BPS2026 Program Book

Protein Structure and Conformation I (Boards B1 - B24)

202-Pos Board B14 STUDY OF NON-NEUTRALIZING ANTI-TRANSFERRIN RECEPTOR 1 ANTI BODIES. Aldo J. Munoz , Chantal de la Cruz, Donovan Southall, Jose A. Rodriguez 203-Pos Board B15 Travel Award Winner STRUCTURAL INSIGHTS INTO INTEGRIN CONFORMATIONAL DYNAMICS UNDERLYING LEUKOCYTE ROLLING AND ADHESION. Uriel López-Sán chez , Joon Lee, Shubham Kesarwani, Alan Brown, Timothy A. Springer 204-Pos Board B16 CRYO-EM STRUCTURES OF FILAMENTS FROM THE BRAINS OF INDIVIDU ALS WITH VARIANTS G51D AND H50Q IN A-SYNUCLEIN. Yang Yang 205-Pos Board B17 TARGETING THE SKP1-SKP2 INTERACTION INTERFACE WITH PEPTIDE BASED INHIBITOR: UNDERSTANDING THE CONFORMATIONAL IMPLI CATIONS OF PROTEIN-PEPTIDE BINDING. Simran Tolani , NItesh Mani Tripathi, Debarghya Mitra, Himanshu Antil, Sushil Kumar, Anupam Bandyopadhyay, Ashutosh Kumar 206-Pos Board B18 Travel Award Winner STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF A STAND ALONE HOMODIMERIC NON-RIBOSOMAL PEPTIDE SYNTHETASE FROM GUT BACTERIA. Jitendra Singh , Thomas D. Grant, Andrew Gulick 207-Pos Board B19 STRUCTURAL MECHANISM FOR SIGNAL RESET OF PROTEIN KINASE A BY PHOSPHODIESTERASES. Varun Venkatakrishnan , Jean-Paul Armache, Ganesh S. Anand 208-Pos Board B20 STRUCTURAL AND BIOCHEMICAL ANALYSIS OF RETROVIRAL INTEGRA TION UNVEILS CROSS-NUCLEOSOME INTERACTIONS DURING VIRAL DNA INSERTION. Andres A. Rivero Gamez , Zelin Shan, Tao Jing, Gen navieve Gray, Hyejeong Shin, Andrew Routh, Dmitry Lyumkis 209-Pos Board B21 BIOACTIVE LIPID-MEDIATED STRUCTURAL AND FUNCTIONAL REGULA TION OF THE ESSENTIAL HUMAN POTASSIUM CHANNEL KIR7.1. Qingwei Niu 210-Pos Board B22 ACCURATE PREDICTION OF CANCER DRUG RESISTANT VARIANTS USING MOLECULAR SIMULATION, MACHINE LEARNING AND NETWORK MOD ELING. Longsheng Xie, Christopher Lockhart, Dmitri K. Klimov, Mohsin S. Jafri 211-Pos Board B23 IN VITRO RECONSTITUTION OF THE C. ELEGANS SYNAPTONEMAL COM PLEX. Brenda I. Cesar , Divya Yadav, Stephen D. Fried, Yumi Kim 212-Pos Board B24 POTTS MODEL ANALYSIS OF MUTATION EFFECTS ON PROTEIN STABILITY, COOPERATIVITY, AND DRUG RESISTANCE. Kisan Khatri , Allan Haldane, Ronald M. Levy Protein-Small Molecule Interaction I (Boards B25 - B52) 213-Pos Board B25 Travel Award Winner A SYSTEMATIC FRAMEWORK FOR PEPTIDE-BASED INHIBITION OF SHP2 PROTEIN-PROTEIN INTERACTIONS. Chiara Innamorati , Alessandro Stro faldi, Daniela Roversi, Luca Mignini, Claudia Storti, Luca Pannone, Sim one Martinelli, Elisabetta Flex, Paolo Calligari, Barbara Biondi, Cristina Peggion, Fernando Formaggio, Marco Tartaglia, Gianfranco Bocchinfuso, Lorenzo Stella

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189-Pos Board B1 SISTERS, NOT TWINS: UNIQUE REGULATORY MECHANISMS IN P-REX RHOGEFS INVESTIGATED USING INTEGRATIVE STRUCTURAL BIOL OGY. Lauren K. Anderson , Jennifer Cash 190-Pos Board B2 STRUCTURAL ANALYSES OF GLYCOLYTIC ENZYMES FROM TRYPANO SOMA CRUZI . Kenneth Austin , Graham Chakafana 191-Pos Board B3 BIOPHYSICAL CHARACTERISATION OF INTERACTION OF HEMOGLOBIN HEMOGLOBIN RECEPTOR COMPLEX OF LEISHMANIA . Aditi Gaur , Shashank Deep, Amitabha Mukhopadhyay 192-Pos Board B4 STRUCTURAL STUDIES OF THE OUTER SURFACE PROTEIN A (OSPA) MEMBRANE LIPOPROTEIN FROM THE LYME DISEASE AGENT BORRELIA BURGDORFERI. Najin Kim , Petra Fromme 193-Pos Board B5 Travel Award Winner STRUCTURAL OPTIMIZATION AND STABILITY ENHANCEMENT OF NTL9 THROUGH COMPUTATIONAL MODELING AND EXPERIMENTAL ANALY SIS. Bahar Ghazi Esfahani , Jean-Marc Lanchy, Mike T. Rothfuss, Bruce E. Bowler 194-Pos Board B6 CHARACTERIZING HSV-2 GH/GL BOUND BY CHL37 FAB. Hunter Russell , Gonzalo L. Gonzalez-Del Pino, Ekaterina Heldwein 195-Pos Board B7 UNSTRUCTURED REGIONS TUNE ASSEMBLY AND ELECTRON FLOW IN THE ASSIMILATORY SULFITE REDUCTASE. Fozieh Ahmadizadeh , Thais Pedrete, Nidhi Walia, Thomas Windisch, Christian Bleiholder, Elizabeth Board B8 STRUCTURAL INSIGHTS INTO THE RUBISCO-RUBISCO ACTIVASE COM PLEX IN HIGHER-ORDER PLANTS. Kira DeVore , Kazi Waheeda, Isabella Breen, Alexander Carsten, Rebekka Wachter, Po-Lin Chiu 197-Pos Board B9 EVALUATING MULTI-STATE ACCURACY OF AI PROTEIN STRUCTURE PRE DICTORS. Muhui Ye , James C. Gumbart 198-Pos Board B10 Travel Award Winner STRUCTURAL AND FUNCTIONAL ANALYSIS OF DOLUTEGRAVIR RESIS TANCE IN THE R263K/M50I/S119R INTEGRASE MUTANT. Jocelyn G. Olvera , Indrani Choudhuri, Tao Jing, Avik Biswas, Leonardo Andrade, Yuta Hikichi, Eric Freed, Dmitry Lyumkis 199-Pos Board B11 DEFINING AMYLOID STRUCTURE AND REGIONAL DISTRIBUTION IN A HOMOZYGOUS APOE3 CHRISTCHURCH VARIANT OF ALZHEIMER’S DISEASE. Tiara V. Hinton , Yang Yang 200-Pos Board B12 STRUCTURAL INSIGHTS INTO GERMLINE ANTIBODY INTERMEDIATES GUIDE HIV-1 IMMUNOGEN DESIGN. Okikiola Morenike Olajide , Josh James Carter, Erica Yu Lee, Teresia Chen, Israel Ramos, Jennie Phung, Michael Eso, Christopher O. Barnes 201-Pos Board B13 USING GENETIC EXPANSION AND FLUORESCENCE MICROSCOPY TO DEFINE HOST-PATHOGEN INTERACTIONS. Julnar Alazzam , Nesreen Ela thram, Sophie F. Young, Francesca M. Marassi, Galia T. Debelouchina Stroupe 196-Pos

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