Biophysical Society 2020 Annual Meeting

Savannah J. West , University of Texas Health Graduate School of Biomedical Sciences 1984-Pos, B254 REGULATION OF ORAI1/STIM1 FUNCTION BY S-ACYLATION Wednesday, February 19 Yuriana Aguilar-Sanchez , Rush University Medical Center 2774-Pos, B320 LUMINAL CALCIUM CONTROL OF TYPE-1 INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR Cody P. Aplin , University of Minnesota Duluth 2485-Pos, B31 INVESTIGATING NOVEL HETERO-FRET BIOSENSORS FOR ENVIRONMENTAL IONIC STRENGTH USING EXPERIMENTAL AND THEORETICAL APPROACHES Olivia Byun , McMaster University, Canada 2557-Pos, B103 MECHANISM OF ALLOSTERIC INHIBITION OF PLASMODIUM FALCIPARUM CGMP-DEPENDENT PROTEIN KINASE Po-Chia Chen , EMBL Heidelberg, Germany 2547-Pos, B93 AB-INITIO PREDICTION OF NMR SPIN-RELAXATION PARAMETERS FROM MD SIMULATIONS Zhijie Chen , University of California, Berkeley 2655-Pos, B201 SINGLE-MOLECULE NAVIGATION OF THE NUCLEOSOMAL TRANSCRIPTION LANDSCAPE Yuan-I Chen , University of Texas at Austin 3012-Pos, B558 COMPARISON OF IN-VITRO AND IN-VIVO DNA HYBRIDIZATION KINETICS USING 3D SINGLE-MOLECULE TRACKING METHOD Sami Chu , University of Minnesota 2909-Pos, B455 OBSERVING THE MYOSIN SUPER-RELAXED STATE (SRX) IN CARDIAC THICK FILAMENTS Han Chow Chua , University of Copenhagen, Denmark 2443-Plat THE SODIUM LEAK CHANNEL COMPLEX IS MODULATED BY VOLTAGE AND EXTRACELLULAR CALCIUM Peter J. Chung , University of Chicago 2641-Pos, B187 ALPHA-SYNUCLEIN DETECTS AND PREFERENTIALLY BINDS TO OSMOTICALLY TENSE SYNAPTIC VESICLE-LIKE MEMBRANES Claudia Crocini , University of Colorado Boulder 2797-Pos, B343 POST-PRANDIAL INOTROPIC RESPONSE IN PYTHON CARDIOMYOCYTES IS SUPPORTED BY DISTINCT METABOLIC ADAPTATION Tapojyoti Das , Weill Cornell Medicine 2646-Pos, B192 THE STRUCTURAL BASIS OF OPPOSING FUNCTIONS OF ALPHA- SYNUCLEIN IN VESICLE EXOCYTOSIS

Brendan R. Deal , Emory University 3045-Pos, B591 FINE-TUNING SPHERICAL NUCLEIC ACID BINDING THROUGH HETEROMULTIVALENCY AND SPATIAL PATTERNING Karissa Dieseldorff Jones , Florida State University 2904-Pos, B450 SEX DIFFERENCES IN REGULATING THE CARDIAC TRANSCRIPTOME WITHIN A MURINE MODEL FOR HYPERTROPHIC CARDIOMYOPATHY Eric Figueroa , Vanderbilt University 2873-Pos, B419 CYSLT1 RECEPTOR ANTAGONISTS PRANLUKAST AND ZAFIRLUKAST INHIBIT LRRC8-MEDIATED VOLUME REGULATED ANION CHANNELS INDEPENDENTLY OF THE RECEPTOR Ewan D. Fowler , University of Bristol, United Kingdom 2784-Pos, B330 LATE CA 2+ SPARK ARRHYTHMOGENESIS IN FAILING CARDIAC MYOCYTES Gabriel Jose Fuente Gomez , University of Tennessee 2602-Pos, B148 LIGAND BINDING STUDIES OF A TRIMETHOPRIM-RESISTANT DIHYDROFOLATE REDUCTASE BY FLUORINE NMR Karola Gerecht , King’s College London, United Kingdom 2379-Plat, P53 DEAMIDATION AS A MOLECULAR TIMER FOR CELL DEATH Bassam G. Haddad , Portland State University 2435-Plat, VISUALIZATION OF PROTEIN-LIPID INTERACTIONS IN CONNEXIN-46/50 INTERCELLULAR CHANNELS BY CRYO-EM AND MD-SIMULATION Joshua A. Johnson , Ohio State University 3047-Pos, B593 RECIPROCAL CONTROL OF HIERARCHICAL DNA ORIGAMI- NANOPARTICLE ASSEMBLIES Taylor Jones , Stanford University 2981-Pos, B527 LIGHT-INDUCIBLE GENERATION OF MEMBRANE CURVATURE IN LIVE CELLS WITH ENGINEERED BAR DOMAIN PROTEINS Taryn M. Kay , University of Minnesota Duluth 3008-Pos, B554 SINGLE-MOLECULE STUDIES OF HETERO-FRET BIOSENSORS TO ENVIRONMENTAL IONIC STRENGTH USING DIFFERENT MODALITIES OF FLUORESCENCE CORRELATION SPECTROSCOPY Shamir A. Khan , Wichita State University 2502-Pos, B48 IMPROVING PERSONALIZED MEDICINE THROUGH SYSTEMATIC PROTEIN ENGINEERING OF LDH Alena Khmelinskaia , University of Washington 2531-Pos, B77 BREAKING THE SYMMETRY OF PROTEIN ASSEMBLIES: STRUCTURAL FLEXIBILITY AS A DE NOVO DESIGN PRINCIPLE

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