Biophysical Society 2020 Annual Meeting

Monday, February 17

Platform Membrane Receptors and Signal Transduction 8:15 am - 10:15 am, Ballroom 20BC Co-Chairs Deborah Leckband, University of Illinois at Urbana-Champaign Carl-Mikael Suomivuori, Stanford University 782-plat 8:15 am RATIONALIZING THE TRANSPORT OF TROJAN HORSE COMPOUNDS FOR CROSSING THE OUTER MEMBRANE OF GRAM- BACTERIA.  Stefan Milen- kovic, Igor V. Bodrenko, Mariano Andrea Scorciapino, Matteo Ceccarelli 783-plat 8:30 am ATOMISTIC MODELING OF NEURO-CARDIOVASCULAR COUPLING MODULATION.  Kevin R. DeMarco, John R.D. Dawson, Slava Bekker, Vladimir Yarov-Yarovoy, Colleen E. Clancy, Igor Vorobyov 784-plat 8:45 am LARGE CONDUCTANCE CA 2+ -ACTIVATED K + CHANNELS REGULATE LPS- INDUCED CYTOKINE SECRETION FROM ALVEOLAR EPITHELIAL AND ENDOTHELIAL CELLS.  Tatiana Zyrianova , Benjamin Lopez, Andy Liao, Charles Gu, Leanne Wong, Michela Ottolia, Riccardo Olcese, Andreas Schwingshackl 785-plat 9:00 am AFFINITY AND STOICHIOMETRY OF E-CADHERIN/EGFR COMPLEXES- RELEVANCE TO PROLIFERATION AND FORCE TRANSDUCTION.  Deborah E. Leckband , Taylor P. Light, Vinh H. Vu, Brendan G. Sullivan, Kalina 9:15 am Travel Awardee DISTINCTIVE MECHANO-SENSITIVITY OF FOCAL ADHESION INTEGRINS Α5Β1 AND ΑVΒ3 IN CONFORMATIONAL CHANGES.  Yunfeng Chen , Fang Kong, Zhenhai Li, Lining Ju, Steve Park, Andres J. Garcia, Paul Mould, Martin J. Humphries, Cheng Zhu 787-plat 9:30 am Travel Awardee MOLECULAR MECHANISM OF BIASED SIGNALING IN A PROTOTYPICAL G-PROTEIN-COUPLED RECEPTOR.  Carl-Mikael Suomivuori , Naomi R. Latorraca, Laura M. Wingler, Stephan Eismann, Matthew C. King, Alissa L.W. Kleinhenz, Meredith A. Skiba, Dean P. Staus, Andrew C. Kruse, Robert J. Lefkowitz, Ron O. Dror 788-plat 9:45 am CHARACTERIZATION OF A 2A R AND G PROTEIN COUPLING BY SURFACE PLASMON RESONANCE.  Kirsten S. Koretz , Claire McGraw, Anne S. 10:00 am INVESTIGATING THE HOMOTYPIC AND HETEROTYPIC INTERACTIONS OF ERBB RECEPTOR TYROSINE KINASES.  Soyeon Kim , AdamW. Smith Platform Bioengineering, Biosurfaces, and Biomaterials 8:15 am - 10:15 am, Room 23ABC Co-Chairs Henry Brinkerhoff, Delft University of Technology, The Netherlands Elizabeth Yates, United States Naval Academy 790-plat 8:15 am SUPRACELLULAR ACTIN CABLES AND ACTOMYOSIN-BASED CONTRAC- TION IN CARDIAC MORPHOGENESIS.  Christopher McFaul , Negar Balaghi, Christopher M. Yip, Rodrigo Fernandez-Gonzalez Hristova 786-plat Robinson 789-plat

M O N D A Y

Graduate Student Breakfast 7:30 am - 8:30 am, Room 28CDE Support contributed by the Burroughs Wellcome Fund.

This breakfast presents an opportunity for graduate student Annual Meeting attendees to meet and discuss the issues they face in their cur- rent career stage. Limited to the first 100 attendees. Speaker Martin Guthold, Wake Forest University Jeanne Small, NSF Registration/Exhibitor Registration 7:30 am - 5:00 pm, Lobby G Poster Viewing 8:00 am - 10:00 pm, Exhibit Hall Symposium Molecular Motors 8:15 am - 10:15 am, Ballroom 20A Chair Bik-Kwoon Tye, Hong Kong University of Science and Technology 776-symp 8:15 am RAD52 DNA REPAIR PROTEIN IS A GATEKEEPER THAT PROTECTS DNA REPLICATION FORKS FROM REGRESSION BY FORK REVERSAL MOTORS.  Masayoshi Honda, Emeleeta A. Paintsil, Maria Spies No Abstract 8:45 am RNA HELICASES AND SWITCHES: MOLECULAR MOTORS IN RNA BIOL- OGY.  Anna Marie Pyle 777-symp 9:15 am PROCESSIVE CHITINASE, A BURNT-BRIDGE BROWNIAN MOTOR HYDRO- LYZING CRYSTALLINE POLYSACCHARIDE.  Ryota Iino 778-symp 9:45 am EVOLUTION OF THE EUKARYOTIC ORIGIN RECOGNITION COMPLEX.  Bik-Kwoon Tye , Shuk Kwan C. Lee, Wai Hei H. Lam, Yuanliang Zhai Symposium Chair Jeanne Hardy, University of Massachusetts Amherst 779-symp 8:15 am IDENTIFYING AND EXPLOITING CRYPTIC POCKETS.  Greg R. Bowman 780-symp 8:45 am BITOPIC AND PERIPHERAL MEMBRANE PROTEINS AS DRUG TARGETS: BROADER BIOPHYSICAL INSIGHT FROM BIOMEMBRANE SIMULATIONS THAT TRANSCENDS THE “LOCK AND KEY” PARADIGM.  Alex Bunker No Abstract 9:15 am THE CHOREOGRAPHY OF A PROTEIN’S DANCE AT THE HEART OF DRUG DESIGN.  Dorothee Kern 781-symp 9:45 am TARGETING RARE CONFORMATIONAL STATES TO ACHIEVE SELECTIVE CASPASE PROTEASE INHIBITION.  Jeanne Hardy Pharmaceutical Biophysics 8:15 am - 10:15 am, Ballroom 20D

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