Biophysical Society 2020 Annual Meeting

Ribosomes and Translation (Boards B218 - B231)

Chromatin and the Nucleoid II (Boards B232 - B247)

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2672-Pos Board B218 KINETIC VARIABILITY AT THE 5’ UTR OF BACTERIAL MRNA LEADS TO NAR- ROW DYNAMIC RANGE AND HIGH SENSITIVITY IN 30S RIBOSOME BIND- ING. Shiba S. Dandpat , Sujay Ray, Surajit Chatterjee, Nils G. Walter 2673-Pos Board B219 DISSECTING STRUCTURE, FUNCTION AND DYNAMICS OF MOLECULAR MACHINES BY SINGLE-MOLECULE FRET MICROSCOPY: TRANSLATION INITIATION IS REGULATED THROUGH MODULATION OF THE CONFOR- MATIONAL DYNAMICS OF THE DEAD-BOX PROTEIN EIF4A. Alexandra Z. Andreou, Ulf Harms, Linda Krause, Dagmar Klostermeier 2674-Pos Board B220 A MAXIMUM ENTROPY MODEL FOR TRNA ABUNDANCES INITIATING PROTEIN SYNTHESIS. Rebecca J. Rousseau , William Bialek 2675-Pos Board B221 MODULATION AND VISUAL DETECTION OF CROSSLINKED EF-G DURING TRANSLOCATION. Yuhong Wang , HENG YIN, Shoujun Xu 2676-Pos Board B222 KINETICS AND THERMODYNAMICS OF -1 RIBOSOMAL FRAMESHIFT- ING. Lars V. Bock , Neva Caliskan, Bee-Zen Peng, Natalia Korniy, Riccardo Belardinelli, Frank Peske, Marina V. Rodnina, Helmut Grubmueller 2677-Pos Board B223 SINGLE-MOLECULE AND ENSEMBLE ANALYSIS OF PROTEIN-MEDIATED FRAMESHIFTING. Neva Caliskan 2678-Pos Board B224 SINGLE-MOLECULE APPROACHES TO STUDY FRAMESHIFTING MECHA- NISMS AND EFFICIENCY. Lukas Pekarek , Matthias Zimmer, Anuja Kibe, Neva Caliskan 2679-Pos Board B225 ERROR-SPEED CORRELATIONS IN BIOPOLYMER SYNTHESIS. Davide Chiuchiu , Yuhai Tu, Simone Pigolotti 2680-Pos Board B226 TRNA DISSOCIATION FROM EF-TU AFTER GTP HYDROLISIS - PRIMARY STEPS AND ANTIBIOTIC INHIBITION. Malte Warias, Helmut Grubmueller , Lars V. Bock 2681-Pos Board B227 MORPHOLOGICALLY DISCRETE ER SUBDOMAINS SUPPORT THE SYN- THESIS OF DIFFERENT TYPES OF PROTEIN. Heejun Choi , Ya-Cheng Liao, Young J. Yoon, Jonathan Grimm, Luke D. Lavis, Robert H. Singer, Jennifer Lippincott-Schwartz 2682-Pos Board B228 COMPUTATIONAL DESIGN AND INTERPRETATION OF SINGLE-RNA TRANS- LATION EXPERIMENTS. Luis U. Aguilera , Kenneth Lyon, William Raymond, Tatsuya Morisaki, Timothy J. Stasevich, Brian Munsky 2683-Pos Board B229 USING SIMULATIONS TO IDENTIFY PRECISE SINGLE-MOLECULE PROBES FOR RIBOSOME DYNAMICS. Asem H. Hassan , Paul C. Whitford 2684-Pos Board B230 OPTIMIZING RECOMBINANT PROTEIN EXPRESSION WITH SYNONYMOUS CODONS. Daniel Wong, Kam-Ho Wong, Gregory Boël, John F. Hunt, Daniel P. Aalberts 2685-Pos Board B231 EXPANDING MASS SPECTROMETRY TOOLBOX FOR RNA MODIFICATION PROFILING. Anna Popova , Luigi D’Ascenzo, James R. Williamson

2686-Pos Board B232 INFLUENCE OF MICROPILLAR INDUCED DEFORMATION ON CHROMATIN ARCHITECTURE IN REGULATING STEM CELL DIFFERENTIATION.  Vasundhara Agrawal , Xinlong Wang, Guillermo Ameer, Vadim Backman 2687-Pos Board B233 CHROMATIN FOLDING COORDINATE AND LANDSCAPE UNRAVELED BY DEEP LEARNING ANALYSIS OF SINGLE-CELL IMAGING DATA. Wenjun Xie , Yifeng Qi, Bin Zhang 2688-Pos Board B234 MESOSCALE PHASE SEPARATION OF CHROMATIN IN THE NUCLE- US. Gaurav Bajpai, Daria A. Pavlov, Dana Lorber, Talila Volk, Samuel Safran 2689-Pos Board B235 INFERRING RADIAL ORGANIZATION OF CHROMOSOMAL TERRITORIES FROM HI-C DATA. Priyojit Das , Jacob T. Sanders, Tongye Shen, Rachel P. McCord 2690-Pos Board B236 LANDSCAPE OF MULTIVALENT CHROMATIN INTERACTIONS IN TRAN- SCRIPTIONALLY ACTIVE LOCI. Alan Perez-Rathke, Qiu Sun, Boshen Wang, Valentina Boeva, Zhifeng Shao, Jie Liang 2691-Pos Board B237 CREATING AN INTEGRATED LANDSCAPE OF HUMAN IPSC NUCLEAR STATES. Christopher L. Frick , Susanne M. Rafelski 2692-Pos Board B238 DISORDERED CHROMATIN PACKING REGULATES ENSEMBLE GENE EX- PRESSION AND PHENOTYPIC PLASTICITY. Ranya Virk , Wenli Wu, Luay M. Almassalha, Greta M. Bauer, Yue Li, David VanDerway, Jane Frederick, Di Zhang, Adam Eshein, Igal Szleifer, Vadim Backman 2693-Pos Board B239 IMPROVING CHEMOTHERAPY TREATMENT EFFICACY WITH CHROMA- TIN PROTECTION THERAPIES.  Jane Frederick , Greta Wodarcyk, Luay M. Almassalha, Wenli Wu, David VanDerway, Ranya Virk, Vadim Backman 2694-Pos Board B240 BRIDGING CHROMATIN NANOIMAGING AND MOLECULAR MODELING: CHROMATIN PACKING AS A REGULATOR OF TRANSCRIPTIONAL HETERO- GENEITY IN CARCINOGENESIS. Vadim Backman 2695-Pos Board B241 EXPERIMENTALLY-DRIVEN MODELS OF BACTERIAL CHROMOSOMES.  Michael Feig 2696-Pos Board B242 Travel Awardee POLYMER MODELING OF WHOLE-NUCLEUS DIPLOID GENOME ORGANI- ZATION. Yifeng Qi , Bin Zhang 2697-Pos Board B243 MODELING HIGH-ORDER CHROMATIN STRUCTURE IN SINGLE CELLS.  Kai Huang , Vadim Backman, Igal Szleifer 2698-Pos Board B244 LARGE-SCALE HETEROPOLYMER MODEL OF CHROMATIN DYNAMICS AND MECHANICS. Anne Shim , Kai Huang, Vadim Backman, Igal Szleifer 2699-Pos Board B245 THE EFFECT OF NUCLEAR ENVELOPE ON CHROMATIN ARCHITECTURE IN DROSOPHILA MELANOGASTER : MODELING OF THREE-DIMENSIONAL INTERPHASE CHROMOSOME ORGANIZATION.  Igor S. Tolokh , Nicholas A. Kinney, Igor V. Sharakhov, Alexey V. Onufriev

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