Biophysical Society 2020 Annual Meeting

2700-Pos Board B246 PREDICTING THE ORGANIZATION OF MITOTIC CHROMOSOMES US- ING THE GENERALIZED ROUSE MODEL. Atreya Dey , Guang Shi, Dave Thirumalai 2701-Pos Board B247 PREDICTING STRUCTURAL ENTROPY OF TOPOLOGICALLY ASSOCIATING DOMAINS (TADS) OF CHROMATIN FROM EPIGENETIC INFORMATION.  Lin Du , Boshen Wang, Alan Perez-Rathke, Jie Liang

2714-Pos Board B260 SYNAPTOTAGMIN-1/CA 2+ OVERCOMES INEFFICIENCY OF SNARE COMPLEX IN DILATING THE FUSION PORE. Ryan Khounlo 2715-Pos Board B261 CHOLESTEROL ALTERS PHYSICAL PROPERTIES OF THE TARGET MEM- BRANE TO FACILITATE INFLUENZA MEMBRANE FUSION AT THE SINGLE- PARTICLE LEVEL. Katherine N. Liu , Steven G. Boxer Protein-Lipid Interactions: Channels (Boards B262 - B272) 2716-Pos Board B262 Travel Awardee PHOSPHATE POSITION ON PHOSPHOINOSITIDES IS KEY IN MEDIATING TMEM16A CURRENTS IN XENOPUS LAEVIS OOCYTES. Maiwase Tembo , Anne E. Carlson 2717-Pos Board B263 NICOTINIC ACETYLCHOLINE RECEPTORS LIPID PREFERENCES WITHIN COMPLEX QUASI-NATIVE MEMBRANES. LiamM. Sharp , Kristen N. Woods, Grace H. Brannigan 2718-Pos Board B264 INVESTIGATING PROTEIN-LIPID INTERACTIONS OF MTHK AND NATIVE BACTERIAL MEMBRANE LIPIDS. Daniel Quetschlich , Mark T. Agasid, Ra- chel A. Davis, Zara A. Sands, Idlir Liko, Mark S. Sansom, Phillip J. Stansfeld, Carol V. Robinson 2719-Pos Board B265 LIPID-DEPENDENT MODULATION OF CARDIAC ION CHANNEL ACTIVITY AS AN ANTI-ARRHYTHMIC THERAPY IN LONG-QT SYNDROME. Haydee Mesa Galloso , Mario E. Valdes-Tresanco, Nandhitha Subramanian, Valentina Corradi, Williams E. Miranda, Meruyert Kudaibergenova, Sara I. Liin, Peter H. Larsson, Sergei Y. Noskov, Peter D. Tieleman 2720-Pos Board B266 RUGGEDIZED CHIP-BASED LIPID BILAYER ARRAYS WITH PERMEABLE MULTI-MAC SUPPORT. Daniel L. Burden , Amanda J. Smith, Theo Larsen, Lisa M. Burden 2721-Pos Board B267 ELASTIC MEMBRANE DEFORMATIONS DETERMINE INTERACTION OF GRAMICIDIN A DIMERS, MONOMERS, AND PAIRS THEREBY MODULATING THE LIFETIME OF THE CONDUCTING STATE. Oleg V. Kondrashov, Timur R. Galimzyanov, Tatyana I. Rokitskaya, Elena A. Kotova, Yuri N. Antonenko, Sergey A. Akimov 2722-Pos Board B268 MOLECULAR PROCESS OF GRAMICIDIN A DIMERIZATION DETERMINED WITH MILLISECONDS ATOMISTIC SIMULATIONS AND MACHINE LEARN- ING. Delin Sun 2723-Pos Board B269 A NETWORK OF PIP 2 BINDING SITES REGULATE GATING OF THE CALCIUM- ACTIVATED CHLORIDE CHANNEL TMEM16A. Tao Jiang , Kuai Yu, Yuanyuan Cui, H. Criss Hartzell, Emad Tajkhorshid 2724-Pos Board B270 MOLECULAR SIMULATIONS OF KIR-CHOLESTEROL INTERACTIONS UNCOV- ER CHOLESTEROL-MEDIATED DE-COUPLING OF FUNCTIONAL DOMAINS IMPORTANT FOR GATING. Nicolas Barbera , Belinda S. Akpa, Irena Levitan 2725-Pos Board B271 MOLECULAR MECHANISMS OF HUMAN ERG1 CHANNEL BLOCKADE BY CERAMIDES. Williams E. Miranda , Jiqing Guo, Valentina Corradi, Haydee Mesa Galloso, Peter D. Tieleman, Henry J. Duff, Sergei Y. Noskov

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Membrane Fusion and Non-Bilayer Structures (Boards B248 - B261)

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2702-Pos Board B248 COMPLEXIN 1 AND SYNAPTOTAGMIN 1 COMPETE FOR MEMBRANE BINDING IN A PIP2 DEPENDENT MANNER. Qian Liang , Volker Kiessling, Binyong Liang, Lukas K. Tamm, David S. Cafiso 2703-Pos Board B249 A MODEL FOR MYOMERGER FUNCTION IN MYOBLAST FUSION. Gonen Golani , Evgenia Leikina, Douglas P. Millay, Leonid V. Chernomordik, Michael M. Kozlov 2704-Pos Board B250 CALCIUM IONS ENHANCE ENTRY OF EBOLA VIRUS BY DIRECTLY TARGET- ING THE FUSION PEPTIDE. Liqi Lai , Lakshmi Nathan, Jean K. Miller, Jack H. Freed, Gary R. Whittaker, Susan Daniel 2705-Pos Board B251 DIFFERENTIATING ANTIBODY NEUTRALISATION MECHANISMS USING A SINGLE VIRUS-ASSAY. Anjali Sengar , Rebecca R. Pompano, Peter Kasson 2706-Pos Board B252 STRUCTURAL DETERMINANTS OF LIPID MEMBRANE THICKENING AT CLOSE DISTANCES. Leonard P. Heinz , Agata Witkowska, Helmut Grubm- ueller, Reinhard Jahn 2707-Pos Board B253 INVERTED CUBIC (Q II ) PHASE STABILIZING EFFECTS OF MEMBRANE AC- TIVE PEPTIDES AS AN INDEX OF ANTIMICROBIAL PEPTIDE (AMP) AND FUSION PEPTIDE ACTIVITY. David P. Siegel 2708-Pos Board B254 RESOLVING KINETIC INTERMEDIATES DURING THE REGULATED ASSEM- BLY AND DISASSEMBLY OF FUSION PORES. Huan Bao 2709-Pos Board B255 DECONVOLUTION OF INFLUENZA A VIRAL BINDING AND FUSION WITH A CHEMICALLY-DEFINED GLYCOCALYX. Elizabeth R. Webster , Corleone S. Delaveris, Carolyn R. Bertozzi, Steven G. Boxer 2710-Pos Board B256 IMPACTS OF BIOCHEMICAL COMPLEXITY ON CLIMATE-RELEVANT PROP- ERTIES OF MODEL MARINE AEROSOLS. Abigail C. Dommer , Rommie E. Amaro 2711-Pos Board B257 KINETIC AND CELLULAR AUTOMATON MODELS OF WEST NILE VIRUS HEMIFUSION. Abraham Park , Robert J. Rawle 2712-Pos Board B258 SINGLE VIRUS INVESTIGATION OF SENDAI VIRUS BINDING AND FUSION TO SUPPORTED LIPID BILAYERS. Amy Lam , Nandini Seetharaman, Robert J. Rawle 2713-Pos Board B259 TWO FORMS OF OPA1 COOPERATE TO COMPLETE MITOCHONDRIA INNER MEMBRANE FUSION. Yifan Ge , Sivakumar Boopathy, Xiaojun Shi, Julie L. McDonald, AdamW. Smith, Luke Chao

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