Biophysical Society 59th Annual Meeting Program Guide

1293-P os B oard B244 education travel awardee UNRAVELING THE DUAL ROLE OF SURFACTANT PROTEIN A AT ATOMISTIC DETAIL. Boon Chong Goh , Michael J. Rynkiewicz, Francis X. McCormack, Barbara A. Seaton, Klaus Schulten 1294-P os B oard B245 IDENTIFYING THE CHOLINE-CATION TYROSINE-PI INTERACTIONS OF AN AMPHITROPIC PROTEIN. Tao He , Hanif M. Khan, Cedric Grauffel, Nathalie Reuter, Anne Gershenson, Mary F. Roberts 1295-P os B oard B246 MEMBRANE INTERACTION OF AMYLOID-BETA PEPTIDE INDUCES SPONTANEOUS MEMBRANE INVAGINATION. Sha Jin, Jörg Nikolaus, Andreas Herrmann, Jan Bieschke 1296-P os B oard B247 THE NOVEL INHIBITOR “ANLE145C” EFFICIENTLY INHIBITS FIBRIL FORMATION OF ISLET AMYLOID POLYPEPTIDE (IAPP) AND USES DISTINCTLY DIFFERENT MODES OF ACTION IN THE ABSENCE AND PRESENCE OF MEMBRANES. Manikam Sadasivam Saravanan , Sergey Ryazanov, Andrei Leonov, Janine Seeliger, Roland Winter, Armin Giese, Christian Griesinger, J Antoinette Killian 1297-P os B oard B248 INFLUENCE OF SEQUENCE AND LIPID TYPE ON MEMBRANE PERTURBATION BY HUMAN AND RAT AMYLOID β -PEPTIDE (1-42). Anne M. Brown , David R. Bevan ON FIBROBLAST GROWTH FACTOR RECEPTOR 3 DIMERIZATION. Nuala Del Piccolo , Kalina Hristova 1299-P os B oard B250 DECODING THE ROLE OF RECEPTOR DIMERIZATION IN PLEXIN-SEMAPHORIN SIGNALING. AdamW. Smith , Morgan Marita, Xiaojun Shi, William D. Comar 1300-P os B oard B251 SYNTHETIC MANIPULATION OF PIP2 LEVELS AND PIP2- ASSOCIATED CHEMOTACTIC SIGNALING DISSECTION IN DICTYOSTELIUM. Yuchuan Miao , Takanari Inoue, Peter Devreotes 1301-P os B oard B252 CHARGE SHIELDING OF PIP2 BY CATIONS REGULATES ENZYME ACTIVITY OF PHOSPHOLIPASE C. Jong Bae Seo , Seung- Ryoung Jung, Weigang Huang, Qisheng Zhang, Duk-Su Koh 1302-P os B oard B253 SOLUBLE AND IMMOBILIZED VEGF INDUCE DISTINCT PATTERNS OF VEGFR2 PHOSPHORYLATION MEDIATED BY INTRACELLULAR TRAFFICKING. Lindsay E W Clegg , Feilim Mac Gabhann 1303-P os B oard B254 MEASURING THE ENERGETICS OF EPHA3 DIMERIZATION IN LIVE MAMMALIAN CELLS. Qingqing Cao , Deo Singh, Chris King, Matt salotto, Kalina Hristova 1304-P os B oard B255 LOCAL BILAYER REORGANISATION BY THE JM REGIONS OF ALL HUMAN RTKS: A MULTISCALE MOLECULAR DYNAMICS STUDY. George Hedger , Mark S.P. Sansom, Heidi Koldsø Membrane Receptors and Signal Transduction II (Boards B249-B269) 1298-P os B oard B249 EFFECT OF THANATOPHORIC DYSPLASIA TYPE I MUTATIONS

1305-P os B oard B256 THE DIPOLE POTENTIAL INFLUENCES THE CLUSTERING OF ERBB PROTEINS. Tamas Kovacs , Agnes Szabo, Janos Szollosi, Peter Nagy 1306-P os B oard B257 HOMO AND HETERO DIMERIZATION OF RECEPTOR PROTEIN TYROSINE PHOSPHATASES. Elizabeth Dembicer , Maxwell Watkins, Damien Thevenin 1307-P os B oard B258 IN VIVO THERMODYNAMICS OF RTKS IN THE CELL MEMBRANE: QUANTITATIVE SPECTRAL FRET. Christopher R. King , Kalina Hristova 1308-P os B oard B259 COMPARISON OF EGFR DIMER STABILITIES IN THE PRESENCE AND ABSENCE OF THE LIGAND EGF. Matt Salotto , Deo R. Singh, Chris King, Pat Byrne, Daniel Leahy, Kalina Hristova 1309-P os B oard B260 LABEL-FREE CHARACTERIZATION OF A NOVEL EARLY-STAGE DRUG DISCOVERY PLATFORM. Edward Esposito , Verna Frasca, Kevin Mattison 1310-P os B oard B261 PATTERNED LIGAND SURFACES REVEAL F-ACTIN AND INTEGRIN ORGANIZATION AT EGF AND IGE RECEPTOR SIGNALING COMPLEXES. Devin Wakefield 1311-P os B oard B262 THE ENERGETICS OF THE CHROMOPHORE REGENERATION PATHWAY IN RHODOPSIN. He Tian , Thomas Sakmar, Thomas Huber 1312-P os B oard B263 international travel awardee LIGHT-INDUCED SWITCHING OF HAMP DOMAIN CONFORMATION AND DYNAMICS REVEALED BY TIME- RESOLVED EPR SPECTROSCOPY. Daniel Klose , Natalia Voskoboynikova, Philipp S. Orekhov, Ioan Orban-Glass, Christian Rickert, Martin Engelhard, Johann P. Klare, Heinz-Juergen Steinhoff 1313-P os B oard B264 DYNAMIC LIGAND-PROTEIN INTERACTIONS ALTER RHODOPSIN’S CONFORMATIONAL ENSEMBLE: SIMULATIONS OF RHODOPSIN AND OPSIN. Letty Salas , Nick Leioatts, Shairy Danial, Tod Romo, Alan Grossfield 1314-P os B oard B265 ATRAP (AT1R ASSOCIATED PROTEIN) ROLE ON ANGIOTENSIN II-MEDIATED NHE3 ACTIVITY MODULATION. Juliano Z. Polidoro , Nancy A. Rebouças 1315-P os B oard B266 ENVIRONMENTAL FACTORS ALLOWING STEM CELLS FROM SKELETAL MUSCLE TURNING INTO CARDIAC MUSCLE LIKE SPONTANEOUS BEATING CELLS. Hikari Hayashida, Wataru Yamasaki, Takayuki Miyanishi 1316-P os B oard B267 ROLES OF PHOSPHODIESTERASES IN CYCLIC NUCLEOTIDE CROSS-TALK IN CARDIAC MYOCYTES. Claire Y. Zhao , Joseph L. Greenstein, Raimond L. Winslow 1317-P os B oard B268 REGULATION OF THE CARDIAC β -ADRENERGIC PATHWAY VIA CAMP-CGMP COMPETITION. Claire Y. Zhao , Joseph L. Greenstein, Raimond L. Winslow

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland