Biophysical Society 2020 Annual Meeting

1147-Pos Travel Awardee QUANTITATIVE ASSESSMENT OF THE DYNAMIC MODIFICATION OF LIPID- DNA PROBES ON LIVE CELL MEMBRANES. Yousef Bagheri , Mingxu You Membrane Active Peptides and Toxins I (Boards B216 - B240) 1148-Pos Board B216 CROWDING ALTERS THE KINETICS OF POLYPEPTIDE-PROTEIN NANO- PORE INTERACTION. Motahareh Ghahari Larimi , Lauren A. Mayse, Liviu Movileanu 1149-Pos Board B217 CHARACTERIZATION OF MEMBRANE PORES FORMED BY CATIONIC AM- PHIPATHIC Α-HELICAL ANTIMICROBIAL PEPTIDES. Erik Strandberg , David Bentz, Parvesh Wadhwani, Jochen Bürck, Anne S. Ulrich 1150-Pos Board B218 MEMBRANE PORE FORMATION BY MELITTIN DERIVATIVES. Aliasghar Sepehri , Leo PeBenito, Almudena Pino-Angeles, Themis Lazaridis 1151-Pos Board B219 Travel Awardee ANTIMICROBIAL PEPTIDES IMPAIR BACTERIA CELL STRUCTURES WITHIN SECONDS. Enrico F. Semeraro , Johannes Mandl, Lisa Marx, Theyencheri Narayanan, Sylvain Prévost, Helmut Bergler, Karl Lohner, Georg Pabst 1152-Pos Board B220 EFFECTS OF MEMBRANE POTENTIAL ON THE ENTRY OF CELL-PENETRAT- ING PEPTIDES TRANSPORTAN 10 INTO SINGLE VESICLES.  Md. Mizanur R. Moghal , Md. Zahidul Islam, Farzana Hossain, Samiron Kumar Saha, Masahito Yamazaki 1153-Pos Board B221 LIPID COMPOSITION, PROTONATION, AND DIVALENT CATIONS AS MODULATORS OF PROTEIN-MEMBRANE INTERACTIONS. Victor Vasquez Montes , Alexey Ladokhin 1154-Pos Board B222 EFFECTS OF COLD ATMOSPHERIC PLASMAS ON MEMBRANES.  Joseph H. Lorent , Min Xie, Fabrice Gilissen, J. Antoinette Killian 1155-Pos Board B223 THE ANTIMICROBIAL PEPTIDE POLYMYXIN B1 ENCOUNTERS MANY MOLECULAR OBSTACLES IN THE PERIPLASM EN ROUTE TO THE INNER MEMBRANE OF E. COLI . Syma Khalid , Conrado Pedebos 1156-Pos Board B224 DEPROTONATION OF C-TERMINAL ACIDIC RESIDUES HOLDS THE KEY TO THE EXIT PATHWAY OF PHLIP. Violeta Burns , Blake Mertz 1157-Pos Board B225 DISCOVERING NOVEL HEMOCOMPATIBLE ANTIMICROBIAL PEPTIDES US- ING HIGH-THROUGHPUT SCREENING AND RATIONAL VARIATION. Jenisha Ghimire , Charles G. Starr, William C. Wimley, Shantanu Guha, Joseph P. Hoffmann, Yihui Wang, Lisa A. Morici 1158-Pos Board B226 CHARACTERIZATION OF CHARGE-ZIPPER TETRAMERIC ASSEMBLY OF THE STRESS RESPONSE PEPTIDE TISB FROM E. COLI IN MODEL MEM- BRANES. Parvesh Wadhwani , Benjamin Zimpfer, Violetta Schneider, Jochen Burck, Johannes Reichert, Erik Strandberg, Stephan L. Grage, Markus Elstner, Tomás Kubar, Anne S. Ulrich 1159-Pos Board B227 RHOMBOHEDRAL TRAP FOR STUDYING MOLECULAR OLIGOMERIZATION IN MEMBRANES: APPLICATION TO DAPTOMYCIN. Ming-Tao Lee , Wei-Chin Hung, Huey W. Huang Board B215

1160-Pos Board B228 INDUCED-FIT PATHWAY ACCELERATED BINDING OF AGITOXIN-2 TO A K + CHANNEL IMAGED BY HS-AFM. Ayumi Sumino , Takashi Sumikama, Taka- yuki Uchihashi, Shigetoshi Oiki 1161-Pos Board B229 NMR STRUCTURAL STUDIES AND ANTIBACTERIAL KILLING MECHANISMS OF ANTIMICROBIAL PEPTIDES WITH HIGHER ACTIVITY. Yongae Kim 1162-Pos Board B230 Travel Awardee INSIGHTS INTO THE EFFECT OF THE MEMBRANE ENVIRONMENT ON THE THREE-DIMENSIONAL STRUCTURE-FUNCTION RELATIONSHIP OF ANTIMICROBIAL PEPTIDES. William J. Zamora , Silvana De Souza, Frances Separovic, Fco. Javier Luque 1163-Pos Board B231 DIVALENT CATIONS AND LIPID COMPOSITION MODULATE MEMBRANE INSERTION AND CANCER-TARGETING ACTION OF PHLIP. Victor Vasquez Montes , Janessa S. Gerhart, Damien Thevenin, Alexey Ladokhin 1164-Pos Board B232 SELECTIVE CARGO RELEASE FROM LIPID VESICLES BY A SYNTHETICALLY EVOLVED, NON-TOXIC, VESICLE-PERMEABILIZING PEPTIDE. Leisheng Sun , Kalina Hristova, WilliamWimley 1165-Pos Board B233 MEMBRANE PERFORATION BY THE PORE-FORMING TOXIN PNEUMO- LYSIN. Martin Vögele , Ramachandra M. Bhaskara, Estefania Mulvihill, Katharina van Pee, Özkan Yildiz, Werner Kühlbrandt, Daniel J. Müller, Gerhard Hummer 1166-Pos Board B234 CATIONIC ANTIMICROBIAL PEPTIDES HAVE REDUCED BINDING TO MPRF- MODIFIED MEMBRANES. Patrick W. Simcock , Mark S. Sansom, Phillip J. Stansfeld, Maike Bublitz, Jason Crain, Maxim G. Ryadnov, Flaviu Cipcigan 1167-Pos Board B235 Travel Awardee MEMBRANE POTENTIAL IS VITAL FOR RAPID PERMEABILIZATION OF PLASMA MEMBRANES AND LIPID BILAYERS BY THE ANTIMICROBIAL PEPTIDE LACTOFERRICIN B. Farzana Hossain , Md. Mizanur Moghal, Md. Zahidul Islam, Md. Moniruzzaman, Masahito Yamazaki 1168-Pos Board B236 EFFECTS OF POLYUNSATURATED FATTY ACIDS AND METALLATION ON THE ANTIMICROBIAL ACTIVITY AND MEMBRANE-DISRUPTIVE PROPERTIES OF HOST-DEFENSE METALLOPEPTIDE PISCIDIN 1. Myriam Cotten , Steven Paredes, Sarah Kim, Alexander Greenwood, Yawei Xiong, Kalina Hristova, David Giles 1169-Pos Board B237 AMPHOTERICINB INTERACTION WITH DMPC/ERGO MIXED LIPID BILAY- ERS. Wei-Chin Hung , Chi-Jiun Hung 1170-Pos Board B238 PISCIDINS AT MEMBRANE INTERFACES: PHOSPHOLIPIDS VERSUS LPS. Hannah Cetuk , Joseph Maramba, Madolyn Britt, Robert K. Ernst, Ella Mihailescu, Myriam Cotten, Sergei I. Sukharev 1171-Pos Board B239 INCREASED POTENCY OF ANTIMICROBIAL PISCIDINS IN THE PRESENCE OF COPPER (II) CORRELATES DIRECTLY WITH INSERTION DEPTH AND ORIENTATION IN MEMBRANES. Fatih Comert , Frank Heinrich, Alexander Greenwood, Vitalii I. Silin, Myriam Cotten, Ella Mihailescu 1172-Pos Board B240 PEPTIDE-DRUG CONJUGATES ACROSS THE BLOOD-BRAIN BARRIER: USING VIRAL PROTEIN DOMAINS TO SHUTTLE SMALL DRUGS TO THE CENTRAL NERVOUS SYSTEM. Miguel A.R.B. Castanho

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