Biophysical Society 59th Annual Meeting Program Guide

1000-S ymp 5:30 pm FUNCTIONAL ROLES OF GLUTAMATE TRANSPORT IN MODULATING PHASIC AND TONIC NEUROTRANSMITTER SIGNALING. Michael P. Kavanaugh 4:00 pm –6:00 pm , B allroom III Platform Cardiac Muscle Mechanics and Structure Co-Chairs Sabine van Dijk, University of Arizona Bertrand Tanner, Washington State University 1001-P lat 4:00 pm IMPLICATIONS OF ADP-STIMULATED CROSS-BRIDGE CYCLING FOR DIASTOLIC AND SYSTOLIC HEART FAILURE. Vasco Sequeira , Cris dos Remedios, Ger J.M. Stienen, Jolanda van der Velden 1002-P lat 4:15 pm MYOCARDIAL STRAIN RATE MODULATES THE SPEED OF RELAXATION IN DYNAMICALLY LOADED TWITCH CONTRACTIONS. Kenneth S. Campbell , Charles S. Chung 1003-P lat 4:30 pm MYOSIN MGADP RELEASE RATE DECREASES AT LONGER SARCOMERE LENGTH TO PROLONG MYOSIN ATTACHMENT IN SKINNED RAT MYOCARDIAL STRIPS. Bertrand CW Tanner , Peter O. Awinda, Jason J. Breithaupt 1004-P lat 4:45 pm INHERENT FORCE-DEPENDENT PROPERTIES OF β CARDIAC MYOSIN CONTRIBUTE TO THE FORCE-VELOCITY RELATIONSHIP OF CARDIAC MUSCLE. Michael J. Greenberg, Henry Shuman, E Michael Ostap 1005-P lat 5:00 pm EFFECT OF MUTATIONS IN CMYBP-C ON SARCOMERE MECHANICAL FUNCTION. Djordje Nedic , Marina Svicevic, Boban Stojanovic, Michael A. Geeves, Thomas Irving, Richard J. Gilbert, Srboljub M. Mijailovich 1006-P lat 5:15 pm THE A31P HCM MUTATION IN CMYBP-C DISRUPTS THE STRUCTURE OF THE C0 DOMAIN BUT DOES NOT CAUSE HAPLOINSUFFICIENCY IN A POPULATION OF OLDER CATS HETEROZYGOUS FOR THE A31P ALLELE. Sabine J. van Dijk , Kristina L. Bezold, Stacy Mazzalupo, Mark D. Kittleson, Alla S. Kostyukova, Samantha P. Harris 1007-P lat 5:30 pm CELL AND MYOFIBRIL CONTRACTILE PROPERTIES OF HIPSC-DERIVED CARDIOMYOCYTES FROM A PATIENT WITH A MYH7 MUTATION ASSOCIATED WITH FAMILIAL CARDIOMYOPATHY. Josè Manuel Pioner , Kai- Chun Yang, Lil Pabon, Alice Ward Racca, Mark Y. Jeong, Christian I. Childers, Jesse Macadangdang, Chiara Tesi, Corrado Poggesi, Deok- Ho Kim, Charles E. Murry, Michael Regnier 1008-P lat 5:45 pm MODULATION OF CARDIAC TWITCH DYNAMICS BY THE TROPONIN I INHIBITORY REGION. Yasser Aboelkassem, Jordan Bonilla, Stuart G. Campbell

4:00 pm –5:00 pm , R oom 301/302/303 Career Center Workshop Successfully Navigating the International Job Search Applying for a job in one country while finishing up your education and training in another can be challenging, but it can be done with success. In this workshop we will discuss specific strategies to finding jobs in another country while one is abroad and how to leverage your networks in-country to access opportunities, especially those that are hidden. Special emphasis will be placed on establishing your reputation as a leader in your field with professionals in the country or region in which you wish to work. Case studies will be shared. 4:00 pm –6:00 pm , B allroom I Symposium Bacterial Subcellular Dynamics at Super-Resolution: This Brings Super-Resolution to a Dynamic Sense Chair Julie Biteen, University of Michigan 993-S ymp 4:00 pm BEYOND MODEL SYSTEMS: SUPER-RESOLVING THE SUBCELLULAR DYNAMICS OF STARCH DIGESTION IN THE HUMAN GUT MICROBIOME. Krishanthi S. Karunatilaka, Elizabeth A. Cameron, Eric C. Martens, Nicole M. Koropatkin, Julie S. Biteen 994-S ymp 4:30 pm BACTERIAL CHROMOSOME SEGREGATION AT THE SINGLE- MOLECULE LEVEL. David Sherratt 995-S ymp 5:00 pm BACTERIAL CELL WALL PEPTIDOGLYCAN ARCHITECTURE AND DYNAMICS. Simon J. Foster 996-S ymp 5:30 pm 3D FOLDING MECHANISMS OF HIGHER-ORDER CHROMATIN TOPOLOGICAL DOMAINS. Marcelo Nollmann

M O N D A Y

4:00 pm –6:00 pm , B allroom II Symposium Neurotransmitter Transporters

Chair Olga Boudker, Weill Cornell Medical College 997-S ymp 4:00 pm

THE STRUCTURAL AND DYNAMIC BASIS OF ION-COUPLED SUBSTRATE UPTAKE BY A GLUTAMATE TRANSPORTER HOMOLOGUE. Olga Boudker 998-S ymp 4:30 pm FUNCTIONAL DYNAMICS OF GLUTAMATE/AMINO ACID TRANSPORTERS OF THE SOLUTE CARRIER 1 FAMILY. Christof Grewer 999-S ymp 5:00 pm TRANSPORTERS IN MOTION: COMBINING COMPUTATIONAL APPROACHES AND LRET-MEASUREMENTS. Harald H. Sitte , SanthoshKannan Venkatesan, Azmat Sohail, Kusumika Saha, Kumaresan Jayaraman, Gerhard F. Ecker, Michael Freissmuth, Walter Sandtner, Thomas Stockner

71

Biophysical Society 59 th Annual Meeting, Baltimore, Maryland