Biophysical Society 2020 Annual Meeting

1091-Pos Board B159 MACROMOLECULAR CONDENSATION FACILITATES LARGELY 3D MRNA TARGET SEARCH BY MICRORNAS. Hui Li, Ameya P. Jalihal , Sethu Pitchiaya, Nils G. Walter 1092-Pos Board B160 RNA-PROTEIN PHASE SEPARATION IN CANCER: INVESTIGATING HUMAN SATELLITE II RNA STRUCTURE AND FUNCTION.  Jack D. Rubien , Bede Portz, Liliya Yatsunyk, Dawn Carone 1093-Pos Board B161 PRP22 REMODELING OF PRE-MRNA DURING THE P-TO-ILS SPLICEOSOME TRANSITION. Elizabeth C. Duran , Nils G. Walter 1094-Pos Board B162 CRISPR-CAS12A NUCLEASES BIND FLEXIBLE DNA DUPLEXES WITHOUT RNA-DNA COMPLEMENTARITY. Wei Jiang, Jaideep Singh, Aleique Allen, Yue Li, Venkatesan Kathiresan, Omair Qureshi, Narin Tangprasertchai, Xiaojun Zhang, Hari Priya Parameshwaran, Rakhi Rajan, Peter Z. Qin 1095-Pos Board B163 DIRECT OBSERVATION OF CRISPR-CAS12 CONFORMATIONAL SAMPLING BY SM FRET AND CRYO EM REVEALS HOW CONFORMATIONAL ACTIVA- TION PROMOTES CATALYSIS AND RESETTING OF THE ENDONUCLEASE ACTIVITY. Stefano Stella, Pablo Mesa, Johannes Thomsen, Bijoya Paul, Pablo Alcon, Simon B. Jensen, Matias E. Moses, Guillermo Montoya, Nikos S. Hatzakis 1096-Pos Board B164 A CATALYTICALLY ENHANCED TYPE II-C CAS9 THROUGH DIRECTED PRO- TIEN EVOLUTION. Travis H. Hand, Mitchell O. Roth , Chardasia L. Smith, Emily Shiel, Hong Li 1097-Pos Board B165 MAPPING THE BOUNDARY OF DNA UNWINDING IN CRISPR-CAS9 TARGET RECOGNITION. Yukang Liu , Yue Li, Narin Tangprasertchai, Peter Z. Qin 1098-Pos Board B166 REAL-TIME OBSERVATION OF DNA CLEAVAGE BY CRISPR-CAS9 ENDONU- CLEASE USING PYRENE MOLECULE AS A SENSITIVE PROBE FOR DETECT- ING SUB-NM STRUCTURAL CHANGE.  Jinho Park 1099-Pos Board B167 CHARACTERIZING THE PROTEIN/RNA INTERACTIONS IN THE INITIAL EVENTS OF HIV-1 ASSEMBLY. Emily Cannistraci , Ugonna Mbaekwe, Alexis Waller, Sapna Bassapa, Nansen Kuo, Aaron Kidane, Mitali Sarkar, Ridhi Chaudhary, Hana Flores, Pengfei Ding, Michael F. Summers 1100-Pos Board B168 POLARIZATION MOLECULAR DYNAMICS OF AN RNA DUPLEX:G-QUADRU- PLEX JUNCTION IN COMPLEX WITH THE FRAGILE X MENTAL RETARDA- TION PROTEIN. Brian D. Ratnasinghe , Alexa M. Salsbury, Justin A. Lemkul 1101-Pos Board B169 ENERGY LANDSCAPE OF THE COMPLEX BETWEEN THE RGG BOX DOMAIN OF FRAGILE-X MENTAL RETARDATION PROTEIN AND AN RNA G-QUADRU- PLEX. Kendy A. Pellegrene , Mihaela-Rita Mihailescu, Jeffrey D. Evanseck 1102-Pos Board B170 COTRANSCRIPTIONAL MOONLIGHTING OF RSMC AS AN RNA CHAPER- ONE PROTEIN. Keshav G C , Prabesh Gyawali, Hamza Balci, Sanjaya Abeysi- rigunawardena 1103-Pos Board B171 HISTONE TAILS DYNAMICS IN CANONICAL AND SUBNUCLEOSOMAL PARTICLES INVESTIGATED WITH MOLECULAR DYNAMICS SIMULA- TIONS. Lokesh Baweja , Emma A. Morrison, Catherine A. Musselman, Jeffery M. Wereszczynski

1104-Pos Board B172 UNRAVELING THE HISTONE REPLACEMENT PATHWAY IN SPERM.  Ruth O. Mosunmade , Yuxing Ma, Ashley Carter 1105-Pos Board B173 RESOLVING THE DYNAMICS OF THE DOUBLE STRANDED RNA BINDING PROTEIN TRBP. Oliver Stach , Sebastian L. König, Andrea Holla, Flurin Stur- zenegger, Sebastian Doden, Daniel Nettels, Benjamin Schuler 1106-Pos Board B174 INVESTIGATING NUCLEOSOME STABILITY VIA FRET. Loiselle Gonzalez Baez , Caitlin Aguirre, Elizabeth Jamieson, Megan E. Nunez 1107-Pos Board B175 COARSE-GRAINED MODELS FOR COMPLEX COACERVATION IN CHROMA- TIN. Kathryn M. Lebold 1108-Pos Board B176 REPACKAGING DNA: FROM NUCLEOSOME CORE PARTICLES TO PROT- AMINE LOOPS. Yuxing Ma , Obinna Ukogu, Ashley Carter 1109-Pos Board B177 PROTAMINE FOLDS DNA INTO A FLOWER SHAPE BEFORE FORMING TO- ROIDS. Ryan B. McMillan , Hilary A. Bediako, Luka Matej Devenica, Yuxing E. Ma, Ashley R. Carter Membrane Physical Chemistry II (Boards B178 - B201) 1110-Pos Board B178 MEMBRANES WITH DECREASED DEFORMABILITY TO STUDY THE KINET- ICS OF FUSION INTERMEDIATES. Ana Villamil , Peter Kasson 1111-Pos Board B179 ALPHA-HELICAL MEMBRANE PROTEIN FOLDING IN “MIXED” AND “IDEAL” BICELLES. Nicole Swope , Soenke Seifert, Linda M. Columbus 1112-Pos Board B180 ORDER PARAMETER ANALYSIS OF LIPIDS ORGANIZATION IN THE PRES- ENCE OF ATP. Azam Shafieenezhad , Andres T. Cavazos, Abhinav Ramku- mar, Stephen R. Wassall, Horia I. Petrache 1113-Pos Board B181 NANODOMAINS PERSIST TO MUCH HIGHER TEMPERATURES THAN LARGE SCALE PHASE SEPARATION IN GIANT PLASMA MEMBRANE VESICLES AND CAN RESPOND DIFFERENTLY TO ALTERATIONS OF PLASMA MEMBRANE LIPID COMPOSITION. Guangtao Li, Shinako Kakuda, Bingchen Li , Qing Wang, Erwin London 1114-Pos Board B182 A COMPARISON OF THREE FLUOROPHORES IN LANGMUIR MONOLAY- ERS. Benjamin L. Stottrup , Dametre Thunberg, Joan C. Kunz 1115-Pos Board B183 CONNECTIONS BETWEEN MACROSCOPIC WETTABILITY AND LIPID STRUCTURES ON CLAY MONTMORILLONITE.  Joshua K. Kibue , Brenda L. Kessenich, Elias Nakouzi, James J. De Yoreo 1116-Pos Board B184 PLASMA MEMBRANE PERMEABILITY IS ALTERED IN LIVING MAMMALIAN CELLS BY PERTURBATIONS OF LIPID MEMBRANE COMPOSITION.  Jessica L. Symons , Kandice R. Levental, Ilya Levental 1117-Pos Board B185 EUTECTIC EXPLAINS FUNCTION OF THERMORESPONSIVE LIPOSOMES - RESOLVING THE LYSOLIPID PARADOX. Daniel Eckhardt, Johannes Schnur, Jessica Steigenberger, Louma Kalie, Ulrich Massing, Georg Pabst, Heiko H. Heerklotz

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