Biophysical Society 59th Annual Meeting Program Guide

2560-P lat 2:15 pm TRANSCRIPTION KINETICS HETEROGENEITY OF HIGHLY MOBILE IDENTICAL GENES REVEALED BY SIMULTANEOUS MEASUREMENT AT THE SINGLE CELL LEVEL. Enrico Gratton , Paolo Annibale 2561-P lat 2:30 pm DYNAMICS OF GREB INTERACTIONS WITH RNA POLYMERASE: HOW A REGULATORY PROTEIN MAY PATROL THE GENOME FOR TRANSCRIPTION COMPLEXES TO RESCUE. Larry E. Tetone , Larry J. Friedman, Melisa L. Osborne, Harini Ravi, Scotty Kyzer, Rachel A. Mooney, Robert Landick, Jeff Gelles 2562-P lat 2:45 pm A SINGLE MOLECULE PERSPECTIVE OF ELONGATION BY RNA POLYMERASE I. Suleyman Ucuncuoglu, David A. Schneider, David D. Dunlap, Laura Finzi

2565-P lat 1:30 pm THREE DIMENSIONAL RECONSTRUCTION OF THE NATIVE CARDIAC THIN FILAMENT DECORATED WITH MYOSIN- BINDING PROTEIN C FRAGMENT: IMPLICATIONS FOR CARDIAC REGULATION. Samantha Harris, Betty Virok, Howard White, Vitold E. Galkin 2566-P lat 1:45 pm NEW MODELS FOR REGULATION OF VINCULIN BY ACTIN AND PHOSPHOLIPIDS. Peter M. Thompson , Hyunna T. Lee, Laura Kim, Srinivas Ramachandran, Arpit Tandon, Raul Mendez-Giraldez, Gregory M. Alushin, Nikolay V. Dokholyan, Sharon L. Campbell 2567-P lat 2:00 pm TOWARDS A MODEL OF THE TAU-TUBULIN COMPLEX. Xiaohan Li , Jacob Culver, Elizabeth Rhoades 2568-P lat 2:15 pm MULTIPLE REVERSIBLE MOLECULAR EVENTS AT THE MICROTUBULE TIP DRIVE THE AGE-DEPENDENT MICROTUBULE CATASTROPHES. Pavel Zakharov, Nikita Gudimchuk, Vladimir Voevodin, Alexander Tikhonravov, Fazly I. Ataullakhanov, Ekaterina L. Grishchuk 2569-P lat 2:30 pm INTRINSICALLY DISORDERED MAP TAU MEDIATES BOTH SHORT-RANGE ATTRACTION AND LONG-RANGE REPULSION BETWEEN MICROTUBULES. Peter J. Chung , M.C. Choi, Uri Raviv, Herb P. Miller, Les Wilson, Stuart C. Feinstein, Cyrus R. Safinya 2570-P lat 2:45 pm EB1: A HIGHLY DYNAMIC AND DIFFUSIVE MICROTUBULE +TIP-TRACKING PROTEIN. Benjamin J. Lopez , Megan T. Valentine

1:00 pm –3:00 pm , R oom 316/317 Platform Actin Filaments and Microtubules

Co-Chairs Peter Chung, University of California, Santa Barbara Ekaterina Grishchuk, University of Pennsylvania 2563-P lat 1:00 pm

DIRECT MONOMER-BY-MONOMER OBSERVATION OF GELSOLIN-MEDIATED ACTIN FILAMENT NUCLEATION. Alvaro H. Crevenna , Maria Hoyer, Don C. Lamb 2564-P lat 1:15 pm ACTIN FILAMENT NUCLEATION IS INFLUENCED BY ELECTROSTATIC INTERACTIONS WITH THE BNI1P FORMIN FH2 DOMAIN. Joseph L. Baker , Naomi Courtemanche, Daniel L. Parton, Martin McCullagh, Thomas D. Pollard, Gregory A. Voth

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland