Biophysical Society 59th Annual Meeting Program Guide

1062-P os B oard B13 EFFECTS OF R102Q MUTATION ON THE STRUCTURAL AND DYNAMIC PROPERTIES OF HUMAN NEURONAL CALCIUM SENSOR-1 PROTEIN. Qingwen Zhang , Yuzhen Zhu, Ying Wu,

Protein Structure and Conformation II (Boards B1-B28) 1050-P os B oard B1 STRUCTURAL RIGIDITY REGULATES FUNCTIONAL INTERACTIONS IN THE HSP40-HSP70 MOLECULAR MACHINE. Neil Andrew D. Bascos , Samuel J. Landry 1051-P os B oard B2 STRUCTURAL STUDIES OF SOLUBLE GUANYLATE CYCLASE. Kenneth Childers , Franziska Seeger, Elsa Garcin 1052-P os B oard B3 GESTATION OF A GLU PLASMINOGEN SUPRA FOLD VIA MOLECULAR DYNAMICS SIMULATION. Hyunjin Kim , Hyung J. Kim, Miguel Llinas 1053-P os B oard B4 CONSTRAINED MAXIMUM LIKELIHOOD ESTIMATION OF THE ABUNDANCES OF PROTEIN CONFORMATION IN A HETEROGENEOUS STRUCTURAL ENSEMBLE FROM SMALL ANGLE X-RAY SCATTERING INTENSITY MEASUREMENTS. Ahmet Emre Onuk , Murat Akcakaya, Jaydeep Bardhan, Deniz Erdogmus, Dana H. Brooks, Lee Makowski 1054-P os B oard B5 USING PHYSICS AND HEURISTICS IN PROTEIN STRUCTURE PREDICTION. Alberto Perez , Justin MacCallum, Ken A. Dill 1055-P os B oard B6 ELUCIDATING THE FUNCTIONAL SIGNIFICANCE OF THE C-TERMINAL HYPERVARIABLE REGION (HVR) IN K-RAS4A. Mayukh Chakrabarti , Shaoyong Lu, Hyunbum Jang, Lyuba Khavrutskii, Nadya I. Tarasova, Vadim Gaponenko, Ruth Nussinov 1056-P os B oard B7 THEORETICAL STUDY OF THE PROTEIN FOLDING DYNAMICS FROM A TIME CORRELATION FUNCTION APPROACH. Toshifumi Mori , Shinji Saito 1057-P os B oard B8 EXTENSIVE CONFORMATIONAL HETEROGENEITY WITHIN PROTEIN CORES. Gregory R. Bowman 1058-P os B oard B9 CONFORMATIONAL DYNAMICS OF THE PILI CONSTRUCTING SORTASE C ENZYMES. Emmanuel B. Naziga , Jeff Wereszczynski 1059-P os B oard B10 TARGETED CONFORMATIONAL TRANSITIONS OF MULTIMERIC PROTEINS BY MONTE CARLO SIMULATIONS COMBINED WITH COLLECTIVE ANISOTROPIC NETWORK MODEL MODES. Yasemin Yesiltepe, Arzu Uyar, Deniz Turgut, Turkan Haliloglu, Pemra Doruker, Rahmi Ozisik 1060-P os B oard B11 CONFORMATIONAL FLUCTUATIONS AS AN INTRINSIC MECHANISM OF ACTION OF LIPASE FOLDASE STUDIED BY THE HIGH-PRECISION FRET TOOLKIT AND MD SIMULATIONS. Jakub Kubiak , Filip Kovacic, Peter Dollinger, Florian Bleffert, Karl-Erich Jaeger, Holger Gohlke, Claus A. M. Seidel 1061-P os B oard B12 NICKEL REDUCES CALCIUM-DEPENDANT DIMERIZATION BY NEURAL CADHERIN. Matthew P. Dukes , Rhianon Kay Rowe, Susan Pedigo

Buyong Ma 1063-P os

B oard B14

education travel awardee

RNA TRANSLOCATION COUPLED TO LARGE-SCALE CONFORMATIONAL TRANSITIONS OF A HEXAMERIC HELICASE. Wen Ma , Klaus Schulten 1064-P os B oard B15 IDENTIFYING UNIQUE CONFORMATIONS IN THERMUS THERMOPHILUS PHOSPHOFRUCTOKINASE USING FLUORESCENCE PHASORS. Xinxin Tian , Mauricio Lasagna, Gregory B oard B16 PROBING PROTEIN INTERACTIONS OF CYANYLATED ACYL CARRIER PROTEINS USING VIBRATIONAL SPECTROSCOPY. Connie Friedman , Michael Jordan, Casey Londergan, Louise Charkoudian 1066-P os B oard B17 IDENTIFICATION AND CHARACTERIZATION OF A YEAST ISO-1-CYTOCHROME C C-TERMINAL DOMAIN SWAPPED DIMER. Levi J. McClelland , Tung-Chung Mou, Stephen R. Sprang, Bruce E. Bowler 1067-P os B oard B18 HEME COORDINATION VERSATILITY IN A TRUNCATED HEMOGLOBIN. Dillon Nye , Matthew Preimesberger, Christos Kougentakis, Selena Rice, Juliette Lecomte 1068-P os B oard B19 MODELING THE CALCIUM AND INTEGRIN BINDING PROTEIN 2. Olivia Dickens , Raul Mendez-Giraldez, Nikolay B oard B20 STRUCTURAL BEHAVIOR OF CARDIAC TROPONIN C VARIANTS PRESENT IN CARDIOMYOPATHIC PATIENTS. Mayra Marques , José Pinto, Adolfo Moraes, Martha Sorenson, Jerson Silva, Guilherme Oliveira 1070-P os B oard B21 METHIONINE-AROMATIC INTERACTIONS IN CALMODULIN: A REPLICA EXCHANGE MD AND EPR SPECTROSCOPY STUDY. Tiffany L. Senkow , Andrew K. Lewis, Megan R. McCarthy, Cheng Her, David D. Thomas, Jonathan N. Sachs 1071-P os B oard B22 TARGETING MELANOMA WITH SMALL MOLECULES: INHIBITORS OF THE CALCIUM-BINDING PROTEIN S100B. Michael C. Cavalier , David J. Weber 1072-P os B oard B23 CRYSTALLIZATION STUDIES OF CALMODULIN BINDING TARGETS. Abigail L. Healy , Jennifer Willemsen, Katrina Nayak, Janina Sprenger, Roger Rowlett, Birgitta Frohm, Sara Linse, Karin Åkerfeldt 1073-P os B oard B24 TUNING OF STRUCTURE-FUNCTION RELATIONSHIPS BY MACROMOLECULAR CROWDING. Laurel Hoffman , Xu Wang, Hugo Sanabria, Margaret S. Cheung, John Putkey, Neal Waxham Dokholyan 1069-P os D. Reinhart 1065-P os

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland