Biophysical Society 2020 Annual Meeting

1949-Pos Board B219 CALCIUM INFLUX THROUGH PIEZO1 CHANNELS TRANSIENTLY CLUSTERS PI(4,5)P2 AND RECRUITS ACTIN POLYMERIZATION. Michael Zucker, Arnd Pralle 1950-Pos Board B220 VISCOELASTIC MECHANICAL MODELS OF THE LINC COMPLEX. Kamyar Behrouzi , Zeinab Jahed, Mohammad Mofrad 1951-Pos Board B221 STRESS FIBER CONTRACTILITY IS ESSENTIAL IN MOTOR-CLUTCH DYNAM- ICS AND CELL REMODELING UNDER CYCLIC STRETCH. Namrata Gundiah , Siddhartha Jaddivada 1952-Pos Board B222 MARGARIC ACID DECREASES SENSORY NEURONS MECHANICAL EXCIT- ABILITY BY INHIBITING PIEZO2 CHANNELS. Luis O. Romero , Julio F. Cordero-Morales, Valeria Vasquez 1953-Pos Board B223 HETEROGENEOUSLY STRAINED TISSUE COLLAGEN RESISTS COLLAGE- NASE DEGRADATION WHERE STRAINS ARE HIGH. Karanvir Saini , Manu Tewari, Sangkyun Cho, Abdelaziz Jalil, Jerome Irianto, Manasvita Vashisth, Charlotte Pfeifer, Lawrence J. Dooling, Cory Alvey, Alex Kasznel, David Chenoweth, Kazuhiro Yamamoto, Dennis E. Discher 1954-Pos Board B224 A NOVEL ROLE FOR PIEZO1 IN DIABETES-ASSOCIATED THROMBO- SIS. Wandi Zhu , Cissy Nsubuga, Shane Wright, Manu Beerens, Tuomas Kiviniemi, Vanessa Raskin, Rahul C. Deo, Calum A. MacRae 1955-Pos Board B225 CHARACTERIZATION OF KINDLIN-2 VARIANTS’ MOLECULAR BEHAVIOR UNDER APPLIED TENSION. Fayyaz R. Ahamed , Brian Jeffers, Zeinab Jahed, Mohammad Mofrad 1956-Pos Board B226 MEASURING THE EFFECT OF SUBSTRATE STIFFNESS ON CELL MEMBRANE TENSION USING OPTICAL TWEEZERS.  Jeffrey Mc Hugh , Eva Kreysing, Sarah K. Foster, Kurt Andresen, Kristian Franze, Ulrich F. Keyser Exocytosis and Endocytosis (Boards B227 - B251) 1957-Pos Board B227 CATIONIC CELL-PENETRATING PEPTIDES TRAVERSE MEMBRANES THROUGH LYSIS OR DIRECT TRANSLOCATION PATHWAYS. Jason M. War- ner, Dong An , Benjamin S. Stratton, Ben O’Shaughnessy 1958-Pos Board B228 VESICLE SHRINKING AND ENLARGEMENT: THE YIN AND YANG OF EXO- CYTOTIC CONTENT RELEASE. Wonchul Shin , Gianvito Arpino, Sathish Thiyagarajan, Rui Su, Zachary A. McDargh, Lihao Ge, Xiaoli Guo, Lisi Wei, Oleg Shupliakov, Albert J. Jin, Ben O’Shaughnessy, Ling-Gang Wu 1959-Pos Board B229 EFFECT OF SIMPLE ANESTHETICS ON SNARE FUSION PROTEINS AND ON FUSING MEMBRANES. Robert E. Coffman , Samuel W. Shumway, Andrew T. Barton, Mark T. Parsons, Austin L. Zimmerman, Ryan D. Sorensen, Dixon J. Woodbury 1960-Pos Board B230 SYNAPTIC VESICLE RELEASE PROBABILITY, KINETICS, AND CA-SENSITIV- ITY ARE REGULATED BY SNARE-PROTEINS. Zachary A. McDargh , Ben O’Shaughnessy

1961-Pos Board B231 INHIBITION OF AIRWAY EPITHELIAL SNARE/SYNAPTOTAGMIN MEDIATED MEMBRANE FUSION BY HYDROCARBON-STAPLED PEPTIDES. Ying Lai , Giorgio Fois, Manfred Frick, Burton Dickey, Axel T. Brunger 1962-Pos Board B232 A POLYBASIC PATCH ON SYNAPTOTAGMIN-1 C2A DOMAIN IS ESSENTIAL FOR EVOKED RELEASE AND DILATION OF FUSION PORES. Zhenyong Wu, Lu Ma, Jie Zhu, Nicholas Courtney, Yongli Zhang, Edwin R. Chapman, Erdem Karatekin 1963-Pos Board B233 THE SYNAPTOTAGMIN-1 ARGININE APEX BINDS TO MEMBRANES AND THE SNARE-COMPLEX, BUT ONLY TO MEMBRANES IN THE PRESENCE OF ATP/MG 2+ . Sarah B. Nyenhuis , Nakul Karandikar, Anusa Thapa, Binyong Liang, Lukas K. Tamm, David S. Cafiso 1964-Pos Board B234 IN VITRO CONFIGURATION OF MUNC13-1 BRIDGING OF PHOSPHOLIPID BILAYERS AT RESTING CONDITIONS. Kirill S. Grushin , R. Venkat Kalyana Sundaram, Kimberley Gibson, Shyam S. Krishnakumar, Charles V. Sindelar, James Rothman 1965-Pos Board B235 MUNC13-1 AND MUNC18-1 COOPERATIVELY CHAPERONE SNARE AS- SEMBLY THROUGH A TETRAMERIC COMPLEX. Yongli Zhang , Tong Shu, James Rothman 1966-Pos Board B236 MUNC13 RECRUITS SNAP25 TO FACILITATE SNARE COMPLEX ASSEMBLY.  R Venkat Kalyana Sundaram , Feng Li, Jeff Coleman, Frederic Pincet, James Rothman, Shyam S. Krishnakumar 1967-Pos Board B237 THE C2C-MCT DOMAIN OF MUNC13 IS ESSENTIAL FOR PRIMING SYN- APTIC VESICLES. Murugesh Narayanappa , Haowen Liu, Lei Li, Francesco Michelassi, Zhitao Hu, Jeremy Dittman 1968-Pos Board B238 BINDING OF COMPLEXIN TO T-SNARE COMPLEX IS MEDIATED BY SNAP25. Binyong Liang , Julian Stashower, Alex J. Kreutzberger, Volker Kiessling, Lukas K. Tamm 1969-Pos Board B239 VISUALIZING THE EFFECTS OF 3D CULTURE MATRICES ON INSULIN GRAN- ULE RELEASE IN BETA CELL PSEUDOISLETS USING LIGHT SHEET MICROS- COPY. Elizabeth D. White, Nick Bayhi , Adam G. Fine, Ahmed Selim, Noah Gamble, Daozheng Gong, Tegan Marianchuk, Andrew V. Molina, Elisabeth Rennert, Adam T. Hammond 1970-Pos Board B240 Travel Awardee PLASMA MEMBRANE ORDER REGULATES INSULIN GRANULE EXOCYTO- SIS. Chase Amos , Noah Schenk, Volker Kiessling, Alex J. Kreutzberger, Weronika Tomaka, Mounir Bendahmane, Hitomi Seki, Yosuke Niko, Andrey S. Klymchenko, Lukas K. Tamm, Arun Anantharam 1971-Pos Board B241 TWO DISTINCT POPULATIONS OF INSULIN GRANULES THAT HAVE UNIQUE PROPERTIES. Alex J. Kreutzberger , Noah Schenk, Amanda E. Ward, Catherine A. Doyle, Megan T. Harris, Binyong Liang, Arun Ananth- aram, Volker Kiessling, Lukas K. Tamm, J. David Castle 1972-Pos Board B242 SPATIOTEMPORAL ORGANIZATION OF MMP9 AND ITS EXOCYTOTIC ORGANIZING ELEMENTS IN MCF7 BREAST CANCER CELLS. Dominique C.

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Stephens 1973-Pos

Board B243 USING FLUORESCENT PROTEINS TO MONITOR GLUCAGON GRANULES IN LIVE CELLS. Alessandro Ustione , Priya Mathur, David W. Piston

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