BPS2026 Program Book

1874-Pos Board B411 TDP-43 AMYLOID FILAMENT CAPPING THROUGH A COMPUTATIONAL MICROSCOPE. Jeevapani J. Hettige , Jianzheng Wu, Alex Von Schulze, Randal Halfmann 1875-Pos Board B412 MEMBRANE INTERACTIONS STABILIZE AND SCAFFOLD THE RPE65 CATA LYTIC DIMER. Daniel E. Santos , Philip Kiser, Alvin Yu 1876-Pos Board B413 MODELLING HUMAN ΓD-CRYSTALLIN AGGREGATION FOR CATARACT TREATMENT USING COMPUTATIONAL METHODS. Kaiden Zaborowski 1877-Pos Board B414 DEVELOPMENT AND BENCHMARKING OF THE OPEN FORCE FIELD INITIATIVE SELF-CONSISTENT FORCE FIELD FOR PROTEINS AND SMALL MOLECULES. Chapin E. Cavender , Irfan Alibay, Pavan K. Behara, Jennifer A. Clark, Anika J. Friedman, Julianne Hoeflich, Joshua T. Horton, Louis G. Smith, Matthew W. Thompson, Jeffrey Wagner, Lily Wang, John D. Chodera, Daniel J. Cole, David L. Mobley, Michael R. Shirts, Michael K. Gilson 1878-Pos Board B415 Travel Award Winner COMPUTATIONAL DESIGN OF MATRIX METALLOPROTEINASE-9 (MMP-9) INHIBITORS AS POTENTIAL CANCER THERAPEUTICS. Makda Gebreegziabher , Bill Miller, Dagmawit Kebede, Haleluya Merga 1879-Pos Board B416 DIRECT 3D INTRACELLULAR DIFFUSION MEASUREMENT WITH DUAL CHANNEL PHASE MASK LIGHT SHEET FLUORESCENCE MICROSCOPY IN S. CEREVISIAE. Alex A. Castelblanco , Luis C. Bastidas, Luisa M. Aristizabal, David C. Duran, Manu Forero-Shelton 1880-Pos Board B417 MECHANISM OF AMYLOID Β-PEPTIDE (AΒ) DISSOCIATION FROM Γ-SECRETASE COMPLEX. Keya Joshi Computational Methods and Machine Learning, Artificial Intelligence, and Bioinformatics II (Boards B418 - B446) 1881-Pos Board B418 Travel Award Winner ALLOSTERIC INHIBITION OF MATRIX METALLOPROTEINASE 9 (MMP-9) IN SILICO . Haleluya Merga , Dagmawit Kebede, Makda Gebreegziabher, Board B419 UNRAVELING SPECTRAL SHIFTS IN MICROBIAL RHODOPSIN THROUGH MACHINE LEARNING PREDICTIONS AND MOLECULAR DYNAMICS SIMU LATIONS. Shubham K. Pandey , Aajinkya Naik, Jagdish S. Patel 1883-Pos Board B420 GEOMETRY-AWARE RNA-SMALL MOLECULE BINDNIG SITE PREDICTION WITH EQUIVARIANT GRAPH NEURAL NETWORK. JinHyeok Yoo 1884-Pos Board B421 ANALYZING THE AUXILIAROME: STRUCTURAL INSIGHTS INTO AUXILIARY MEMBRANE PROTEINS AND THEIR BINDING PARTNERS. Matthew S. Smith , Naomi R. Latorraca 1885-Pos Board B422 SOME APPLICATIONS OF AI TO BIOMOLECULES FOR BOTH ANSWERS AND INSIGHT. Darrin Bath, Bruno Mochi, Mary Jo Ondrechen 1886-Pos Board B423 DIFFUSION MODEL PROPOSALS ACCELERATE MOLECULAR DYNAMICS WHILE PRESERVING ENSEMBLE FIDELITY. Pavan Subramani , Joseph Torsiello Bill Miller 1882-Pos

1887-Pos Board B424 CHARMM-GUI QUICK BILAYER: SIMPLE AND INTUITIVE ONE-STOP MEM BRANE BUILDER. Sang-Jun Park , Wonpil Im 1888-Pos Board B425 LEVERAGING TRANSCRIPTOMIC SIGNATURES AND MACHINE LEARN ING TO PREDICT HIGH RISK PROGRESSION IN HPV RELATED CERVICAL LESIONS. Demilade S. Ajifa , Roshan Paudel 1889-Pos Board B426 SPATIAL CORRELATIONS OF SINGLE-CELL GENE EXPRESSIONS. Ankita Sarkar , Sankha Subhra Chakrabarty 1890-Pos Board B427 LOCATING MACROMOLECULES WITHIN CROWDED CELL ENVIRON MENTS WITH DEEP REPRESENTATION LEARNING. Kithmini K. Herath , Bronwyn Lucas 1891-Pos Board B428 FOURIER-NET: A “ONE-STOP SHOP” FOR CV GENERATION AND FEATUR IZATION. Amun C. Patel , Mohd Ahsan, Giulia Palermo 1892-Pos Board B429 MACHINE LEARNING ANALYSIS OF CELLULAR REMODELING DURING OC CLUSIVE BLOOD CLOT FORMATION. Cameron Baenen , Samuel J. Fulton, Irina Pokrovskaya, Maria Aronova, Brian Storrie, Richard D. Leapman 1893-Pos Board B430 Travel Award Winner ALICEDB: A VARIANT-AWARE PROTEOMIC DATABASE AND ANALYSIS PIPELINE FOR BIOMARKER DISCOVERY. Inez Mruk , Marcel Thiel, Michal Puchalski, Alicja Rózycka, Stanislaw Oldziej, Paulina Czaplewska 1894-Pos Board B431 DYNAMICS OF AMINO ACID SIDE-CHAIN PACKING REVEALED BY VOR ONOI ANALYSIS OF SIMULATION TRAJECTORIES. Sofiya B. Bettencourt , Wonmuk Hwang 1895-Pos Board B432 A MACHINE LEARNING FRAMEWORK FOR PREDICTING CD4⁺ T-CELL RECEPTORS’ THERAPEUTIC EFFICACY FROM STRUCTURAL AND DYNAMI CAL FEATURES. Stella Lee , Lauren Wu, Esmael J. Haddadian 1896-Pos Board B433 LEARNING JUMP DISTANCE DISTRIBUTIONS WITH NORMALIZING FLOWS. Jay C. Spendlove , Weiqing Xu, Pedro Pessoa, Steve Pressé 1897-Pos Board B434 COMBINING ISM AND FLIM FOR HIGH-FIDELITY LIFETIME IMAGING IN DENSE ENVIRONMENTS. Max Tillmann, Anders Barth , Matthias Patting, Felix Koberling, Rainer Erdmann 1898-Pos Board B435 DETERMINING BINDING OF THE YEAST KILLER TOXIN K1 WITH ITS MEM BRANE RECEPTOR KRE1. Linus Kittan , F. Marty Ytreberg 1899-Pos Board B436 A DYNAMICAL SYSTEMS FRAMEWORK APPLIED TO LIVE CELL IMAGING UNCOVERS A FIRST-ORDER PHASE TRANSITION BETWEEN MORPHOL OGY-BASED CELL STATES. Erin Angelini , Rebecca Zaunbrecher, Ellen Adams, Tiffany Barszczewski, Antoine Borensztejn, Julie Dixon, Renske Dupar, Jacqueline Edmonds, Maxwell Hedayati, Caroline Hookway, Chantelle Leveille, Jacob McCarley, Benji Morris, Gouthamrajan Nada rajan, Serge Parent, Emmanuel Sanchez, John Paul Thottam, Jessica Yu,. Allen Institute for Cell Science, Jin Wang, Gokhan Dalgin, Julie Theriot, Susanne M. Rafelski, Matheus Palhares Viana

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