BPS2026 Program Book

320-Pos Board B132 HIGHLY COOPERATIVE INTERACTION BETWEEN CYTOSKELETAL ADAP TOR KANK1 AND HUB PROTEIN LC8 FORMS DYNAMIC HINGED RODS SUGGESTING A STRUCTURAL ROLE FOR LC8 IN CYTOSKELETAL ASSEM BLY. Douglas R. Walker , Aidan Estelle, York-Christoph Ammon, Yujuan Song, Qianru H. Lv, Patrick N. Reardon, Muneyoshi Ichikawa, Anna Akhmanova, Elisar J. Barbar Condensates: Physical Properties and Modeling I (Boards B133 - B160) 321-Pos Board B133 IS LIQUID-LIQUID PHASE SEPARATION OF MORPHOGENS BICOID AND ZELDA CONSISTENT WITH THEIR ROLE AS TRANSCRIPTIONAL REGULA TORS? Cécile Fradin , Alex Verbeem, Lydia Hodgins, Linshan Li, Lili Zhang 322-Pos Board B134 A SINGLE MOLECULE VIEW OF PROTEIN RECRUITMENT TO TRANSCRIP TION CONDENSATES. Jan-Hendrik Spille 323-Pos Board B135 Travel Award Winner AN ELECTROSTATIC REPULSION MODEL OF CENTROMERE ORGANISA TION. Maria Julia Maristany , Lifeng Chen, Caelan Bell, Jan Huertas Martin, Huabin Zhou, Jose Ignacio Perez-Lopez, Jorge R. Espinosa, Sy Redding, Rosana Collepardo-Guevara, Michael K. Rosen, Daniel Gerlich 324-Pos Board B136 COARSE-GRAINED SIMULATIONS FOR PHYSICAL CHARACTERIZATION OF BIOMOLECULAR CONDENSATES. Ayoung Jeong 325-Pos Board B137 CONFORMATIONAL SWITCHING IN RNASE E REGULATES RNA BINDING SELECTIVITY AND BR-BODY PHASE SEPARATION. Kathryn G. Dzurik , Wade E. Schnorr, Dylan T. Tomares, W. Seth Childers 326-Pos Board B138 MOLECULAR DYNAMICS SIMULATIONS ELUCIDATE THE BIOPHYSICAL MECHANISMS OF TRANSBILAYER CONDENSATE COUPLING. Ketsia Zinga , Yohan Lee, Jeanne C. Stachowiak, Pengyu Ren 327-Pos Board B139 RNA COLLAPSE AND CONDENSATE FORMATION TUNED BY TEMPERA TURE AND COUNTERIONS. Heyang Zhang , Hung T. Nguyen 328-Pos Board B140 Travel Award Winner SICM AS A NOVEL TOOL: FROM SINGLE-PROTEIN DETECTION TO MATE RIAL PROPERTIES OF BIOMOLECULAR CONDENSATES. Helena Miljkovic , Wayne Yang, Georg Fantner, Aleksandra Radenovic 329-Pos Board B141 CLUSTERING BEHAVIOR OF HRD OF CYCLIN T1 AND CTD OF RNA POLY MERASE II. Jacob R. Oakden , Bercem Dutagaci 330-Pos Board B142 ATOMISTIC MECHANISM OF TDP-43 CONDENSATE REGULATED BY HIGHLY-CHARGED PROTEINS. Cheng Tan , Jaewoon Jung, Yuji Sugita 331-Pos Board B143 POLYMER CONFORMATIONAL ENTROPY AS DRIVER OF COMPLEX COAC ERVATION. Tommaso Inzani , Giovanni Nava, Marco Buscaglia, Andrea Soranno, Alessandro Gori, Greta Bergamaschi, Samir Suweis, Amos Maritan, Tommaso Bellini 332-Pos Board B144 CONDENSATE-DRIVEN CHROMATIN ORGANIZATION VIA ELASTOCAP ILLARY INTERACTIONS. Hongbo Zhao , Amy R. Strom, Jorine Eeftens, Mikko Haataja, Andrej Kosmrlj, Clifford P. Brangwynne

333-Pos Travel Award Winner DEVELOPMENT OF A MULTISCALE FRAMEWORK FOR ENGINEERING PROTEIN CONDENSATES AS MICROREACTORS. Virginia Q. Jiang , Ka-hei Siu, Archontoula Giannakopoulou, José Avalos, Jerelle A. Joseph 334-Pos Board B146 DECIPHERING THE POLYAMPHOLYTE DRIVEN PHASE BEHAVIOR OF IM30. Tika Ram Bhandari 335-Pos Board B147 HETEROGENEOUS AGING OF RNA CONDENSATES. Dibyajyoti Mohanta , Hung T. Nguyen 336-Pos Board B148 UNCOVERING THE DOMAINS OF PERICENTRIN THAT MIGHT ENABLE ITS PHASE-SEPARATION PROPENSITY. Dominique Ramirez , Michael R. Shirts, Loren E. Hough 337-Pos Board B149 INFERRING THE SURFACE PROPERTIES OF PROTEIN CLUSTERS THAT PRECEDE LLPS FROM THEIR SIZE DISTRIBUTIONS. Gonen Golani , Samuel Safran 338-Pos Board B150 MATERIAL PROPERTIES OF BIOMOLECULAR CONDENSATES: NEW TOOLS AND NEW INSIGHTS. Wayne Yang 339-Pos Board B151 ROLES OF HISTONE CHAPERONE NAP1 AND HISTONE ACETYLATION IN REGULATING PHASE-SEPARATION OF NUCLEOSOME ARRAYS. Jia Gao 340-Pos Board B152 NUCLEATION KINETICS REVEALS A DISTINCT BIOLOGICAL FUNCTION SPACE OF BIOMOLECULAR CONDENSATES. Leif-Thore Deck , Sandra Navarro Pacheco, Hannes Ausserwöger, Daan Frenkel, Nadia A. Erkamp, Tuomas P.J. Knowles 341-Pos Board B153 Travel Award Winner BIOMOLECULAR CONDENSATES DICTATE THE FOLDING LANDSCAPE OF PROTEINS. Nathaniel Hess , Jerelle A. Joseph 342-Pos Board B154 MOLECULAR DETERMINANTS OF MATERIAL PROPERTIES IN BIOMOLEC ULAR CONDENSATES. Pin Yu Chew , Maria Julia Maristany, Jan Huertas Martin, Rosana Collepardo-Guevara 343-Pos Board B155 MECHANOCHEMICAL FEEDBACK BETWEEN CONFINEMENT AND ACTIN CROSSLINKING DRIVES THE SHAPE DYNAMICS OF LIQUID-LIKE DROP LETS. Daniel Mansour , Domo Jordan, Caleb Walker, Aravind Chan drasekaran, Christopher T. Lee, Kristin Graham, Jeanne C. Stachowiak, Padmini Rangamani 344-Pos Board B156 CONDENSATES PROVIDE A UNIQUE ENVIRONMENT FOR REDOX-MEDI ATED PROTEIN CROSSLINKING IN VITRO AND IN LIVE CELLS. Huan Wang , Bruna Favetta, Benjamin S. Schuster, Zheng Shi 345-Pos Board B157 A PHYSICS-BASED APPROACH TO PREDICT PHASE BEHAVIOR OF PRO TEINS UNDER HEAT STRESS. Ananya Chakravarti , Jerelle A. Joseph 346-Pos Board B158 FLUORESCENT PROTEIN DIMER-BASED BIOSENSOR FOR QUANTITATIVE HYDROPHOBICITY MAPPING OF BIOMOLECULAR CONDENSATES IN LIVE CELLS. Alejandro SanchezPedreno Jimenez , Daniel Yan, Ziying Xu, Nicolas Lea, Lindsay Case, Youngchan Kim, Yun Chen Board B145

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