Biophysical Society 2020 Annual Meeting

1669-Plat 4:30 pm A DESIGNER FG-NUP THAT RECONSTITUTES THE SELECTIVE TRANSPORT BARRIER OF THE NUCLEAR PORE COMPLEX.  Alessio Fragasso , Henry de Vries, Eli van der Sluis, Erik Van der Giessen, Patrick R. Onck, Cees Dekker 1670-Plat 4:45 pm INSIGHTS INTO SPOP-SUBSTRATE BEHAVIOR THROUGH STUDIES OF PDX1-SPOP INTERACTIONS.  Grace A. Usher , Roman Rohac, Nafiseh Sabri, Tanja Mittag, Amie K. Boal, Scott A. Showalter 1671-Plat 5:00 pm DECIPHERING THE CONFORMATIONAL STATE OF FG-NUCLEOPORINS IN SITU .  Sofya Mikhaleva , Piau Siong Tan, Miao Yu, Edward A. Lemke 1672-Plat 5:15 pm MOLECULAR DETERMINANTS OF LARGE CARGO TRANSPORT INTO THE NUCLEUS.  Joana Caria , Giulia Paci, Tiantian Zheng, Anton Zilman, Edward A. Lemke 1673-Plat 5:30 pm SPECIFIC SEQUENCE FEATURES REGULATE THE TRANSIENT BINDING BETWEEN FG NUCLEOPORINS AND CARGO COMPLEXES. Mohaddeseh Peyro , Mohammad Mofrad 1674-Plat 5:45 pm COARSE-GRAINED MODELING OF NUCLEAR PORE COMPLEX MIMICS COMPRISING DESIGNER FG-NUCLEOPORINS.  Henry de Vries , Alessio Fragasso, Eli O. van der Sluis, Cees Dekker, Erik Van der Giessen, Patrick R. Onck Platform Membrane Active Peptides and Toxins 4:00 pm - 6:00 pm, Room 23ABC Co-Chairs Sonia Troeira Henriques, Queensland University of Technology, Australia Marc-Antoine Sani, University of Melbourne, Australia 1675-Plat 4:00 pm CHALLENGING THE CHIRALITY PARADIGM IN PEPTIDE-LIPID INTERAC- TIONS.  Sónia Troeira Henriques , Hayden Peacock, Aurélie H. Benfield, Conan K. Wang, David Craik 1676-Plat 4:15 pm MODELING NATURAL BILAYERS WITH MIXED LIPID NANODISCS FOR NA- TIVE MS. Marius Kostelic , Ciara Zak, David Jurkowitz, Michael T. Marty 1677-Plat 4:30 pm SYNERGISM BETWEEN MAGAININ 2 AND PGLA IN BACTERIAL MEM- BRANE MIMICS LEADS TO MEMBRANE FUSION AND SPONGE PHASE FORMATION.  Ivo Kabelka, Michael Pachler, Sylvain Prévost, Ilse Letofsky- Papst, Karl Lohner, Georg Pabst, Robert Vacha 1678-Plat 4:45 pm PEPTIDE KINETICS IN SYMMETRIC AND ASYMMETRIC MEMBRANE MIM- ICS OF GRAM-NEGATIVE BACTERIA.  Lisa Marx , Enrico F. Semeraro, Georg Pabst, Karl Lohner 1679-Plat 5:00 pm Travel Awardee SOLID-STATE NMR STUDY OF LIVE BACTERIA IN THE PRESENCE OF AN- TIMICROBIAL AGENTS.  Shiying Zhu, Sarah A. Overall, Vinzenz Hofferek, Frances Separovic, Marc-Antoine Sani 1680-Plat 5:15 pm SOLID-STATE NMR OF INTACT BACTERIA REVEALS THE EFFECT OF STRESS AND ANTIMICROBIAL AGENTS.  Zeineb Bouhlel, Dror E. Warschawski, Alexandre A. Arnold, Karine Lemarchand, Réjean Tremblay, Isabelle Marcotte

1681-Plat 5:30 pm THE EBOLA VIRUS Δ-PEPTIDES ARE ENTEROTOXIC VIROPORINS IN VIVO AND POTENTIALLY DRUGGABLE TARGETS.  Shantanu Guha , Lilia Melnik, Jenisha Ghimire, Allison Smither, Eric Wu, Leisheng Sun, Nathan Unger- leider, Erik Flemington, Robert F. Garry, William C. Wimley 1682-Plat 5:45 pm MUNC13 CLUSTERS CAPTURE VESICLES TO LIPID BILAYER MEMBRANE.  Feng Li , R. Venkat Kalyana Sundaram, Jeff Coleman, Shyam S. Krishnaku- mar, Frederic Pincet, James Rothman Platform Cardiac, Smooth, and Skeletal Muscle Electrophysiology and Regulation I 4:00 pm - 6:00 pm, Room 24ABC QUANTITATIVE CROSS-SPECIES PREDICTION OF Β-ADRENERGIC RESPONSE IN VENTRICULAR MYOCYTES.  Stefano Morotti , Haibo Ni, Lianguo Wang, Alex Fogli Iseppe, Donald M. Bers, Andrew G. Edwards, Crystal M. Rip- plinger, Eleonora Grandi 1684-Plat 4:15 pm HEXOSAMINE PATHWAY INDUCES CARDIAC ARRHYTHMIA VIA MODULA- TION OF SUSTAINED POTASSIUM CURRENTMODULATION OF SUSTAINED POTASSIUM CURRENT. Matthieu Douard, Fanny Vaillant, Emma Abell, Pierre Dos Santos, Fabien Brette 1685-Plat 4:30 pm Travel Awardee REGIONAL AND TEMPORAL CHANGES IN ATRIAL ELECTROPHYSIOLOGY CONTRIBUTE TO ATRIAL FIBRILLATION IN ANGIOTENSIN II INDUCED HYPERTENSION.  Hailey J. Jansen , Robert A. Rose 1686-Plat 4:45 pm HIERARCHICAL PACEMAKER CLUSTERING WITHIN THE RABBIT SINO- ATRIAL NODE IS DRIVEN BY DYNAMIC INTERACTION BETWEEN THE COMPONENTS OF THE COUPLED-CLOCK SYSTEM.  Xiaoyu Yuan, Lucas N. Ratajczyk, Francisco Alvarado, Hector H. Valdivia, Alexey V. Glukhov, Di Lang 1687-Plat 5:00 pm DYNAMIC REGULATION OF K AND CA CURRENTS IN LIPOTOXIC SUPRA- VENTRICULAR ARRHYTHMIAS.  Laura Martinez -Mateu Martinez-Mateu, Charles Leduc, Xusheng Zhang, Lisa Cole Burnett, Xiaoyun Sun, Yufeng Shen, Rudolph Leibel, Javier Saiz, Ademuyiwa S. Aromolaran 1688-Plat 5:15 pm FUNCTIONAL MICRODOMAIN OF ADENYLYL CYCLASE ISOFORM 1 CONTRIBUTES TO SINOATRIAL NODE AUTOMATICITY VIA Β-ADRENERGIC RECEPTOR PATHWAY.  Lu Ren , Phung N. Thai, Raghavender R. Gopireddy, Valeriy Timofeyev, Hannah A. Ledford, Ryan L. Woltz, Seojin Park, Claudia M. Moreno, Luis F. Santana, Alana C. Conti, Yang K. Xiang, Vladimir Yarov- Yarovoy, Ebenezer N. Yamoah, Manuel F. Navedo, Nipavan Chiamvimon- vat 1689-Plat 5:30 pm Travel Awardee ELECTRICAL REMODELLING CONTRIBUTES TO ATRIAL FIBRILLATION IN TYPE 2 DIABETES MELLITUS.  Loryn J. Bohne , Hailey J. Jansen, Motahareh Moghtadaei, Robert A. Rose 1690-Plat 5:45 pm STABILIZER CELLS: A LESS-IS-MORE GENE THERAPY STRATEGY TO PRE- VENT CARDIAC ARRHYTHMIAS. Michael B. Liu , Silvia Priori, Zhilin Qu, James N. Weiss Co-Chairs Eleonora Grandi, University of California, Davis Hailey Jansen, University of Calgary, Canada 1683-Plat 4:00 pm

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