Biophysical Newsletter - March 2014

Newsletter MARCH 2014

DEADLINES

Neither Snow, Nor Ice, Nor Flight Cancellations... Could keep nearly 7,000 biophysicists from attending the BPS Annual Meeting in San Francisco, February 15-19

Thematic Meetings 2014 Modeling of Biomolecular Systems Interactions, Dynamics, and Allostery September 10–14, 2014 Istanbul, Turkey May 5 Abstract Submission June 16 Early Registration Significance of Knotted Structures for Function of Proteins and Nucleic Acids September 17–21, 2014 Warsaw, Poland May 12 Abstract Submission June 23 Early Registration Disordered Motifs and Domains in Cell Control October 11–15, 2014 Dublin, Ireland June 2 Abstract Submission July 11 Early Registration

It was another great meeting where re- searchers came to bridge the sciences to explore, understand, and solve biological problems and create new collaborations and research communities.

During heavy snowstorms in the Eastern US, San Francisco welcomed researchers from over 46 countries with blue skies and unseasonably warm and sunny weather. With over 850 poster presentations each

day, poster sessions never stopped buzz- ing. The speaker presentations in the more than 24 sympo- sia and workshops and

63 platform sessions added to the palpably electric atmosphere. Twelve subgroup pro- grams on the Saturday before the meeting's official start saw standing room only attendance.

For pictorial highlights from the Meeting, see page 6.

Society Awards Nomination Deadline: May 1

Each year, the Biophysical Society honors its members and recognizes excellence in biophysics through its Awards Program. Nominations are now being accepted for eight awards, which will be presented at

the 2015 Annual Meeting in Baltimore, Maryland, February 7–11. For more information about the Biophysical Society Awards, visit www.biophysics.org and click on Awards/Opportunities.

CONTENTS

2 4 5 6

8 9

Biophysicist in Profile Biophysical Journal

Networking Events Grants and Opps Members in the News

Biophysical Society

10 12

Public Affairs

Annual Meeting

Upcoming Events

2

2014

BIOPHYSICAL SOCIETY NEWSLETTER

MARCH

BIOPHYSICAL SOCIETY

Biophysicist in Profile DAUMANTAS MATULIS

Officers President Dorothy Beckett President-Elect Edward Egelman Past-President Francisco Bezanilla Secretary Lukas Tamm Treasurer Paul Axelsen Council Olga Boudker Taekjip Ha Samantha Harris Kalina Hristova Juliette Lecomte Amy Lee Marcia Levitus Merritt Maduke Daniel Minor, Jr. Jeanne Nerbonne Antoine van Oijen Joseph D. Puglisi Michael Pusch Bonnie Wallace David Yue Biophysical Journal Leslie Loew Editor-in-Chief

When Daumantas Matulis was a high school student in Lithuania, an intimidat- ing teacher taught him the basics of chemistry. With this knowledge, he won third place in the Lithuanian National High School Olympiad. Now, many years later, he says, “I still consider this probably my greatest achievement.” After high school, Matulis enrolled in Vilnius University, studying biochemistry. It was there that he met Rex E. Lovrien , a professor from the University of Minnesota who would become his PhD advisor. In 1990, Lovrien had decided that potential scientists in the Baltics could benefit from training in the US, so he traveled to

“ I am grateful for my years in industry, where I got not only significant experience in drug design, but also the vision that all research is for the bet- ter understanding and better application to practice. ” – Daumantas Matulis

Vilnius to instruct the science majors there on how to do so. Lovrien explained how to take the Test of English as a Foreign Language (TOEFL) and Graduate Record Examinations (GRE), and taught the students how to apply to graduate schools in the US. Matulis traveled to Moscow to take the necessary tests, and after he passed, Lovrien paid for Matulis’s flight to the US.

Matulis entered the University of Minnesota and un- dertook rotations in a protein x-ray crystallography lab and an NMR lab. “I was happy with the help from my PhD committee. I am really indebted to them,” says Matulis, “ Douglas Ohlendorf and Leonard Ban- aszak taught me crystallography; Kevin Mayo and Clare Woodward taught me protein NMR and the use of hydrogen exchange to follow the protein folding.” Matulis eventually landed in Lovrien’s lab, studying protein ligand interac- tions with the emphasis of using ligands to protect, selectively precipitate, isolate, and purify proteins. Here he learned the method most important in his career—isothermal titration calorimetry—as well as the fundamentals of biothermodynamics. “I remember Rex ringing a bell in a corridor trying to attract graduate students and postdocs to listen to weekly presentations of departmental journal club and research reviews,” Matulis recalls. Following these presentations were “interesting discussions with students who are now prominent scientists, such as Vincent J. LiCata and Hiroki Morizono ,” he says. After finishing his PhD with Lovrien, Matulis obtained a postdoctoral posi- tion in the field of DNA biophysics with Victor Bloomfield . Bloomfield’s lab was home to a diverse group of postdocs who introduced Matulis to a variety of new fields: single molecule biophysics with Mark C. Williams ; dynamic light scattering with Christoph G. Baumann , Jeffrey J. Schwinefus , Jay R. Wenner , and Siddhartha Jena ; ultrasound velocity and densitometry with Besik Kankia ; and computational biophysics with Ioulia Rouzina and Karen Tang . Being exposed to this assortment of fields served as a great learning experience for Matulis, who himself began to focus on lipid, ion, and protein binding to DNA.

Society Office Ro Kampman Executive Officer

Newsletter Alisha Yocum Monika Zakrzewska Production Laura Phelan Profile

Ellen Weiss Public Affairs

The Biophysical Society Newsletter (ISSN 0006-3495) is published twelve times per year, January- December, by the Biophysical Society, 11400 Rockville Pike, Suite 800, Rockville, Maryland 20852. Distributed to USA members and other countries at no cost. Canadian GST No. 898477062. Postmaster: Send address changes to Biophysical Society, 11400 Rockville Pike, Suite 800, Rockville, MD 20852. Copyright © 2014 by the Biophysical Society. Printed in the United States of America. All rights reserved.

3

BIOPHYSICAL SOCIETY NEWSLETTER

2014

MARCH

Following his postdoc position, Matulis found work as a research scientist with 3-Dimensional Pharmaceuticals (3-DP), a mid-sized company later acquired by Johnson & Johnson. Matulis says, “I am grateful for my years in industry, where I got not only significant experience in drug design, but also the vision that all research is for the better understanding and better application to practice.” His experience working in industry served to enrich his scientific viewpoint and repertoire, but upon re- turning to Lithuania, he also returned to academia. In his current position as Head of the Department of Biothermodynamics and Drug Design at the In- stitute of Biotechnology, Vilnius University, Matu- lis oversees about 40 researchers and students. The goal in assembling this team was to bring together scientists from a variety of fields: organic synthesis, target protein recombinant production in bacte- rial and human cells, computational molecular modeling to benefit synthesis efforts, protein- ligand binding biophysics, x-ray crystallography, pharmacy, and immunology. As Matulis had experienced in his previous positions, this variety of viewpoints and foci has led to stimulating science. He explains, “I believe that most new and exciting science is born at the interface between these fields. We have designed over 550 ligands that specifi- cally bind carbonic anhydrase (CA), a well-studied enzyme that has twelve isoforms in humans and has been implicated in various diseases such as can- cer, glaucoma, epilepsy, and obesity, to mention a few.” The laboratory hopes eventually to publish a database of the x-ray crystal structures that are correlated to the measurements of intrinsic binding thermodynamics to all twelve CA isoforms. In addition to his science, Matulis offers the lab his talent at bringing out the best in those around him. Joana Gylytė , his student of four years, says, “Dr. Matulis is a true leader who takes care of every group member and inspires others to do their best. He is eager to share his experience and encourages everybody to realize their ideas.” For his part, Matulis finds seeing his students’ progress to be one of the most rewarding aspects of his work as a biophysicist. While Matulis’s research and mentoring are fulfilling to him, his career certainly has presented

him with challenges as well. His time training and working in the US was valuable, but he explains, “Going to the USA was easier than to return and produce decent science that could be of interest in the USA.” Additionally, maintaining a professional network with scientists in the US has been difficult after returning to Lithuania. “The Biophysical Society takes a very special place in my life,” Matulis says, “It is one of the main remaining connections with the US scientists.” Matulis has been working at establishing connections closer to home, too. In 2012, he hosted a successful networking event with the help of a Biophysical Society mini-grant. Over thirty biophysicists working in Lithuania met to discuss their research and the future of the biophysics community within the country, and in the context of the larger European community. Matulis’s scientific activities outside of the lab have not gone unnoticed—or unappreciated. Osvaldas Rukšėnas , Dean of the Faculty of Natural Sciences at Vilnius University, says of Matulis, “What I like in him is that in addi- tion to being a high level scientist, he is very active in science policy activities. He doesn’t close himself in the laboratory.” When he is not working on his research or on science policy, Matulis enjoys exercise (especially field tennis); reading about politics, history, and geography; and traveling. More important than these pursuits is the time he spends with his family, which includes his four children, and his wife, Jurgita Matulienė , who received her PhD in cell biology from the University of Min- nesota in 2003, and returned to Lithuania with Matulis to conduct her research. For those considering careers in biophysics, Matulis would encourage them to continue on their path, wherever they may be coming from: “I believe that there could be very many different paths to biophysics, and therefore there could be no best advice. However, I feel that the overall field of deep molecular understanding of cellular phenomena where weak non-covalent forces are involved will give us great challenges for many years….the choice to be a researcher in biophysics is the right one.”

Daumantas Matulis with Rex Lovrien (left) at the confluence of Mississippi and Ohio rivers after a Gibbs Conference in Carbondale, Illinois, in 2001.

Matulis on vacation with his family (wife, Jurgita Matulien and their four children, from oldest: Eimantas, Renata, Vaigintas, and the little Tautvydas) at Druskininkai Resort in Lithuania in 2012.

4

BIOPHYSICAL SOCIETY NEWSLETTER

2014

MARCH

Biophysical Journal Corner

New & Notables

Know the Editors

Charles Wolgemuth University of Connecticut Health Center Editor for Systems Biophysics Section

The following is a list of New &Notable articles re- cently published in BJ . Visit www.biophysj.org to read these articles. SAXS/SANS probe of intermolecular interactions in concentrated protein solutions by Huan-Xiang Zhou and Osman Bilsel , which highlights the papers: Minimal Effects of Macromolecular Crowding on an Intrinsically Disordered Protein: A Small-Angle Neutron Scattering Study and Self Crowding of Globular Proteins Studied by Small-Angle X-Ray Scattering, both by David Goldberg and Brian Argyle . Star Light, Star Bright, First Molecule I See Tonight by Christopher Yip , which highlights the papers: Eliminat- ing unwanted far-field excitation in objective-type TIRF. Part I. Identifying sources of non-evanescent excitation light by Martin Oheim , Maia Brunstein , Maxime Teremetz , Karine Hérault and Christophe Tourain , and Eliminating unwanted far-field excitation in objective- type TIRF. Part II. Combined evanescent-wave ex- citation and supercritical-angle fluorescence detection improves optical sectioning by Martin Oheim , Maia Brunstein and Karine Hérault . Does Ephaptic Coupling Contribute to Propagation in Cardiac Tissue? by Bradley Roth , which highlights the paper: Microdomain Effects on Transverse Cardiac Propagation by James Keener and Joyce Lin . Mechanically guided cell migration: less of a stretch than ever by Guy Genin and Elliot Ellson , which highlights the paper: Mechanical Boundary Conditions Bias Fibroblast Invasion in a Collagen-Fibrin Wound Model by Jeffrey Holmes and Andrew Rouillard . The Berg-Purcell Limit Revisited by Sean Sun, which highlights the paper: The Berg-Purcell limit revisited by Pieter Rein ten Wolde , Kazunari Kaizu , Wiet De Ronde , Joris Paijmans , Koichi Takahashi and Filipe Tostevin .

Charles Wolgemuth

Q: What is your area of research? I am broadly interested in understanding mechanisms in biology, and it is likely my background in physics that caused me to gravitate specifically toward addressing questions about how cells move. Cellular movements play a substantial role in many areas of biology, including multi-cellularity, development, and disease. For example, many bacterial infections require that bacteria migrate to a hospitable place in the host. Our white blood cells then must be able to move to these locations to eradicate the bacteria. My group focuses on understanding how the bacterium that causes Lyme disease is able to penetrate through dense polymeric and cell-filled environments, such as the extra-cellular matrix or blood vessels, in order to infect the skin and penetrate into joints and the central nervous system of mammalian hosts. We are also investigating the biophysics of multi- cellular movements during wound healing, cancer metastasis and tissue structure formation. My scientific attitude is founded in doubt; I do not trust my own thinking. Therefore, if I am unable to frame a mechanism within a mathematical model that can quantitatively explain experiments, then I do not understand the biology. Our research approach uses mathematical models to develop hypotheses, and then test these hypotheses using quantitative experiments, typically involving imaging to watch cell movements in real-time. This combination of modeling and experiment has enabled us to develop a model that can explain the dynamics of rash forma- tion during early Lyme disease. We plunge forward to who-knows -what next.

BJ in the Press

The article Spatio- temporal Evolution of Erythema Migrans, the Hallmark Rash of Lyme Disease by Charles Wolgemuth and Dhruv Vig , is sub- ject of a recent press release issued by Cell Press. See the Febru- ary 4 issue of Biophysical Journal . High Resolution: In Vivo Optical Imaging This latest in a series of webinars pre- sented by Biophysical Journal is available online at www.biophysj.org Moderated by Dave Piston of the Vanderbilt School of Medicine

5

BIOPHYSICAL SOCIETY NEWSLETTER

2014

MARCH

Public Affairs

success rates for R01 grants have declined, the average size of research project grants (RPG) has decreased, and the total number of RPG applications received by NIH decreased as well. The NIH also saw a decline in incoming applications for the first time since 2009. Read the full post at: http://nexus.od.nih.gov/ all/2014/01/10/fy2013-by-the-numbers/. The NIH Data Book may be found at: http://report.nih.gov/nihdatabook/index.aspx 2014 Appropriations Trend Upwards Three months after the start of the FY 2014 bud- get, Congressional Appropriators finally agreed on how the discretionary funds should be divided. On January 13, they released the 1,500 page appropriations package, called the Consolidated Appropriations Act for 2014. The bill includes a partial elimination of sequester cuts. For science funding, it was a move in the right direction, albeit a small move for NIH. While the NSF, DOE, NIST, and NASA received increases over their 2013 spending levels ranging from 4.2%-11.2%, NIH received a 3.5% increase over its 2013 level. In constant dollars, the NIH budget is approxi- mately 15% lower than in FY2004. For a general agency breakdown, see chart below. President Obama is scheduled to release his FY2015 budget on March 5.

NIH Workforce Diversity Chief Named

NIH appointed Hannah Valentine to the posi- tion of NIH Chief Officer for Scientific Workforce Diversity on January 30. According to the NIH press release, Valentine “will lead the NIH’s efforts to diversify the biomedical research workforce by developing a vision and comprehensive strategy to expand recruitment and retention, and promote inclusiveness and equity throughout the biomedical research enterprise.” Valentine joins the NIH from Stanford University Medical Center, where she served as the Senior Associate Dean for Diversity and Leadership and Professor of Cardiovascular Medicine. NIH Data Book Shows FY 2013 Decline The NIH Data Book, which shows basic summary statistics on extramural grants, grant applications, NIH supported trainees and fellows, the US bio- medical workforce, and more, has been updated with FY 2013 data. In her January 10 blog, NIH Deputy Director for Extramural Research Sally Rocker reported that

FY 2014 Appropriations for Science Agencies (in billions)

Agency

FY 2012

FY 2013 with sequester cuts

FY 2014

NIH

30.046

28,604

29.63

NSF

5.614

6,884

7.172

DOE Office of Science

4.463

4,621

5.071

NASA Science Office

5.399

4,78

5.15

NIST Science & Tech Labs

5.55

5.80

6.51

6

BIOPHYSICAL SOCIETY NEWSLETTER

2014

MARCH

58 TH ANNUAL MEETING FEBRUARY 15–19, 2014 | SAN FRANCISCO, CALIFORNIA

Symposia & Workshops

President's Day President's Day occurred during the Meeting. Honoring its own Mount Rushmore of Presidents, (left to right) are Dorothy Beckett, Richard Aldrich, Edward Egelman, and Francisco Beza- nilla.

The 2014 Meeting featured over 100 sessions, including 24 symposia, five workshops, and 63 platform sessions highlighting the latest research topics and biophysical techniques.

National Lecture Carlos Bustamante presented A Journey Through Cellular Processes: One Molecule at a Time at the National Lecture on Monday, February 17.

Career Programs The BPS Meeting included over 20 career- and education-related sessions for attendees at all career levels.

iPad and Kindle Paperwhite Winners

Weiyan Li, Rhode Island Hospital, won the Kindle Paperwhite during the Meet the Speakers/Meet the Editors event.

Autoosa Salari, University of Missouri, won the exhibitor iPad raffle.

7

2014

BIOPHYSICAL SOCIETY NEWSLETTER

MARCH

B R I D G I N G T H E S C I E N C E S T O E X P L O R E B I O L O G Y

Poster Presentations

Over 4,500 abstracts were submitted for the Meeting, with over 500 platform pre- sentations selected from among submitted abstracts. Nearly 900 posters were presented each day in the exhibit hall.

Image Contest The Biophysical Society’s fourth annual Image Contest, sponsored by Asylum Research, received over 50 submissions. The 12 finalist entries were displayed at the An- nual Meeting, where attendees voted on their top two images. The prizes were sponsored by Chroma Technology. Congratula- tions to the 1 sts , 2 nd , and 3 rd place winners. For the description of the images, visit www.biophysics.org

1 st Place Flow Visualization at the Surface of a Lipid Vesicle Model Mattieu Chavent

2 nd Place Dynein Motors along Microtubule Tracks Graham Johnson

3 rd Place Ice Crystals Growth in Microfluidics Ran Drori

1 st Place Image Contest Winner, Mattieu Chavent.

Exhibits With a record number of new companies dem-

onstrating their products, attendees had the opportunity to see the latest lab equipment and scientific publications, and to explore new technologies in the exhibit hall during the meeting.

8

BIOPHYSICAL SOCIETY NEWSLETTER

2014

MARCH

58 TH ANNUAL MEETING FEBRUARY 15–19, 2014 | SAN FRANCISCO, CALIFORNIA

2014 SRAA Winners

Alex Holehouse , Washington University in St. Louis; Parsing the Contributions of Poly- peptide Backbones and Sidechains to Denatur- ation in Concentrated Aqueous Solutions of Urea and Guanidinium Chloride . Mechanobiology Hema Chandra Kotamarthi , Tata Institute of Fundamental Research; Experimental and Simulation Studies on the Mechanical Properties of Sumo Proteins . Membrane Biophysics Donald Chang , Columbia University; Cardio- myocyte Endpoints Distinguish Non-Canonical Regulation of the RGK GTPses Rad and Rem . Membrane Structure & Assembly Jonathan Zerweck , Karlsruhe Institute of Technology; Structure Activity Relationship for a Synergistic Pair of Antimicrobial Peptides from the Magainin Family . Melinda Diver , Memorial Sloan-Kettering Cancer Center; Mapping the Substrate Binding Sites of the Integral Membrane Methyltransferase ICMT by Mutational Analysis . Molecular Biophysics Zackary Scholl , Duke University; N-Terminal Domain of Luciferase Controls Misfolding Avoidance . Motility Darshan Trivedi , Pennsylvania State Univer- sity; Dynamics of the Lever-Arm Swing in Myosin V Nanoscale Biophysics Karin Kornmueller , Medical University of Graz; Self-Assembly of an Amphiphilic Designer- Peptide into Double Helical Superstructures . Jaime Ortega Arroyo , University of Oxford; Label-Free, All-Optical Detection, Imaging and Nanometric Tracking of Single Proteins . Permeation & Transport Felix Hohendanner , Rush University Chicago; IP3 Receptor Mediated Ca Release in Atrial Cells from Normal and Failing Hearts .

A Few Words from Annual Meeting Attendees

Biophysical Society Annual Meeting is an opportunity to rein- force what I know, to learn a lot of new things relevant to my own research, and also to learn about cool things outside my field. – Archana Madhavan, BPS Blogger This is a wonderful opportunity to gain a better understand- ing for why so many scientists pursue bio- physics research and how I can play a role within the scientific community in the near future. – Joshua Yoon, BPS Blogger

The 15 winners of the annual Student Re- search Achievement Awards (SRAA) were recognized at the 58 th Annual Meeting Awards Ceremony on February 17. These students were selected by judges from the Society’s subgroups for their outstanding presentations during the poster competition. One hundred and thirty-nine students participated in the competition. The winners are: Bioenergetics Soroosh Solhjoo , Johns Hopkins University; Inhbition of Mitochondrial N a+ /Ca 2+ Exchanger Suppresses Ischemia/Reperfusion-induced Reentry in Monolayers of Cardiomyocytes. Biological Fluorescence Katherina Hemmen , Heinrich-Heine University; Deciphering Folding Pathways of Phage T4 Lysozyme: Influence of Multiple Con- formations . Biopolymers in vivo Shasha Chong , Harvard University; Mechanism of Transcriptional Bursting in Bacteria . Exocytosis & Endocytosis Czuee Morey , University of Lausanne; Interac- tion of Munc18c with Syntaxin4 and the Role of Munc18c in Exocytosis . Intrinsically Disordered Proteins Kiersten Ruff , Washington University in St. Louis; Role of Intrinsic Helicity within N- Terminal Flanking Sequences on Huntingtin Aggregation Mechanisms .

9

2014

MARCH

BIOPHYSICAL SOCIETY NEWSLETTER

Networking Events

Grants and Opportunities

Office of Science and Technology Policy Internship Program—Summer 2014 Objective: To provide a unique opportunity to work closely with senior White House officials and science and technology (S&T) policy analysts in OSTP's topic-based divisions (Division intern- ship), or on OSTP's legal team (Legal internship) Who Can Apply: Students who are US citizens enrolled, at least half-time, in an accredited col- lege or university during the period of volunteer service. Students in undergraduate, graduate, and professional programs in all fields are encouraged to apply. Application Deadline: March 7

Since 2011, BPS members have hosted networking events that have brought together local scientists to discuss various topics in biophysics. This year, BPS has already committed to sponsoring four network- ing events:

Networking Events in the US

October 18, 2014 University of Wisconsin La Crosse, WI

March 29, 2014 Milwaukee School

of Engineering Milwaukee, WI

Website: http://www.whitehouse.gov/ administration/eop/ostp/about/student

Instrument Development for Biological Research (IDBR)

Objective: To support the development, produc- tion, and distribution of novel instrumentation that addresses demonstrated needs in biologi- cal research in areas supported by NSF Biology programs Who Can Apply: Universities and Colleges, non-profit and non-academic organizations Application Deadline: July 25, 2014 Website: http://www.nsf.gov/pubs/2013 nsf13561/nsf13561.htm

May 12, 2014 University of Kentucky Lexington, KY

Networking Events Outside the US

June 6, 2014 The Pasteur Institute Paris, France

Networking Event Proposals Do you have an idea for a networking event and want to host one in your area? BPS will be accepting networking event proposals until April 15. If selected, you can receive up to $500 through the Membership Committee’s mini-grant program to host your event. For more information about networking events and proposal requirements, visit the Membership section of the Society website at www.biophysics.org.

Suggest a Student or Postdoc to Spotlight

Do you have a spotlight-worthy student or postdoc in your lab? Let us know. Send his/her name to society@biophysics.org so that they can be featured in the newsletter.

10

BIOPHYSICAL SOCIETY NEWSLETTER

2014

MARCH

Members in the News

18 TH INTERNATIONAL BIOPHYSICS CONGRESS August 3–7, 2014 | Brisbane, Australia •••

Mary Kraft , University of Illinois, Urbana Champaign, and Society member since 2004, has been awarded the Walter Shaw Young Investigator Award in Lipid Research by the American Society for Biochemistry and Molecular Biology (ASBMB). Lila Gierasch , University of Massachusetts and Society member since 1981, was selected to receive the Mildred Cohn Award in Biological Chemistry by the American Society for Biochemistry and Molecular Biology (ASBMB).

Abstract Submission and Early Registration Deadline: May 2, 2014 •••

Organized by: Australian Society for Biophysics (ASB) and

the International Union of Pure and Applied Biophysics (IUPAB)

For more information, go to: www.iupab2014.org

Introducing Digital ClampOne ™ from NEUROSCIENCE TOOLS “THE GAME CHANGER” (OHFWURSK\VLRORJ\&ODPSLQJ$PSOLÀHU Booth #803 at BPS 2014

A TRULY ALL DIGITAL PLATFORM FOR CONDUCTING ION CHANNEL EXPERIMENTS

Digital Clamp One™ with Dual Headstages and Laptop. Available with 4 Headstages. Developed with SBIR NS48682 from NINDS

NeuroscienceTools.com | (630) 964-0501 | Charles.Scouten@neurosciencetools.com

Biophysical Journal Call for Papers

Special Issue: Focus on Quantitative Cell Biology

For publication December 2, 2014, Volume 107, Number 11

Biophysical Journal will publish a special issue of the Journal with a focus on Quantitative Cell Biology. The Journal welcomes submissions that report on studies of biological molecules and structures with a focus on mechanisms at the cellular level using the

concepts and methods of physics, chemistry, mathematics, engineering, and computational science. Studies should further our understanding of the interactions between the various systems of a cell as well as how these

interactions are regulated. The journal aims to publish the highest quality work and articles should have sufficient importance to be of general interest to biophysicists, regardless of their research specialty.

Deadline for submission: July 1, 2014

s 0LEASE INCLUDE A COVER LETTER STATING THAT YOU WOULD LIKE TO BE PART OF THE SPECIAL ISSUE ON 1UANTITATIVE #ELL "IOLOGY s 3ELECT h3PECIAL )SSUE &OCUS ON 1UANTITATIVE #ELL "IOLOGYv WHEN UPLOADING YOUR SUBMISSION s )NSTRUCTIONS FOR AUTHORS CAN BE FOUND AT HTTP DOWNLOAD CELL COM

IMAGES EDIMAGES "IOPHYS )NSTRUCTIONS?TO?!UTHORS PDF s 1UESTIONS CAN BE DIRECTED TO THE BJ %DITORIAL /FlCE AT "* BIOPHYSICS ORG OR

*OURNAL PUBLICATION FEES WILL APPLY

PUBLISHED BY

Biophysical Society

For more information, go to www.biophysj.org

Presorted First Class Mail U.S. Postage PAID Claysburg, PA Permit #6

Biophysical Society

11400 Rockville Pike, Suite 800 Rockville, Maryland 20852

UPCOMING EVENTS

BIOPHYSICAL SOCIETY NEWSLETTER MARCH 2014

May

June

July

August August 3–7, 2014 18 th International Biophysics Congress Brisbane, Queensland http://www.iupab2014.org/ August 24–29 ICMRBS 2014 — XXVI International Conference for Magnetic Resonance in Biological Systems Dallas, Texas http://www2.biochem.wisc.edu/ icmrbs/?p=210%20

May 4–9, 2014 Electronic Processes in Organic Materials Lucca, Italy http://www.grc.org/programs. aspx?year=2014&program= elecproc May 27–30, 2014 The Second International Conference on Radiation and Dosimetry in Various Fields of Research (RAD 2014) Nis, Serbia http://www.rad2014.elfak.rs/ welcome.php

July 5–6, 2014 Endothelial Cell Phenotypes in Health & Disease (GRS) Girona–Costa Brava, Spain http://www.grc.org/programs. aspx?year=2014&program=grs_ endo July 12–17, 2014 European Bioenergetics Conference (EBEC 2014) Lisbon, Portugal http://www.ebec2014.org/

June 13–15, 2014 The Third International Conference on Analytical and Nanoanalytical Methods for Biomedical and Environmental Sciences Brasov, Romania http://icanmbes.unitbv.ro/ index.html June 18–20, 2014 Algebraic and Discrete Biological Models for Undergraduate Courses, a NIMBioS Tutorial Knoxville, Tennessee http://nimbios.org/tutorials/ TT_mathbio

Please visit www.biophysics.org for a complete list of upcoming events.