Biophysical Society 2020 Annual Meeting

2024-Pos Board B294 STRUCTURAL BASIS OF TRPV3 ACTIVATION AND INACTIVATION.  Zengqin Deng , Grigory Maksaev, Michael Rau, Zili Xie, Hongzhen Hu, James A.J. Fitzpatrick, Peng Yuan 2025-Pos Board B295 AUTOINHIBITION OF TRPV6 CHANNEL BY INTRAMOLECULAR INTERAC- TIONS. Ruiqi Cai , Xiong Liu, Laura Hofmann, Wang Zheng, Qiaolin Hu, Veit Flockerzi, Xing-Zhen Chen 2026-Pos Board B296 HUNTING FOR THE ACTIVATING ADPR BINDING SITE OF THE NVTRPM2 CHANNEL. Balazs Toth , Iordan Iordanov, Laszlo Csanady 2027-Pos Board B297 ISOLATION OF FUNCTIONAL TEMPERATURE ACTIVATED TRANSMEM- BRANE DOMAIN OF HUMAN TRPM8. Dustin Luu , Po-Lin Chiu, Wade D. Board B298 CHARACTERIZATION OF HTRPM8 CONFORMATIONAL DYNAMIC UTILIZING SOLUTION NMR. Mubark Mebrat , Jacob K. Hilton, Danielle Morelan, Wade D. Van Horn 2029-Pos Board B299 MOLECULAR MECHANISMS UNDERLYING MENTHOL BINDING AND ACTIVATION OF TRPM8 ION CHANNEL. Lizhen Xu, Yalan Han, Xiaoying Chen, Aerziguli Aierken, Hongkun Wang, Xiancui Lu, Zhenye Zhao, Ping Liang, Wei Yang, Han Wen, Wenjun Zheng, Shilong Yang, Fan Yang 2030-Pos Board B300 MECHANISTIC AND STRUCTURAL STUDIES OF PIRT REGULATION OF TRPM8. Wade D. Van Horn , Dustin D. Luu, Minjoo Kim, Jacob K. Hilton, Camila Montano 2031-Pos Board B301 ROLE OF EPIDERMAL TRP CHANNELS IN THE DEVELOPMENT OF PRURI- TOGENIC SIGNALS. Anita Vladár , Erika Lisztes, Balázs Kelemen, Martin Hanyicska, Tamás Bíró, Balázs István Tóth 2032-Pos Board B302 PATHOPHYSIOLOGICAL CONTRIBUTION OF TRPM7 CHANNEL TO PUL- MONARY ARTERIAL HYPERTENSION. Keizo Hiraishi , Lin-Hai Kurahara, Yuanyuan Cui, Ryuji Inoue 2033-Pos Board B303 TRPM3 MEDIATES PAIN BUT NOT ITCH. Balazs Kelemen , Silvia Pinto, Erika Lisztes, Martin Hanyicska, Anita Vladár, Thomas Voets, Tamás Bíró, Balázs István Tóth 2034-Pos Board B304 THE ION CHANNEL FUNCTION OF PKD1 REVEALED BY A GAIN-OF-FUNC- TION PKD1/TRPP2 COMPLEX. Zhifei Wang, Courtney Ng, Xiong Liu, Yan Wang, R. Todd Alexander, Feng Qian, Xing-Zhen Chen, Yong Yu 2035-Pos Board B305 EFFECTS OF TRPM7 KINASE INACTIVATION IN MACROPHAGES. Jananie Rockwood, Pavani Beesetty, Masayuki Matsushita, J. Ashot Kozak 2036-Pos Board B306 ALL-OPTICAL ANALYSIS OF TRPC3/6 SIGNALLING IN MAST CELLS. Ber- nadett Bacsa, Oleksandra Tiapko , Annarita Graziani, Sanja Curcic, Klaus Board B307 ROLE OF TRPC6 ON SINGLE CELL MECHANICS IN MOUSE CARDIOMYO- CYTES. Yohei Yamaguchi , Gentaro Iribe, Keiji Naruse, Akira Takai 2038-Pos Board B308 THE ROLE OF TRPC-ORAI CHANNELS MEDIATED CALCIUM ENTRY IN HU- MAN INDUCED PLURIPOTENT STEM CELL DERIVED CARDIOMYOCYTES.  Zi Yang , Gary Aistrup Van Horn 2028-Pos Groschner 2037-Pos

2039-Pos Board B309 SPATIAL ARRANGEMENT OF TRPC1, 3 AND 6 CHANNELS IN RABBIT VENTRICULAR CARDIOMYOCYTES. Molly E. Streiff , Azmi A. Ahmad, Chris Hunter, Frank B. Sachse Ion Channel Regulatory Mechanisms II (Boards B310 - B334) 2040-Pos Board B310 DYNAMIC REGULATION OF BICARBONATE PERMEABILITY THROUGH CFTR CHANNEL BY WNK1. Yonjung Kim , Ikhyun Jun, Dong Hoon Shin, Jihoon G. Yoon, Jinsei Jung, Hyun Woo Park, Mary H. Cheng, Ivet Bahar, David C. Whitcomb, Min Goo Lee 2041-Pos Board B311 HETERODIMERIZATION OF TALK SUBUNITS. Lamyaa Khoubza , Franck Chat- elain, Sylvain Feliciangeli, Delphine Bichet, Florian Lesage 2042-Pos Board B312 THE ROLE OF HCN CHANNEL HELICES D AND E IN THE MODULATION OF CAMP AFFINITY. Alessandro Porro , Federica Gasparri, Filippo Cona, Gerhard Thiel, Federico Thei, Bina Santoro, Andrea Saponaro, Anna Moroni 2043-Pos Board B313 GATING OF BACTERIAL BETA-BARREL CHANNELS IS REGULATED BY SALT CONCENTRATION AND LIPID COMPOSITION. Deborah Aurora Perini , Anto- nio Alcaraz, Maria Queralt-Martin 2044-Pos Board B314 CYTOSKELETON DEPENDENT ACTIVATION OF TENTONIN3/TMEM150C, A NOVEL MECHANOSENSITIVE CHANNEL. Gyu-Sang Hong , Uhtaek Oh 2045-Pos Board B315 DUAL CA 2+ -DEPENDENT GATES IN HUMAN BESTROPHIN1 UNDERLIE DIS- EASE-CAUSING MECHANISMS OF GAIN-OF-FUNCTION MUTATIONS. Changyi Ji, Alec Kittredge, Austin Hopiavuori, Nancy Ward, Shoudeng Chen, Yohta Fukuda, Yu Zhang, Tingting Yang 2046-Pos Board B316 UNDERSTANDING THE PHENOMENA OF CHARGE INVERSION AND VOLTAGE GATING IN MODEL SINGLE DIGIT NANOPORES (SDNS) USING TRIVALENT IONS. Wilfred S. Russell 2047-Pos Board B317 AN EPILEPSY-ASSOCIATED LARGE CONDUCTANCE BK MUTATION MODULA- TION BY LEUCINE-RICH REPEAT-CONTAINING PROTEIN LRRC55. Jing-Jing Wang, Xiao-Mao Dong, Zhe Zhang, Qiong-Yao Tang 2048-Pos Board B318 ALLOSTERIC NETWORK ANALYSIS IN THE NMDA RECEPTOR.  Nils A. Berglund , Jose C. Flores-Canales, Birgit Schiøtt 2049-Pos Board B319 BK CHANNEL MODULATION BY THE GAMMA SUBUNIT C-TERMINAL PEP- TIDES. Guanxing Chen , Qin Li, Jiusheng Yan 2050-Pos Board B320 PI(3,4)P 2 -DEPENDENT MODULATION OF VOLTAGE DEPENDENCE IN TWO- PORE CHANNEL 3. Takushi Shimomura , Yoshihiro Kubo 2051-Pos Board B321 FUNCTIONAL AND PORE PROPERTIES OF THE LRRC8A HOMOMERIC CHANNEL ARE DISTINCT FROM THOSE OF LRRC8 CHIMERAS AND HET- EROMRES. Toshiki Yamada , Jerod S. Denton, Kevin Strange 2052-Pos Board B322 MODULATION OF A GIRK1 ACTIVE MUTANT SUBUNIT BY PROTEIN KINASE C ISOFORMS. Aishwarya Chandrashekar , Kirin Gada, Yu Xu, Takeharu Kawano, Leigh D. Plant, Diomedes E. Logothetis

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