Biophysical Society 2020 Annual Meeting

Protein Structure and Conformation II (Boards B1 - B21) 933-Pos Board B1 EXPERIMENTAL TEST OF ENSEMBLE-INDUCED EPISTASIS IN MACROMOL- ECULES. Anneliese J. Morrison , Michael J. Harms 934-Pos Board B2 PP2A PHOSPHATASE ACTIVATOR (PTPA): KEY TO THE MASTER REGULATOR IS CRUCIAL FOR SURVIVAL OF ENTAMOEBA HISTOLYTICA ; STRUCTURAL AND FUNCTIONAL ELUCIDATION. Priya Tomar , Gourinath Samudrala 935-Pos Board B3 EFFECT OF BILAYER THICKNESS ON MECHANICAL ACTIVATION OF THE ANGIOTENSIN II TYPE 1 RECEPTOR. Bharat Poudel , Rajitha R. Tatikonda, Juan M. Vanegas 936-Pos Board B4 SINGLE-MOLECULE FLUORESCENCE SPECTROSCOPY OF NON-LIPIDATED FORMS OF APOLIPOPROTEIN E. Melissa D. Stuchell-Brereton , Logan Calderone, Berevan Baban, Jasmine Cubuk, Greg DeKoster, Carl Frieden, Andrea Soranno 937-Pos Board B5 ACTIVATION OF A PHOTOENZYME RESULTS IN MODIFIED STRUCTURE AND DYNAMICS. Andreas M. Stadler , Judith Schneidewind, Michaela Zamponi, Esther Knieps-Grünhagen, Samira Gholami, Ulrich Schwane- berg, Ivan Rivalta, Marco Garavelli, Mehdi Davari, Karl-Erich Jaeger, Frank Krause, Marco Bocola, Ulrich Krauss 938-Pos Board B6 IN-CELL STRUCTURE DETERMINATION OF AN ANTIMICROBIAL PEPTIDE BY DNP SOLID-STATE NMR. Shiying Zhu , Frances Separovic, Marc Antoine Sani 939-Pos Board B7 PRINCIPLES OF ATP AND GTP SELECTIVITY IN NMP KINASES. Per Rogne, Elisabet Sauer-Eriksson, Uwe Sauer, Christian Hedberg, Magnus Wolf- Watz 940-Pos Board B8 FLANKING DISORDER AFFECTS THE CONFORMATIONAL ENSEMBLE AND DYNAMICS OF A SMALL FOLDED HUB DOMAIN. Lasse Staby , Micha Kunze, Katherine R. Kemplen, Karen Skriver, Birthe B. Kragelund 941-Pos Board B9 THE VARIABLE DOMAIN FROM THE MITOCHONDRIAL FISSION MECHA- NOENZYME DRP1 PROMOTES LIQUID-LIQUID PHASE SEPARATION.  Blake Hill , Ammon E. Posey, Mehran Bagheri, Megan C. Harwig, Nolan W. Kennedy, Vincent J. Hilser, James L. Harden 942-Pos Board B10 STRUCTURE AND FUNCTION OF A SOLUBLE PRECURSOR OF HUMAN PULMONARY SURFACTANT PROTEIN SP-B. Alejandro Alonso , Barbara Olmeda, Olga Cañadas, Jesus Perez-Gil 943-Pos Board B11 DISSECTING CONTRIBUTIONS TO EFFICIENT CATALYSIS IN THE TRNA MODIFYING ENZYME TILS. Ferdiemar C. Guinto , Rebecca W. Alexander, Freddie R. Salsbury 944-Pos Board B12 INVESTIGATION OF DRUG RESISTANCE MECHANISMS FOR ANTIANDRO- GEN PROSTATE CANCER DRUG ENZALUTAMIDE USING MOLECULAR DYNAMICS SIMULATIONS. Behzad Aslani Avilaq, Sefer Baday

945-Pos Board B13 CHARACTERIZATION OF AIF5A PROTEIN: A MULTIFUNCTIONAL TRANSLA- TION FACTOR IN THE HYPERTHERMOPHILIC ARCHAEON S. SOLFATARI- CUS . Alice Romagnoli , Flavia Bassani, Paolo Moretti, Francesco Spinozzi, Udo Bläsi, Daniele Di Marino, Anna La Teana 946-Pos Board B14 Travel Awardee ELECTROSTATICS AND THE CONTROL OF ENDOGENOUS HEME LIGATION BY PH IN A HEMOGLOBIN.  Jaime E. Martinez , Laia Julió Plana, Jamie L. Schlessman, Darío A. Estrin, Luciana Capece, Juliette T. Lecomte 947-Pos Board B15 HIGH-THROUGHPUT MUTATIONAL SCREEN IDENTIFIES PHENOTYPICALLY RELEVANT CATEGORIES OF MUTATIONS IN FUMARATE HYDRATASE. David Shorthouse , Michael W.J. Hall, Benjamin A. Hall 948-Pos Board B16 THE DETERMINANTS FOR LIGAND BINDING OF THE DOMESTICATED RET- ROVIRAL PROTEIN ARC. Christian Parsbæk Pedersen , Lau Dalby Nielsen, Simon Erlendsson, Kaare Teilum 949-Pos Board B17 ALTERATION OF TBID-INDUCED APOPTOTIC BAX PORATION IN MITO- CHONDRIAL MEMBRANES BY MUTATIONS AND SMALL MOLECULES. Fei Qi 950-Pos Board B18 MECHANISMS OF CARDIAC ARRHYTHMIAS AND SUDDEN CARDIAC DEATH IN HUMAN CALMODULINOPATHY. Ryan L. Woltz , Hannah A. Led- ford, Padmini Sirish, Duncan Muir, Wen Smith, Xiao-Dong Zhang, Vladimir Yarov-Yarovoy, Nipavan Chiamvimonvat 951-Pos Board B19 MOLECULAR BASIS FOR HEME EXTRACTION OF THE ANTIMICROBIAL TARGET ISDH FROM STAPHYLOCOCCUS AUREUS FROM HUMAN HEMO- GLOBIN. Sandra Valenciano Bellido , Vu T. Nhuan, Makoto Nakakido, Jose M. M. Caaveiro, Kouhei Tsumoto 952-Pos Board B20 DARWINIAN SHIFT: A GENERAL APPROACH FOR ESTABLISHING EVIDENCE AND MECHANISM OF NATURAL SELECTION. Michael W. Hall, David Short- house, Philip H. Jones, Benjamin A. Hall 953-Pos Board B21 ROSSMANN-LIKE PROTEINS FUNCTION AND EVOLUTION ANALYSIS OF A FIFTH OF THE PROTEIN WORLD. Kirill E. Medvedev , Lisa N. Kinch, Nick V. Grishin Protein Stability, Folding, and Chaperones I (Boards B22 - B40) 954-Pos Board B22 ENERGETIC DEPENDENCIES AMONG DOMAINS DICTATE FOLDING MECHANISM IN A COMPLEX PROTEIN. Kaixian Liu, Xiuqi Chen, Christian M. Kaiser 955-Pos Board B23 ZEBRAFISH OOCYTES AS A TOOL FOR EUKARYOTIC IN-CELL NMR.  Joseph F. Thole , Samantha S. Stadmiller, Gary J. Pielak 956-Pos Board B24 Travel Awardee POLYETHYLENE GLYCOL SIZE AND PROTEIN STABILITY. Claire J. Stewart , Shannon L. Speer, Francis J. Lauzier, Daniel Harries, Gary J. Pielak 957-Pos Board B25 UNDERSTANDING THE UNDERLYING PRINCIPLES BEHIND CONFOR- MATIONAL SWITCH OF CHEMOKINES. Prabir Khatua , Alan Ray, Ulrich Hansmann

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