BPS2026 Program Book

133-Symp 5:35 pm THE INS AND OUTS OF THE SLC13 DI-/TRICARBOXYLATE TRANSPORTERS. Da-Neng Wang , Ruben Gonzalez, Joseph Mindell, Christopher Mulligan, Emad Tajkhorshid Symposium Calcium Signaling: New Views on a Classic 4:00 pm - 6:00 pm, Room 303/304 Chair Martin Falcke, Max Delbrück Center for Molecular Medicine, Germany 134-Symp 4:00 pm NEWS FROM THE CALCIUM SIGNALLING MACHINE ROOM - BUILDING DATA-DRIVEN MODELS OF THE INOSITOL-TRISPHOSPHATE RECEPTOR (IPR) FROM SINGLE CHANNEL DATA. Ivo Siekmann 135-Symp 4:25 pm DECODING CALCIUM SIGNALS - SYNAPTOTAGMIN ISOFORMS AND DY NAMICS OF NEUROTRANSMITTER RELEASE. Shyam S. Krishnakumar 136-Symp 4:50 pm REGULATION OF INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS: CON TROLLING CA 2+ SIGNALS IN TIME AND SPACE. David I. Yule 137-SympSelect 5:15 pm Travel Award Winner CALCIUM CHANNEL AND TRANSPORTER TARGETED MODULATORS IDENTIFIED BY HIGH-THROUGHPUT SCREENING. Samantha L. Yuen, Jonathan C. Solberg, Andrew R. Thompson, Bengt Svensson, Donald M. Bers, David D. Thomas, Robyn T. Rebbeck 138-Symp 5:35 pm THE INFORMATION IN IP3-INDUCED CALCIUM SPIKE SEQUENCES. Martin Falcke Platform Condensates from Biophysics to Disease I 4:00 pm - 6:00 pm, Room 201/202/203 Co-Chairs A PROTEIN-DNA SURFACE HYDROGEL MECHANICALLY REINFORCES THE CELL NUCLEUS AND PROTECTS THE GENOME. Ramesh Adakkattil , Pranay Mandal, Yahor Savich, Valentin Ruffine, Mareike Jordan, Henrik Dahl Pinholt, Elisabeth Fischer-Friedrich, Frank Julicher, Stephan W. Grill, Alexander von Appen 140-Plat 4:15 pm MECHANOCHEMICAL FEEDBACK BETWEEN CONFINEMENT AND ACTIN CROSSLINKING DRIVES THE SHAPE DYNAMICS OF LIQUID-LIKE DROP LETS. Daniel Mansour , Domo Jordan, Caleb Walker, Aravind Chan drasekaran, Christopher T. Lee, Kristin Graham, Jeanne C. Stachowiak, Padmini Rangamani 141-Plat 4:30 pm HIGH-RESOLUTION QUANTIFICATION OF G3BP1 CONDENSATE AGE ING DYNAMICS AND ITS MODULATION BY RNA AND CAPRIN1. Anurag Singh , Bhargavi Gindra, Tharun Selvam Mahendran, Priya R. Banerjee 1582-Pos 4:45 pm PRINCIPLES OF CLIENT ENRICHMENT THROUGH SCAFFOLD-CLIENT IN TERACTIONS IN BIOMOLECULAR CONDENSATES. Aishani Ghosal, Lindsay Case, Trevor GrandPre Pin Yu Chew, University of Cambridge, United Kingdom Timothy Eisen, University of California, Berkeley, USA 139-Plat 4:00 pm

143-Plat 5:00 pm MOLECULAR DETERMINANTS OF MATERIAL PROPERTIES IN BIOMOLEC ULAR CONDENSATES. Pin Yu Chew , Maria Julia Maristany, Jan Huertas Martin, Rosana Collepardo-Guevara 144-Plat 5:15 pm PRE-ASSEMBLY OF A PARTIAL SIGNALING UNIT PRIMES T-CELL RECEP TOR SIGNAL TRANSDUCTION. Timothy J. Eisen , Saehyun Choi, Jay T. Groves 145-Plat 5:30 pm BIOPHYSICAL CHARACTERIZATION OF SARS-COV-2 NONSTRUCTURAL PROTEIN NSP8 CONDENSATES. Sharique Khan , Wellington C. Leite, Jen nifer Warnock, Youngchang Kim, Hugh M. O’Neill 146-FlashTalk 5:45 pm Travel Award Winner BIOMOLECULAR CONDENSATES DICTATE THE FOLDING LANDSCAPE OF PROTEINS. Nathaniel Hess , Jerelle A. Joseph 147-FlashTalk 5:50 pm MATERIAL PROPERTIES OF BIOMOLECULAR CONDENSATES: NEW TOOLS AND NEW INSIGHTS. Wayne Yang 148-FlashTalk 5:55 pm FLUORESCENT PROTEIN DIMER-BASED BIOSENSOR FOR QUANTITATIVE HYDROPHOBICITY MAPPING OF BIOMOLECULAR CONDENSATES IN LIVE CELLS. Alejandro SanchezPedreno Jimenez , Daniel Yan, Ziying Xu, Nicolas Lea, Lindsay Case, Youngchan Kim, Yun Chen Platform CLPA AND CLPAP CATALYZED UNFOLDING AND TRANSLOCATION ARE DIFFERENTIALLY COUPLED TO ATP BINDING. Liana Islam , Jaskamaljot Kaur Banwait, Aaron L. Lucius 150-Plat 4:15 pm DESIGN & CHARACTERIZATION OF DE NOVO PEPTIDE INHIBITORS AGAINST AN EBOLA VP35 IID CRYPTIC POCKET. Mark B. Bray , Prajna Mishra, Shahlo Solieva, Devin Kelly, Claire H. Woodward, Jonah Park, Gregory Bowman 151-Plat 4:30 pm COMPARING DOMAIN-DOMAIN COUPLED MOTIONS IN BHLH-PAS TRANSCRIPTION FACTOR COMPLEXES. Karthik Sudarsanam, Ashutosh Srivastava, Sandhya P. Tiwari 152-Plat 4:45 pm TIME-RESOLVED X-RAY SCATTERING EXPLORES ULTRAFAST STRUCTURAL CHANGES OF VISUAL RHODOPSIN. C. Swathi K. Menon, Thomas D. Grant, Suchithranga M.D.C. Perera, Leslie A. Salas-Estrada, Andrey V. Struts, Konstantinos K. Karpos, Udeep Chawla, Steven D.E. Fried, Nipuna Weerasinghe, Domingo Meza, Derek Mendez, Alan Grossfield, Petra Fromme, Richard A. Kirian, Michael F. Brown 153-Plat 5:00 pm INTERPLAY OF PROTEIN DYNAMICS AND ELECTROSTATIC PRE-ORGANI ZATION IN MOLECULAR MECHANISM OF BIOLOGICAL COPPER TRAF FICKING. Avisek Das 154-Plat 5:15 pm PHYSICS INTEGRATED MACHINE LEARNING MODELS UNCOVER PRINCIPLES OF ALLOSTERIC REGULATION IN DIVERSE FUNCTIONAL OUTCOMES. Ngoc Huynh , I. Can (John) Kazan, Jin Lu, Bethany Kolbaba Kartchner, Jeremy H. Mills, S. Banu Ozkan Protein Dynamics and Allostery 4:00 pm - 6:00 pm, Room 204/205/206 Co-Chairs Eva Gerber.University of California, Berkeley, USA Sandhya P. Tiwari, Osaka University, Japan 149-Plat 4:00 pm

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