BPS2026 Program Book

Platform Membrane Protein Folding and Structure 1:00 pm - 3:00 pm, Room 204/205/206

2024-Plat 1:15 pm MOLECULAR MAPPING OF TAU INTERACTIONS WITH PHOSPHOPRO TEIN PHOSPHATASES (PPPS): NOVEL ROUTES TO COMBAT TAU HYPER PHOSPHORYLATION IN ALZHEIMER’S DISEASE. Sachin S. Katti , Karina Shirakawa, Rachel Godek, Tvesha Parikh, Rebecca Page, Wolfgang Peti 2025-Plat 1:30 pm HIGHLY COOPERATIVE INTERACTION BETWEEN CYTOSKELETAL ADAP TOR KANK1 AND HUB PROTEIN LC8 FORMS DYNAMIC HINGED RODS SUGGESTING A STRUCTURAL ROLE FOR LC8 IN CYTOSKELETAL ASSEM BLY. Douglas R. Walker , Aidan Estelle, York-Christoph Ammon, Yujuan Song, Qianru H. Lv, Patrick N. Reardon, Muneyoshi Ichikawa, Anna Akhmanova, Elisar J. Barbar 2026-Plat 1:45 pm AMYLOID FIBRIL OF CHCHD10 AND CHCHD2 LINKED TO NEURODEGEN ERATION. Guohua Lv, Nicole Sayles, Yun Huang, Chiara Mancinelli, Kevin McAvoy, Neil Shneider, Giovanni Manfredi, Hibiki Kawamata, David Eliezer 2027-Plat 2:00 pm LIGHT-ACTIVATED TRANSBILAYER COUPLING OF PROTEIN CLUSTERS AT THE LIVING CELL MEMBRANE. Yohan Lee , Jerry Cabriales, Liping Wang, Eileen Lafer, Jeanne Stachowiak 2028-Plat 2:15 pm REGULATION AND INHIBITION OF TAU PROTEIN PHASE SEPARATION, AGGREGATION, AND TOXICITY BY A MOLECULAR CHAPERONE. Cecilia Mörman , Axel Leppert, Giusy Pizzirusso, Zihan Zheng, Xun Sun, Rakesh Kumar, Henrik Biverstal, Michael Landreh, Jan Johansson, Luis Enrique Arroyo-Garcia, Jinghui Luo, Gefei Chen, Axel Abelein 2029-Plat 2:30 pm STRUCTURAL HETEROGENEITY IN HEALTH AND MUTATED INTRINSI CALLY DISORDERED PROTEINS. Roy Beck 2030-FlashTalk 2:45 pm CANCELED 2031-FlashTalk 2:50 pm FUNCTIONAL CHARACTERIZATION OF DE NOVO , PRIMORDIAL-LIKE PRO TEINS. Peter J. Winslow , Samuel Erickson, Burckhard Seelig 2032-FlashTalk 2:55 pm HDX-MS AND CRYO-EM TO PROBE NFKB AND RPS3 INTERACTIONS. Anthony Y. Cai , Elizabeth A. Komives Platform Co-Chairs Priyanka Bajaj, University of California, San Francisco, USA Jonathan Rocheleau, University of Toronto, Canada 642-Pos 1:00 PM PROTEIN CORONA FORMED ON LIPID NANOPARTICLES COMPROMISES DELIVERY EFFICIENCY OF MRNA CARGO. Elizabeth Voke, Mariah L. Arral, Henry J. Squire, Teng-Jui Lin, Lining Zheng , Roxana Coreas, Alison Lui, Anthony T. Iavarone, Rebecca L. Pinals, Kathryn A. Whitehead, Markita P. Landry Bioengineering and Biosensors 1:00 pm - 3:00 pm, Room 209/210/211

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Co-Chairs Moritz Kretzschmar, Lawrence Berkeley National Laboratory Molecular Biophysics, USA Sarah McGuinness, University of Illinois at Chicago, USA 2013-Plat 1:00 pm CRYO-ET IDENTIFIES CLAUDIN-15-DEPENDENT TIGHT JUNCTION PORES. Evgeniya Demchenko, Sarah McGuinness , Ye Li, Shaun Wood, Victoria Pappas, Jotham Austin, Le Shen, Fatemeh Khalili-Araghi, Christopher Weber 2014-Plat 1:15 pm Travel Award Winner STRUCTURAL AND FUNCTIONAL CHARACTERISATION OF THE HUMAN VITAMIN C TRANPORTER 2 (HSVCT2). Lok I Chan , Bernadette Byrne 2015-Plat 1:30 pm Travel Award Winner VASORIN MODULATES LIGAND-DEPENDENT ASSEMBLY OF TGFΒ RECEP TOR COMPLEXES IN LIVE CELLS. Prince Ozioma Emmanuel , Adam W. Smith 2016-Plat 1:45 pm Travel Award Winner DIMENSIONALITY REDUCTION AND CLUSTERING IDENTIFY GPCR MI CROSWITCHES. Jingjing Ji , Edward R. Lyman 2017-Plat 2:00 pm STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF PROMISCU OUS SCORPION TOXINS OSK1 AND HELATX1 ON MUSCLE-TYPE NACHR. Lottie R. Steward , Kevin Ember, Victoria Kiss, Myeong Seon Lee, John Mayer, Michael H.B. Stowell 2018-Plat 2:15 pm LIPID AND DOMAIN INTERACTIONS DRIVE DISTINCT ACTIVATION PATH WAYS IN EPHA1 VS. EPHA2. Amita R. Sahoo , Matthias Buck 2019-Plat 2:30 pm Travel Award Winner TIME-RESOLVED XFEL STRUCTURES OF THE INTERMEDIATES OF THE ULTRA-FAST LIGHT REACTION OF PHOTOSYSTEM I. Moritz Kretzschmar 2020-FlashTalk 2:45 pm CCDC32 COLLABORATES WITH THE MEMBRANE TO ASSEMBLE THE AP-2 CLATHRIN ADAPTOR COMPLEX. Dillon Sloan , Ariel Matthews, Haruaki Yanagisawa, Tanita Tedamrongwanish, Kevin Cannon, Jake Simmons, Garrett Chappell, Nathan Nicely, Rebecca B. Berlow, Masahide Kikkawa, Richard Baker 2021-FlashTalk 2:50 pm STRUCTURAL DETERMINATION OF THE ELEVATOR-TYPE MOVEMENT OF ZIP PROTEINS. Nirsanka Roy , Lynn Goss Schrag, Petra Fromme 2022-FlashTalk 2:55 pm CELL-FREE SYNTHESIS AND SMALP SOLUBILIZATION FOR FUNCTIONAL ANALYSIS OF MEMBRANE PROTEINS. Shakiba Nikfarjam , Gregory Bude, Claire Robertson, Wei He, Matthew A. Coleman Platform Intrinsically Disordered Proteins II 1:00 pm - 3:00 pm, Room 207/208 Co-Chairs David Eliezer, Weill Cornell Medicine - Cornell University, USA Cecilia Mörman, Karolinska Institutet, Sweden 2023-Plat 1:00 pm DIFFERENTIAL CONFORMATIONAL EXPANSION OF NUP98-HOXA9 ONCOPROTEIN FROM NANO ASSEMBLIES TO MACROPHASES. Rodrigo F. Dillenburg , Hao Ruan, Elnaz Hosseini, Sina Wittmann, Martin Girard, Edward A. Lemke

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