Biophysical Society 2020 Annual Meeting

139-Plat 4:15 pm VISUALIZING ENDOGENOUS RNA POLYMERASE II PHOSPHORYLATION DY- NAMICS AT A SINGLE GENE.  Linda S. Forero Quintero , William Raymond, Tetsuya Handa, Matthew Saxton, Tatsuya Morisaki, Edouard Bertrand, Hiroshi Kimura, Brian Munsky, Timothy J. Stasevich 140-Plat 4:30 pm SINGLE-MOLECULE ANALYSIS REVEALS THE MECHANISM FOR DNA OPEN- ING IN TRANSCRIPTION INITIATION.  Abhishek Mazumder, Richard H. Ebright, Achillefs N. Kapanidis 141-Plat 4:45 pm TRACKING SINGLE RNAP ENZYME STEPS AND STATE TRANSITIONS DUR- ING ELONGATION AND PAUSING WITH NANOPORE TWEEZERS.  Ian C. Nova , Abhishek Mazumder, Jonathan M. Craig, Andrew H. Laszlo, Matthew T. Noakes, Henry D. Brinkerhoff, Shuya Yang, Jonathan W. Mount, Jesse Huang, Richard H. Ebright, Jens H. Gundlach 142-Plat 5:00 pm Travel Awardee VISUALIZING DYNAMIC TETHERING OF ARGONAUTE TO SINGLE MRNA IN LIVE HUMAN CELLS REVEALS THE MECHANISM OF MIRNA-MEDIATED TRANSLATIONAL SILENCING.  Charlotte A. Cialek , Taiowa A. Montgomery, Timothy J. Stasevich 143-Plat 5:15 pm STUDYING THE DYNAMICS OF PARTIALLY FOLDED NASCENT PEPTIDES ON THE RIBOSOME USING PET-FCS APPROACH. Manisankar Maiti , Marija Liutkute, Ekaterina Samatova, Joerg Enderlein, Marina V. Rodnina 144-Plat 5:30 pm DAMAGE SEARCH MECHANISM OF HUMAN NER PROTEIN XPC-RAD23B AT THE SINGLE-MOLECULE LEVEL.  Na Young Cheon , Ja Yil Lee 145-Plat 5:45 pm DNA BRIDGING BY THE HOMOLOGOUS RECOMBINATION COMPONENT CTIP INVESTIGATED ON THE SINGLE DNA MOLECULE LEVEL.  Robin Öz, Sean Michael Howard, Hanna Törnkvist, Sriram KK, Petr Cejka, Fredrik Westerlund Platform Microtubules, Actin, Dynamics, and Associated Proteins 4:00 pm - 6:00 pm, Room 25ABC Co-Chairs Richard McKenney, University of California, Davis Kristen Skruber, University of Florida 146-Plat 4:00 pm MOLECULAR MECHANISM FOR DIFFERENTIAL FORCE-REGULATED ACTIN BINDING BY VINCULIN AND ALPHA-CATENIN.  Lin Mei , Santiago Espinosa de los Reyes, Matthew J. Reynolds, Shixin Liu, Gregory M. Alushin 147-Plat 4:15 pm MICROTUBULES GATE TAU CONDENSATION TO SPATIALLY REGULATE MICROTUBULE FUNCTIONS.  Ruensern Tan, Aileen Lam, Tracy Tan, Jisoo Han, Dan W. Nowakowski, Sergi Simo, Michael Vershinin, Kassandra M. Ori-McKenney, Richard J. McKenney 148-Plat 4:30 pm THE C-TERMINAL DOMAIN OF TALIN FORMS A FORCE-RESPONSIVE, DI- RECTIONAL CATCH BOND TO F-ACTIN.  Leanna M. Owen , Nicolas A. Bax, William I. Weis, Alexander R. Dunn 149-Plat 4:45 pm Travel Awardee THE INNER JUNCTION COMPLEX OF THE CILIA IS AN INTERACTION HUB THAT INVOLVES TUBULIN POST-TRANSLATIONAL MODIFICATIONS.  Ahmad Khalifa , Muneyoshi Ichikawa, Daniel Dai, Corbin Black, Katya Peri, Thomas McAlear, Shintaroh Kubo, Simon Veyron, Shun Kai Yang, Kaustuv Basu, Javier Vargas, Jean-Francois Trempe, Susanne Bechstedt, Khanh Huy Bui

150-Plat 5:00 pm PROFILIN-1 CONTROLS ACTIN NETWORK ORGANIZATION AND HOMEO- STASIS THROUGH COORDINATION WITH OTHER ASSEMBLY FACTORS.  Kristen Skruber , Peyton Warp, Jessica Henty-Ridilla, Eric Vitriol 151-Plat 5:15 pm COLLECTIVE MECHANOCHEMICAL EFFECTS IN MICROTUBULE DYNAMICS: THEORY AND SIMULATIONS.  Kristian Blom , Maxim Igaev, Aljaz Godec, Helmut Grubmueller 152-Plat 5:30 pm PATHWAYS FOR ACTIN POLYMERIZATION MEDIATED BY FORMINS.  Naomi Courtemanche 153-Plat 5:45 pm MICROTUBULE TREADMILLING RECONSTITUTED WITH A MINIMAL-COM- PONENT IN VITRO SYSTEM.  Goker Arpag, Elizabeth Lawrence, Marija Zanic Platform Optical and Force Microscopy 4:00 pm - 6:00 pm, Room 30ABC Co-Chairs Alvaro Alonso-Caballero, Columbia University Megan Kern, University of North Carolina Chapel Hill 154-Plat 4:00 pm ANISOTROPY RESOLVED MULTIDIMENSIONAL EMISSION SPECTROSCOPY (ARMES) AND CHEMOMETRIC MODELLING TO STUDY FÖRSTER RESO- NANCE ENERGY TRANSFER (FRET) PROCESSES.  Fiona Gordon 155-Plat 4:15 pm RAMAN SPECTROSCOPY AND ARTIFICIAL INTELLIGENCE TO PREDICT THE BAYESIAN PROBABILITY OF BREAST CANCER.  Ragini Kothari , Veronica Jones, Dominique Mena, Viviana Bermudez, Youkang Shon, Jennifer Smith, Daniel Schmolze, Philip Cha, Yuman Fong, Michael Storrie-Lom- bardi 156-Plat 4:30 pm NONSPECIFIC PROBE BINDING AND AUTOMATIC GATING IN FLOW CYTOMETRY AND FLUORESCENCE ACTIVATED CELL SORTING (FACS).  Bhaven A. Mistry , Tom Chou 157-Plat 4:45 pm GOLD NANOISLAND SUBSTRATES AS UNIFORM SERS SUBSTRATES FOR SENSITIVE DETECTION OF BONE MARROW-DERIVED MESENCHYMAL STROMAL CELLS FINGERPRINTS.  Adrianna Milewska , Vesna Zivanovic, Virginia Merk, Ólafur E. Sigurjónsson, Janina S. Kneipp, Kristjan Leosson 158-Plat 5:00 pm A THERMODYNAMIC FRAMEWORK FOR DYNAMIC FORCE SPECTROS- COPY.  Alan Y. Liu , Todd A. Sulchek 159-Plat 5:15 pm COMBINED AFM AND VERTICAL LIGHT SHEET MICROSCOPY TO CORRE- LATE ACTIN ACCUMULATION TO ENGULFMENT FORCES DURING PHAGO- CYTOSIS. Megan E. Kern , Evan F. Nelsen, Chad M. Hobson, Joe Hsiao, E. Timothy E. O’Brien, Michael R. Falvo, Richard Superfine 160-Plat 5:30 pm BIOMOLECULAR DATA ASSIMILATION TO INTEGRATE HIGH-SPEED ATOM- IC FORCE MICROSCOPY MEASUREMENT AND MOLECULAR SIMULATION.  Sotaro Fuchigami , Toru Niina, Shoji Takada 161-Plat 5:45 pm HIGH FORCE MAGNETIC TWEEZERS REVEAL THAT BACTERIAL ADHESION PILI ACT AS MEGADALTON-SCALE SCHOCK ABSORBERS.  Alvaro Alonso- Caballero , Rafael Tapia-Rojo, Carmen L. Badilla, Julio M. Fernandez

S U N D A Y

24