Biophysical Society 2020 Annual Meeting

Lili Zhang , McMaster University, Canada 246-Pos, B77

Elizabeth Erler , Swarthmore College 1023-Pos, B91

USING FLUORESCENCE CORRELATION SPECTROSCOPY TO ACCURATELY MEASURE PROTEIN CONCENTRATION GRADIENTS IN THE PRESENCE OF NOISE AND PHOTOBLEACHING Monday, February 17 Jorge Alegre-Cebollada , CNIC, Spain 795-Plat INDEPENDENT TUNING OF VISCOUS AND ELASTIC PROPERTIES OF PROTEIN BIOMATERIALS Eduardo U. Anaya , University of New Mexico 1200-Pos, B268 INNATE ANTIFUNGAL IMMUNE RECEPTOR, DECTIN-1, UNDERGOES LIGAND-INDUCED OLIGOMERIZATION WITH HIGHLY STRUCTURED β-GLUCANS AND AT FUNGAL CELL CONTACT SITES Baris O. Aydintug , University of Colorado Denver 1467-Pos, B535 PROTON TRANSPORT THROUGH E. COLI CLC CHLORIDE/PROTON ANTIPORTER IN THE PRESENCE OF BOUND FLUORIDE Yousef Bagheri , University of Massachusetts Amherst 1147-Pos, B215 QUANTITATIVE ASSESSMENT OF THE DYNAMIC MODIFICATION OF LIPID-DNA PROBES ON LIVE CELL MEMBRANES Matthieu P. Benoit , Albert Einstein College 856-Plat CHEMO-MECHANICAL CYCLE DIVERSITY IN THE KINESIN SUPERFAMILY REVEALED BY CRYO-EM Abrar A. Bhat , National Centre for Biological Sciences, India 801-Plat DIFFERENTIAL ACTIN BINDING AFFINITY LEADS TO PROTEIN SORTING IN A RECONSTITUTED ACTIVE COMPOSITE LAYER Madolyn Britt , University of Maryland, College Park 65-Plat, B305 MSCS IS A CRITICAL COMPONENT FOR OSMOTIC SURVIVAL OF VIBRIO CHOLERAE Joshua Brockman , Emory University 1390-Pos, B458 SUPER-RESOLVED MEASUREMENT OF PICONEWTON RECEPTOR FORCES VIA TENSION-PAINT Yunfeng Chen , The Scripps Research Institute 786-Plat DISTINCTIVE MECHANO-SENSITIVITY OF FOCAL ADHESION INTEGRINS

PROBING THE M1-M2 INTERACTION IN INFLUENZA A VIRUS USING SITE-DIRECTED SPIN LABELING EPR IN LIPID BILAYER NANODISCS Joy Franco , Stanford University 1409-Pos, B477 AN IN VITRO SYSTEM FOR STUDYING NEMATODE MECHANOSENSORY NEURONS Sarah Innes-Gold , University of California, Santa Barbara 976-Pos, B44 SINGLE-MOLECULE MECHANICAL MEASUREMENTS OF THE HYALURONAN-AGGRECAN BOTTLEBRUSH Meghna Gupta , University of California, San Francisco 1026-Pos, B94 STRUCTURAL ANALYSIS OF A PHOSPHATE ‘TRANSCEPTOR’ Shanna Hamilton , Ohio State University Medical Center 1257-Pos, B325 HYPERACTIVITY OF RYR2 IN CARDIAC DISEASE IS EXACERBATED BY CALCIUM LEAK-INDUCED MITOCHONDRIAL ROS Per Niklas Hedde , University of California, Irvine 1211-Pos, B279 PAIR CORRELATION ANALYSIS REVEALS BARRIERS TO NATURAL KILLER CELL RECEPTOR MOTION AT THE SYNAPSE Maxx Holmes , University of Leeds, United Kingdom 838-Plat SUB-CELLULAR HETEROGENEITY IN SERCA DETERMINES SPATIAL MEMBRANE POTENTIAL IS VITAL FOR RAPID PERMEABILIZATION OF PLASMA MEMBRANES AND LIPID BILAYERS BY THE ANTIMICROBIAL PEPTIDE LACTOFERRICIN B Brett A. Israels , University of Oregon 915-Plat SUB-MICROSECOND SINGLE-MOLECULE FRET STUDIES OF SINGLE- STRANDED DNA CONFORMATION FLUCTUATIONS MEDIATED BY SINGLE-STRANDED DNA BINDING PROTEINS Joseph Mathew Kalappurakkal , National Centre for Biological Sciences, India 924-Plat PLASMA MEMBRANE NANODOMAINS AS AN INTEGRATOR OF SUBSTRATE ENCODED MECHANO-CHEMICAL SIGNALS James Keener , University of Arizona 1181-Pos, B249 MEASURING MEMBRANE PROTEIN-LIPID INTERACTIONS IN NANODISCS WITH NATIVE MASS SPECTROMETRY Newsha Koushki , McGill University, Canada 1243-Pos, B311 YAP ACTIVITY DIRECTLY SCALES WITH NUCLEAR DEFORMATION AND LAMIN A DISTRIBUTION CALCIUM DYNAMICS IN CARDIOMYOCYTES Farzana Hossain , Shizuoka University, Japan 1167-Pos, B235

α5β1 AND αVβ3 IN CONFORMATIONAL CHANGES Sara J. Codding , University of Maryland, Baltimore 1291-Pos, B359

MEASURING INTRINSIC LIGAND DYNAMICS OF HERG POTASSIUM CHANNELS USING THE UNNATURAL AMINO ACID L-ANAP AND TM-FRET Kirsten Cottrill , Emory University 1174-Pos, B242 DETERMINING THE LIPID ENVIRONMENT AND INTERACTIONS OF CFTR

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