Biophysical Society 59th Annual Meeting Program Guide

N o A bstract 3:00 pm BAX CHANNELS: COOPERATIVITY AND VOLTAGE GATING. Marco Colombini 3:30 pm coffee break N o A bstract 4:00 pm STRUCTURE-GUIDED SIMULATIONS ILLUMINATE THE MECHANISM OF ATP TRANSPORT THROUGH VDAC1. Jeff Abramson 15-S ubg 4:30 pm VOLTAGE DEPENDENT ANION CHANNELS (VDAC) AND REGULATION OF MITOCHONDRIAL METABOLISM. John J. Lemasters 5:00 pm general discussion 5:15 pm subgroup business meeting 7:00 pm subgroup dinner

10:00 am –5:15 pm , R oom 316/317 Subgroup Mechanobiology

S A T U R D A Y

Subgroup Chair Dennis Discher, University of Pennsylvania 10:00 am

junior investigator talks selected from submitted abstracts “ lightning talks ” on mechanobiology

11:30 am 12:00 pm 19-S ubg

lunch break

1:05 pm ACTIN CORTEX MECHANICS AND CELL SHAPE CONTROL IN MIGRATION AND DIVISION. Ewa K. Paluch 20-S ubg 1:40 pm STIFFNESS SENSING THROUGH MYOSIN II MINIFILAMENTS. Ulrich S. Schwarz N o A bstract 2:15 pm CELL MIGRATION. Kenneth Yamada 2:50 pm break 21-S ubg 3:10 pm ADAPTATIVE RESPONSE OF CELL CYTOSKELETON RHEOLOGY AND ORDERING GOVERNS MATRIX RIGIDITY SENSING. Mukund Gupta, Bibhu Sarangi, Andrew Callan-Jones, Rene- Marc Mege, Raphael Voituriez, Benoit Ladoux 22-S ubg 3:45 pm MOLECULAR MECHANISMS OF CONTRACTILITY-BASED CELLULAR MECHANOSENSING. Douglas N. Robinson 23-S ubg 4:20 pm DYNEIN TEAMS ASSEMBLE ON LIPID RAFTS TO GENERATE LARGE FORCES ON PHAGOSOMES. Roop Mallik 24-S ubg 4:55 pm INVESTIGATION OF THE ENVZ/OMPR BACTERIAL SIGNALING SYSTEM USING SINGLE PARTICLE TRACKING AND SINGLE MOLECULE FORCE SPECTROSCOPY. Yong Hwee Foo , Ricksen Surya Winardhi, Jie Yan, Linda Kenney 5:15 pm business meeting

9:15 am –1:30 pm , R oom 321/322/323 Subgroup Molecular Biophysics

Subgroup Chair Zev Bryant, Stanford University

DYNAMICS OF MACROMOLECULAR MACHINES AND ASSEMBLIES

9:15 am 16-S ubg

opening remarks

9:30 am BENDING, TWISTING, POPPING: PROTEIN AND NUCLEIC- ACID REMODELING BY ATP-DEPENDENT MACHINES AND SWITCHES. James Berger N o A bstract 10:00 am SINGLE-MOLECULE ANALYSIS OF NUCLEOTIDE EXCISION REPAIR PATHWAYS. Terence Strick 17-S ubg 10:30 am DIRECT OBSERVATION OF STRUCTURE-FUNCTION RELATIONSHIPS IN NUCLEIC ACID PROCESSING ENZYMES. Yann Chemla 11:00 am coffee break 11:15 am subgroup business meeting N o A bstract 11:30 am VISUALIZING HOMOLOGOUS RECOMBINATION AT THE SINGLE-MOLECULE LEVEL USING DNA CURTAINS. Eric Greene N o A bstract 12:00 pm ENGINEERING MOLECULAR FUNCTIONS - SMALL- MOLECULE SENSORS AND CONTROLLABLE MACHINES. Tanja Kortemme N o A bstract 12:30 pm VISUALIZING THE STRUCTURAL PLASTICITY OF THE CYTOSKELETON. Gregory M. Alushin 18-S ubg 1:00 pm HIGH-RESOLUTION MAPPING OF INTRACELLULAR FLUCTUATIONS USING CARBON NANOTUBES. Nikta Fakhri 1:30 pm concluding remarks

10:00 am –6:30 pm , R oom 324/325 Subgroup Intrinsically Disordered Proteins

Subgroup Chair Elizabeth Komives, University of California, San Diego

INTRINSICALLY DISORDERED PROTEINS IN THEIR CELLULAR SETTINGS 10:00 am database discussion 10:20 am business meeting 12:30 pm welcome and announcements 12:40 pm introduction of opening keynote speaker N o A bstract 12:45 pm SINGLE-MOLECULE BIOPHYSICS OF INTRINSIC PROTEIN DISORDER. Ashok Deniz , Keynote Speaker

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland