA TRANSLOCATION PROCESSIV ITY. Kacey N. Mersch , Binh Nguyen, Eric A. Galburt, Timothy M. Lohman 1614-Pos Board B151 COMPUTATIONAL MODELLING OF RNA-PROTEIN BINDING INTERAC TIONS UNDER AN EXTERNAL FORCE. Danielle Wampler , Ralf Bundschuh 1615-Pos Board B152 RNA POLYMERASE II IS A POLAR ROADBLOCK TO A PROGRESSING DNA FORK. Taryn M. Kay , James T. Inman, Lucyna Lubkowska, Tung T. Le, Jin Qian, Porter M. Hall, Sahil Batra, Dirk Remus, Dong Wang, Mikhail Kashlev, Michelle D. Wang 1616-Pos Board B153 RELATIVE PROTEIN-NUCLEIC ACID BINDING FREE ENERGY DIFFERENCES USING THE POLARIZABLE AMOEBA FORCE FIELD. Jacob M. Miller, Michael J. Schnieders 1617-Pos Board B154 CAG REPEATS RESHAPE RNA POLYMERASE II DYNAMICS IN THE ELONGA TION COMPLEX. Adan Gallardo Maciel , Bercem Dutagaci

T U

E S

D A Y

124