BPS2026 Program Book

Biopolymers in vivo (Boards S20 – S26)

Board S31 STRUCTURAL BASIS OF THE TOK1 POTASSIUM CHANNEL FROM CAN DIDA ALBICANS Brice Durocher (1095-Pos / B269) Board S32 ISOLATING LOW EXPRESSION LEVEL INTEGRAL MEMBRANE PROTEINS IN PLASMA MEMBRANE-DERIVED VESICLES FOR STRUCTURAL STUDIES Gabriel Cuce (913-Pos / B87) Board S33 FLIPPING GATING POLARITY IN HERG BY UNCOUPLING THE S4-S5 LINKER FROM THE INNER BUNDLE GATE Zhen Tong (458-Pos / B270) Board S34 BIOPHYSICAL CHARACTERISATION OF INTERACTION OF HEMOGLOBIN HEMOGLOBIN RECEPTOR COMPLEX OF LEISHMANIA Aditi Gaur (191-Pos / B3) Board S35 THE EXTRACELLULAR TURRET IS ESSENTIAL FOR GATING IN BOTH HCN AND KV CHANNELS Kaei Ryu (501-Pos / B313) Board S36 MODULATION OF THE CARDIAC SODIUM CHANNEL NAV 1.5 BY THE SEA STATE- AND USE-DEPENDENT INHIBITION OF NA V 1.7 BY POLYSORBATE 80: A COMPARATIVE ASSESSMENT OF TRITON X-100, NP-40, AND PEG Ryeong-Eun Kim (1736-Pos / B273) Board S38 EFFECTS OF BUPROPION ON SYNAPTIC AND EXTRASYNAPTIC GABA A RE CEPTORS Lauren E. Anderson (2243-Pos / B201) Board S39 DETERMINING THE ROLE OF LIPOPOLYSACCHARIDE IN DEFINING THE BINDING SPECIFICITY OF NEISSERIAL OPACITY-ASSOCIATED PROTEINS AND HUMAN CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULES Connor M. McDermott (389-Pos / B201) Board S40 STRUCTURE-GUIDED DESIGN FOR NBCN2: ROUTES TO SELECTIVE INHI BITION Lasse M. Desdorf (1786-Pos / B323) Board S41 MOLECULAR DYNAMICS REVEAL MECHANISTIC DIVERGENCE BETWEEN THE TWO PORES OF FLUC Fernando Montalvillo (2278-Pos / B236) Board S42 DEVELOPMENT OF DIGITAL TWINS FOR L-TYPE CALCIUM CHANNEL INHIBITION Aleena Siritanapivat (1746-Pos / B283) Board S43 ELUCIDATING THE CROSS-TALK BETWEEN PHOSPHORYLATION ANDDIS EASE-CAUSING MUTATIONS IN FAST INACTIVATION OF VOLTAGE-GATED SODIUM CHANNELS Shiva Akhlaghi (1743-Pos / B280) ANEMONE PEPTIDE ANTHOPLEURIN A (APA) Gewil Daniella O. Allas (1744-Pos / B281) Board S37

F R I D A Y

S U N D A Y

Board S20 EXTRACELLULAR PROTEIN SCAFFOLDS FOR DE NOVO PEPTIDE NANOPORES TO ADVANCE AMINO ACID IDENTIFICATION Ayaka Nakada (2048-Pos / B6) Board S21 THERMAL STABILITY OF AI-DESIGNED PROTEIN CROWDERS Caroline Davis (1478-Pos / B15) Board S22 FLUORESCENCE IMAGING OF GENE LOCI IN ESCHERICHIA COLI REVEALS MARKER SIZE-DEPENDENT DYNAMICS AND SPATIALLY HETEROGENEOUS CHROMOSOME CONFINEMENT Yu-Huan Wang (987-Pos / B161) Board S23 HYPERSENSITIVE DETECTION OF BIOMOLECULES IN PHYSIOLOGICAL MEDIA BY LC-PHOTO-CIDNP-ENHANCED BENCHTOP NMR SPECTROS COPY Anubhab Halder (1204-Pos / B378) Board S24 UNCOVERING THE DOMAINS OF PERICENTRIN THAT MIGHT ENABLE ITS PHASE-SEPARATION PROPENSITY Dominique Ramirez (336-Pos / B148) Board S25 POLYMER CONFORMATIONAL ENTROPY AS DRIVER OF COMPLEX COAC ERVATION Tommaso Inzani (331-Pos / B143) Board S26 MOLECULAR DYNAMICS SIMULATIONS: INSIGHT INTO EFFECTS OF POLY MER OSMOLYTES ON MEMBRANE PROTEIN HYDRATION Lauren E. Thaller (2084-Pos / B42) Channels, Receptors, and Transporters (Boards S27 – S47) Board S27 MOLECULAR MODELING AND SIMULATIONS OF MUTANT CARDIAC SODIUM CHANNELS NAV1.5 FOR PATIENT-SPECIFIC ARRHYTHMIA TREATMENT Yen-Her Lai (1132-Pos / B306) Board S28 STRUCTURAL DYNAMICS OF THE HUMAN MU-OPIOID RECEPTOR IN A LIPID-FREE ENVIRONMENT Eugene Agyemang (2086-Pos / B44) Board S29 INTERROGATING EXTRACELLULAR UNSTRUCTURED DOMAINS OF AMPA RECEPTOR AUXILIARY PROTEINS USING FRET Jonathan J. Stallone (2246-Pos / B204) Board S30 UNRAVELLING RAPID KINETICS DRIVING HUMAN DAYLIGHT VISION Sarah Luise Schmidt (903-Pos / B77)

53